GB832292A - 1ª‰-carboxy-5ª‰-hydroxy-8-ketohexahydronaphthalene lactone - Google Patents

1ª‰-carboxy-5ª‰-hydroxy-8-ketohexahydronaphthalene lactone

Info

Publication number
GB832292A
GB832292A GB3842457A GB3842457A GB832292A GB 832292 A GB832292 A GB 832292A GB 3842457 A GB3842457 A GB 3842457A GB 3842457 A GB3842457 A GB 3842457A GB 832292 A GB832292 A GB 832292A
Authority
GB
United Kingdom
Prior art keywords
hydroxy
carboxy
lactone
ketohexahydronaphthalene
hexahydronaphthalene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3842457A
Inventor
Georges Muller
Gerard Nomine
Julien Warnant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Francais de Chimiotherapie SA
Original Assignee
Laboratoires Francais de Chimiotherapie SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Francais de Chimiotherapie SA filed Critical Laboratoires Francais de Chimiotherapie SA
Priority to GB3842457A priority Critical patent/GB832292A/en
Publication of GB832292A publication Critical patent/GB832292A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises the racemic lactone of 1b - carboxy - 5b - hydroxy - 8 - oxo - 1 : 4 : 4aa : 5 : 8 : 8aa - hexahydronaphthalene, and the preparation thereof by lactonizing p the corresponding acid by heating with acetic anhydride and an alkali metal acetate in an inert solvent for the starting material. The product yields a hydroxy-lactone of the formula <FORM:0832292/IV (b)/1> on reduction by the Meerwein-Ponndorf process. Racemic 1b - carboxy - 5b - hydroxy - 8 - oxo - 1 : 4 : 4 : 4aa : 5 : 8 : 8aa - hexahydronaphthalene is prepared by condensing vinylacrylic acid with p-benzoquinone and reducing the resulting adduct with sodium borohydride.
GB3842457A 1957-12-10 1957-12-10 1ª‰-carboxy-5ª‰-hydroxy-8-ketohexahydronaphthalene lactone Expired GB832292A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3842457A GB832292A (en) 1957-12-10 1957-12-10 1ª‰-carboxy-5ª‰-hydroxy-8-ketohexahydronaphthalene lactone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3842457A GB832292A (en) 1957-12-10 1957-12-10 1ª‰-carboxy-5ª‰-hydroxy-8-ketohexahydronaphthalene lactone

Publications (1)

Publication Number Publication Date
GB832292A true GB832292A (en) 1960-04-06

Family

ID=10403343

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3842457A Expired GB832292A (en) 1957-12-10 1957-12-10 1ª‰-carboxy-5ª‰-hydroxy-8-ketohexahydronaphthalene lactone

Country Status (1)

Country Link
GB (1) GB832292A (en)

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