GB820169A - Improvements in nicotinic acid derivatives - Google Patents
Improvements in nicotinic acid derivativesInfo
- Publication number
- GB820169A GB820169A GB5387/56A GB538756A GB820169A GB 820169 A GB820169 A GB 820169A GB 5387/56 A GB5387/56 A GB 5387/56A GB 538756 A GB538756 A GB 538756A GB 820169 A GB820169 A GB 820169A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetrahydropyranylmethyl
- nicotinic acid
- reacting
- alcohol
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical class OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title abstract 9
- 235000001968 nicotinic acid Nutrition 0.000 abstract 5
- 239000011664 nicotinic acid Substances 0.000 abstract 4
- 229960003512 nicotinic acid Drugs 0.000 abstract 4
- -1 4-tetrahydropyranylmethyl esters Chemical class 0.000 abstract 3
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N methanol Natural products OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 2
- YNBADRVTZLEFNH-UHFFFAOYSA-N methyl nicotinate Chemical compound COC(=O)C1=CC=CN=C1 YNBADRVTZLEFNH-UHFFFAOYSA-N 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- 206010020565 Hyperaemia Diseases 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229960001238 methylnicotinate Drugs 0.000 abstract 1
- OFIRRWSYNLRPBX-UHFFFAOYSA-N oxan-2-ylmethyl pyridine-3-carboxylate Chemical compound C(C1=CN=CC=C1)(=O)OCC1OCCCC1 OFIRRWSYNLRPBX-UHFFFAOYSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000006173 tetrahydropyranylmethyl group Chemical group 0.000 abstract 1
- 238000005809 transesterification reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US430737A US2759945A (en) | 1954-05-18 | 1954-05-18 | Nicotinic acid esters of pyranmethanol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB820169A true GB820169A (en) | 1959-09-16 |
Family
ID=23708813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5387/56A Expired GB820169A (en) | 1954-05-18 | 1956-02-21 | Improvements in nicotinic acid derivatives |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US2759945A (enExample) |
| BE (1) | BE545605A (enExample) |
| CH (1) | CH341154A (enExample) |
| FR (1) | FR1179956A (enExample) |
| GB (1) | GB820169A (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2878251A (en) * | 1959-03-17 | Nicotinic acid ester of y-oxyethyl | ||
| US3126316A (en) * | 1964-03-24 | Process of increasing cholepoiesis with | ||
| SE322214B (enExample) * | 1965-06-28 | 1970-04-06 | Bofors Ab | |
| US10731651B2 (en) | 2016-02-23 | 2020-08-04 | Baker Hughes, A Ge Company, Llc | Apertures spaced around impeller bottom shroud of centrifugal pump |
| CN112824387B (zh) * | 2019-11-21 | 2023-03-21 | 济南尚博生物科技有限公司 | 一种2-甲基烟酸酯及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2524838A (en) * | 1946-06-04 | 1950-10-10 | Hoffmann La Roche | Esters of pyridyl-3-carbinol |
| US2514156A (en) * | 1946-12-20 | 1950-07-04 | Shell Dev | Substituted pyrans |
| NL66133C (enExample) * | 1947-03-14 |
-
1954
- 1954-05-18 US US430737A patent/US2759945A/en not_active Expired - Lifetime
-
1956
- 1956-02-21 GB GB5387/56A patent/GB820169A/en not_active Expired
- 1956-02-22 CH CH341154D patent/CH341154A/de unknown
- 1956-02-24 FR FR1179956D patent/FR1179956A/fr not_active Expired
- 1956-02-27 BE BE545605D patent/BE545605A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR1179956A (fr) | 1959-05-29 |
| US2759945A (en) | 1956-08-21 |
| BE545605A (enExample) | 1956-08-27 |
| CH341154A (de) | 1959-09-30 |
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