GB811770A - Method for hydrolyzing dextran - Google Patents

Method for hydrolyzing dextran

Info

Publication number
GB811770A
GB811770A GB3932756A GB3932756A GB811770A GB 811770 A GB811770 A GB 811770A GB 3932756 A GB3932756 A GB 3932756A GB 3932756 A GB3932756 A GB 3932756A GB 811770 A GB811770 A GB 811770A
Authority
GB
United Kingdom
Prior art keywords
dextran
molecular weight
water
dioxane
high molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3932756A
Inventor
Leo Joseph Novak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commonwealth Engineering Company of Ohio
Original Assignee
Commonwealth Engineering Company of Ohio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commonwealth Engineering Company of Ohio filed Critical Commonwealth Engineering Company of Ohio
Priority to GB3932756A priority Critical patent/GB811770A/en
Publication of GB811770A publication Critical patent/GB811770A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Dextran of molecular weight suitable for intravenous injection is produced by heating an aqueous acidic solution of higher molecular weight dextran containing 2.5 to 33 1/3 per cent by volume of water present of a non-solvent for the dextran consisting of a water-miscible aliphatic alcohol or ketone, or dioxane, at the boiing point of the water non-solvent mixture. The reaction mixture may also contain a reducing agent, preferably ascorbic acid. The high molecular weight dextran used as starting material is synthezized from sucrose by dextran sucrase in the presence or absence of bacteria. Examples describe the degradation of high molecular weight dextran using sulphuric or hydrochloric acid in the presence of isopropanol, ethanol, methanol, dioxane and acetone.
GB3932756A 1956-12-27 1956-12-27 Method for hydrolyzing dextran Expired GB811770A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3932756A GB811770A (en) 1956-12-27 1956-12-27 Method for hydrolyzing dextran

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3932756A GB811770A (en) 1956-12-27 1956-12-27 Method for hydrolyzing dextran

Publications (1)

Publication Number Publication Date
GB811770A true GB811770A (en) 1959-04-08

Family

ID=10408959

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3932756A Expired GB811770A (en) 1956-12-27 1956-12-27 Method for hydrolyzing dextran

Country Status (1)

Country Link
GB (1) GB811770A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114452440A (en) * 2015-06-10 2022-05-10 爱尔康公司 Intraocular lens materials and compositions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114452440A (en) * 2015-06-10 2022-05-10 爱尔康公司 Intraocular lens materials and compositions

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