GB804880A - Isocamphane compounds and their preparation - Google Patents
Isocamphane compounds and their preparationInfo
- Publication number
- GB804880A GB804880A GB2168/58A GB216858A GB804880A GB 804880 A GB804880 A GB 804880A GB 2168/58 A GB2168/58 A GB 2168/58A GB 216858 A GB216858 A GB 216858A GB 804880 A GB804880 A GB 804880A
- Authority
- GB
- United Kingdom
- Prior art keywords
- isocamphane
- acid
- sulphonic
- formylamino
- sulphonic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
- C07C211/38—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing condensed ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises (1) an isocamphane compound having the general formula: <FORM:0804880/IV (b)/1> in which R0 is an acyl radical derived from a C1-8 carboxylic acid and R1 is a hydrogen atom or a C1-8 alkyl group; (2) a process for producing 3-(N-formylamino)-isocamphane by contacting camphene with hydrogen cyanide in the presence of sulphuric acid or a sulphonic acid; (3) a process for producing 3-aminoisocamphane by reacting 3 - (N - formylamino) - isocamphane with a base; (4) a process for producing compounds of the above formula in which R1 is a hydrogen atom by reacting 3-aminoisocamphane with an acylating agent. In process (2) the reaction may be effected under anhydrous conditions, e.g. in glacial acetic acid using a cyanide salt and in the temperature range 0-5 DEG C. Examples of suitable sulphonic acids are methane sulphonic acid, ethane sulphonic acid, benzene sulphonic acids, toluene sulphonic acids, and naphthalene sulphonic acids; process (3) may be effected by refluxing in aqueous methanol solution and using sodium or potassium hydroxide. In process (4) the acylating agent may be the acid chloride, the acid itself or its anhydride, and the acylation may be effected in the presence of sulphuric acid. Examples describe the preparation of 3-(N - formylamino) - isocamphane, 3 - amino-isocamphane, 3 - acetamido - isocamphane, 3-(N - ethyl - N - acetylamino) - isocamphane, 3-(N - butyrylamino) - isocamphane and 3 - (N-3,3 - dimethylbutyrylamino) - isocamphane. Also mentioned are N-propionyl, N-hexanoyl, N-octanoyl, and N-isopropionyl derivatives of isocamphane.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US804880XA | 1955-06-06 | 1955-06-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB804880A true GB804880A (en) | 1958-11-26 |
Family
ID=22157701
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2168/58A Expired GB804880A (en) | 1955-06-06 | 1956-05-29 | Isocamphane compounds and their preparation |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB804880A (en) |
| MY (1) | MY6100100A (en) |
-
1956
- 1956-05-29 GB GB2168/58A patent/GB804880A/en not_active Expired
-
1961
- 1961-12-31 MY MY1961100A patent/MY6100100A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MY6100100A (en) | 1961-12-31 |
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