GB795490A - Microtome - Google Patents

Microtome

Info

Publication number
GB795490A
GB795490A GB10460/56A GB1046056A GB795490A GB 795490 A GB795490 A GB 795490A GB 10460/56 A GB10460/56 A GB 10460/56A GB 1046056 A GB1046056 A GB 1046056A GB 795490 A GB795490 A GB 795490A
Authority
GB
United Kingdom
Prior art keywords
bar
screw
knife
specimen
yoke
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB10460/56A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IVAN SORVALL Inc
Original Assignee
IVAN SORVALL Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IVAN SORVALL Inc filed Critical IVAN SORVALL Inc
Publication of GB795490A publication Critical patent/GB795490A/en
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G01N2001/065Drive details
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T83/00Cutting
    • Y10T83/647With means to convey work relative to tool station
    • Y10T83/654With work-constraining means on work conveyor [i.e., "work-carrier"]
    • Y10T83/6545With means to guide work-carrier in nonrectilinear path

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

795,490. Microtomes. SORVALL, Inc., I. April 5, 1956 [April 8, 1955], No. 10460/56. Class 97(1) A microtome comprises a first frame pivotally mounted about a substantially horizontal axis on a base and pivotally carrying a second frame to which a support is pivoted which carries a specimen holder on the end thereof adjacent a knife mounted on the base means being provided to move the specimen holder past the knife and for advancing it towards the knife, the specimen by-passing the knife during a portion of the movement of the holder. Fig. 2 shows the apparatus in which the specimen 266 is mounted in a chuck 262 on the end of a bar 111 pivoted about horizontal and vertical axes at the other end and moved by a crank to move the specimen past the cutting knife 358 for example of glass, the bar being fed towards the blade after each cut. The knife 358 is held by a screw 364, Fig. 12, against abutments 361 on a circular sleeve 357 supported in a collar on a stage 291, the collar being closed to clamp the sleeve 357, Fig. 12, by a cam operated by an arm 337. The stage 291 slides on a platform 271 slidable on the base 35, the stage 291 being pressed by springs against a coarse adjusting screw 322 on a bar 318 pivoted at 317 to the platform 271 and carrying a fine adjustment screw 319 bearing on a bracket 321 fixed to the base 35. By these screws the position of the stage 291 may be adjusted when the members 291 or 271 may be clamped together by a cam operated by an arm 303 and the platform 271 may be clamped to the base. Cyclical movement of the bar 111 to take the specimen past the knife is effected by a link 243, Fig. 13, connected at one end to a crank stud 241 eccentrically mounted on a disc 235 rotated by a hand wheel 231, the other end of the link 243 being loosely articulated with a horizontal pin 246 carried by the bar 111 adjacent the specimen. The bar is guided by an aperture 228 in a plate 225 so that on rotating the wheel 231 the bar 111 is guided down the vertical side B of the aperture to give the cutting stroke, and is returned to its initial position by way of the sloping lower side C of the aperture, the vertical side E and the upper side G during which vertical return between the bar 111 is fed forward a predetermined amount in preparation for the next cutting stroke. The bar 111, is supported at its other end by a pin 101, Fig. 4, mounted for rotation about a vertical axis in a block 91 rotatable about a horizontal axis in bearings 95, 96 carried by arms 81, 82 of a yoke 80 itself rotatable in bearings 65, 76 about a horizontal axis displaced vertically from that of the bearings 95, 96. Thus rotation of the yoke 80 about bearings 65, 76 causes a small horizontal movement of the bar 111 which feeds the specimen 266 towards the knife after each cutting stroke. This rotation of the yoke is effected by a rotatable screw 120 engaging a rider block 144 carried on a pair of arms 138 pivoted to the leg 87 of the yoke 80 so that rotation of the screw pivots the yoke about the bearings 65 and 76. This rotation is effected during the vertical return movement of the bar 111 by a rod 175 connected to the bar 111 by an arm 171 and pivoted at its lower end to a yoke 179, Fig. 7, pivoted on a shaft 181 coaxial with the screw 120 and carrying a pivoted shaft 185 bearing a pawl 186 adapted to engage a ratchet wheel 187 fixed to the screw 120 whereby vertical movement of the rod 175 causes the pawl and ratchet to rotate the screw to feed the bar 111 forward. The extent of the feeding movement is determined by engagement of a second pawl 191, fast to the shaft 185 with a cam disc 192 which holds the pawl 186 clear of the wheel 187 for a portion of the upward stroke of rod 175 dependent on the angular position of the disc 192 which is adjustable by gear 205 driven by a manually operated shaft 209. At the end of the feed movement the yoke 80, and with it the bar 111, may be returned to the initial position under the action of a spring 151, Fig. 5, by operation of a manually operated crank which moves a rod 155 to disengage the rider block 144 from the screw threads.
GB10460/56A 1955-04-08 1956-04-05 Microtome Expired GB795490A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US500110A US2822726A (en) 1955-04-08 1955-04-08 Microtome

Publications (1)

Publication Number Publication Date
GB795490A true GB795490A (en) 1958-05-21

Family

ID=23988075

Family Applications (1)

Application Number Title Priority Date Filing Date
GB10460/56A Expired GB795490A (en) 1955-04-08 1956-04-05 Microtome

Country Status (2)

Country Link
US (1) US2822726A (en)
GB (1) GB795490A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10935470B2 (en) * 2018-11-01 2021-03-02 Korea Basic Science Institute Ultra microtome device

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1150217B (en) * 1961-05-12 1963-06-12 Akad Wissenschaften Ddr Device for generating feed movements in ultramicrotomes
GB921405A (en) * 1961-07-03 1963-03-20 David Danon Improvements in and relating to microtomes
US3212379A (en) * 1962-10-26 1965-10-19 Ames Lab Tek Inc Microtome having means to incrementally feed the cutting blade toward the specimen carrier
US3299758A (en) * 1964-11-12 1967-01-24 John R Mcculloch Microtome
AT291623B (en) * 1968-03-20 1971-07-26 Compur Werk Gmbh & Co Microtome with a specimen holder
DE2246852A1 (en) * 1971-11-12 1973-05-30 Reichert Optische Werke Ag DEVICE FOR ADJUSTING THE ALTITUDE OF A PREPARATION FOR MICROTOMES, IN PARTICULAR ULTRAMICROTOMES
US3771405A (en) * 1972-09-08 1973-11-13 Sorvall Inc Ivan Microtome
US3841190A (en) * 1972-11-10 1974-10-15 Reichert Optische Werke Ag Apparatus for an infinite change of the vertical movement of the specimen in microtomes and ultramicrotomes
DE3433460A1 (en) * 1984-08-22 1986-03-06 Parke, Davis & Co., Morris Plains, N.J. LEADERSHIP
AT398848B (en) * 1990-01-19 1995-02-27 Sitte Hellmuth MICROTOM, IN PARTICULAR ULTRAMICROTOM
US7677289B2 (en) * 2004-07-08 2010-03-16 President And Fellows Of Harvard College Methods and apparatuses for the automated production, collection, handling, and imaging of large numbers of serial tissue sections
US20100093022A1 (en) * 2006-11-28 2010-04-15 Kenneth Hayworth Methods and apparatus for providing and processing sliced thin tissue
EP2614376B1 (en) 2010-09-07 2022-11-02 President and Fellows of Harvard College Methods and systems for collection of tissue sections
US9346429B2 (en) 2014-03-06 2016-05-24 Disney Enterprises, Inc. Passenger restraint pawl and ratchet assembly with positive engagement
CN113123786A (en) * 2021-06-02 2021-07-16 丑百雄 Grooving sampling device and geological surveying method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB189908258A (en) * 1899-04-19 1899-10-28 Horace Darwin Improvements in Microtomes.
US2155523A (en) * 1935-04-26 1939-04-25 Bausch & Lomb Microtome
US2439671A (en) * 1944-02-16 1948-04-13 Harvey N Ott Knife holder for microtomes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10935470B2 (en) * 2018-11-01 2021-03-02 Korea Basic Science Institute Ultra microtome device

Also Published As

Publication number Publication date
US2822726A (en) 1958-02-11

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