US2155523A - Microtome - Google Patents

Microtome Download PDF

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Publication number
US2155523A
US2155523A US18484A US1848435A US2155523A US 2155523 A US2155523 A US 2155523A US 18484 A US18484 A US 18484A US 1848435 A US1848435 A US 1848435A US 2155523 A US2155523 A US 2155523A
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United States
Prior art keywords
carriage
pawl
holder
microtome
arm
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Expired - Lifetime
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US18484A
Inventor
Bausch Edward
Fassin Gustave
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Bausch and Lomb Inc
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Bausch and Lomb Inc
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Publication date
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Priority to US18484A priority Critical patent/US2155523A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G01N2001/065Drive details
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T83/00Cutting
    • Y10T83/647With means to convey work relative to tool station
    • Y10T83/654With work-constraining means on work conveyor [i.e., "work-carrier"]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T83/00Cutting
    • Y10T83/647With means to convey work relative to tool station
    • Y10T83/6569With means to stop work conveyor
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T83/00Cutting
    • Y10T83/929Tool or tool with support
    • Y10T83/9457Joint or connection
    • Y10T83/9488Adjustable

Description

April 25, 1939.
E. BAuscH ET AL 2,155,523
MICROTOME Filed April 26, 1935 4 Sheets-Sheet l EDWARD BAUSCH GUSTAVE FASSI N INVENTOR ATTORNEY April 25, 1939.
E. BAUSCH ET AL MICROTOME Filed April 26, 1955 4 Sheets-Sheet 3 IOO FIG]
EDWARD BAUSCH GUSTAVE FASSI N INVENTOR ATTORNEY Patented Apr. 25, 1939 UNITED STATES PATENT OFFICE MICROTOIHE tion of New York Application April 26, 1935, Serial No. 18,484
12 Claims.
The present invention relates to microtomes for cutting sections of materials for microscopic examination.
One of the objects of the present invention is to provide a variable feed microtome which is durable and rugged in construction yet efficient and accurate in operation. Another object is to provide a compact microtome having a built-in power drive. A further object is to provide a microtome having a reciprocatory carriage and having a linear feed mechanism which does not apply torque to the carriage. Still another object is to provide a new and improved pawl and ratchet feed mechanism for a microtome in which mechanism the pawl is withdrawn from the ratchet during its non-feeding stroke. A further object is to provide a new and improved limiting means for the feed mechanism of a microtome. A further object is to provide a new and improved object holder for a microtome. A still further object is to provide a new and improved knife supporting clamp for a microtome. These and other objects and advantages reside in certain novel features of construction, arrangement and combination of parts as will hereinafter be more fully set forth and pointed out in the appended claims.
In the drawings:
Fig. 1 is a perspective view showing one side of a microtome made in accordance with this invention.
Fig. 2 is a perspective view showing the other side thereof.
Fig. 3 is a top plan view of the interior mechanism with parts in section.
Fig. 4 is a rear view of the interior mechanism.
Fig. 5 is a side elevation of the interior mechanism with parts in section.
Fig. 6 is a detail view of the pawl and ratchet mechanism in side elevation.
Fig. 7 is a fragmentary view of same in front elevation.
Fig. 8 is a detail view showing the object holder and clamp in vertical section.
A preferred embodiment of this invention is illustrated in the drawings wherein ||l indicates the base of a microtome having a feed mechanism housing indicated generally at and a knife holder indicated generally at |2. The feed mechanism housing II has a front wall l3, two side walls l4 and 15 and a cover |6 hinged near the base H] for closing the top and rear.
A shaft |1 mounted in bearings l8 and I9 extends through the side wall I4 and has a fly wheel and an operating handle 2| secured thereto outside of the housing Within the housing,
the shaft I1 is connected by suitable gears 22 and 23 to a shaft 24 which is in turn connected to the motor 25 through a suitable one-way drive indicated generally at 26. An eccentric 21 is secured to the inner end of the shaft H for a purpose to be described later.
The front wall I3 is formed with a vertical slot 28 and a plate 29 is mounted in bearings on each side of the slot 28 for vertical reciprocatory motion. A carriage 30 is secured to the plate 29 extending rearwardly therefrom in a horizontal direction and has on one side a horizontal recess 3| in which a block 32 is slidable. This block is pivotally connected to the eccentric 21' so that rotation of the shaft |1 will reciprocate the carriage 30 and the plate 29. Two members 33 and 34 are secured to the top of the carriage 30 to form a second horizontal guideway 35. An object holder 36 is slidably mounted in the guideway 35 with its axial center passing through the center of the plate 26.
A screw 31 is journalled in bearings 38 and 39 within the carriage 30 with its axis parallel to the axis of the object holder 36. The object holder 36 is provided with an aperture 40 through which the nut 4| extends to engage the screw 31. The top portion 42 of the nut 4| extends beyond the aperture 40 and is securely fastened to the object holder 36 by bolts 43 and 44. The rear end of the screw 31 is provided with a gear 45 for engaging a worm 46 which is fixed to a shaft 41 journalled in bearings 48 and. 49 on the carriage 30. A ratchet 50 is fixed near the outer end of the shaft 41 for receiving power intermittently to drive the screw 31.
Freely rotatable on the shaft 41 is an arm 5| carrying a pawl 52 for engaging the ratchet 5|]. The pawl 52 is pivoted at 53 on the arm 5| and a spring 54 urges the pawl into engagement with the teeth of the ratchet 50. A second arm 55 immediately adjacent the arm 5| is also freely rotatable on the shaft 41. A pin 56 is secured to the arm 55 and extends between an edge of the arm 5| and a stop 51 on the pawl 52 thus forming a lost motion driving connection between the arms 5| and 55. The pawl 52 has a cam portion 58 in the path of the pin 56 so that when the pin 56 is moved toward the stop 51, the pawl 52 is pivoted out of engagement with the ratchet teeth before any rotary movement of the arm 55 is transmitted to the arm 5|. One end of a link 59 is pivoted at 60 to the wall l4 while the other end is pivoted at 6| eccentrically of the arm 55. Thus when the carriage 30 is reciprocated by the eccentric 21, the link 59 will cause the arm 5| and pawl 52 to oscillate and turn the ratchet 56.
Adjacent the ratchet 56 on the side opposite the arms 5| and 55, a sector shaped pawl lifter 62 is freely rotatable on the shaft 41. The peripheral edge of the pawl lifter 62 cooperates with a rotatable extension 63 on the pawl 52 to hold the pawl out of engagement with the ratchet 56 and by changing the angular position of the pawl lifter 62, the amount of feeding movement imparted by the pawl is changed without the necessity of changing the length of the stroke. Fixed to the pawl lifter 62 is a gear 64 which engages a gear 65 on a shaft 66 journalled in a bearing 61 on the carriage 36. The shaft 66 is universally connected at 68 to an extensible link 69 which in turn is universally connected at 16 to a shaft II leading to the feed setting dial 12.
A gear 13 is fixed on the shaft 41 and meshes with a pinion 14 on a shaft 15 journalled in a bearing 16 on the carriage 36. The shaft 15 is universally connected at 11 to an extensible link 18 which is universally connected at 19 to a shaft 86 rotatably mounted in the wall I5 and carrying a crank 8|. By means of the crank 8| acting through the gear 13 and pinion 14 the screw 31 can be rotated to return the object holder 36 from its forward position.
The extent of forward movement of the object holder 36 is limited by a shielding cam 82 pivotally connected at 83 to the carriage 36. As shown in Fig. 6 the left hand side of the shielding cam 82 is movable to a position where it engages the rotatable extension 63 on the pawl 52 to hold the pawl 52 out of engagement with the teeth of the ratchet 56 throughout its entire stroke. The right hand side of the shielding cam 82 is formed with a projection 84. As shown in Fig. 5 the projection 84 rests against a stop 85 on the carriage 36 when the shielding cam 82 is in its inoperative position. A trigger 86 is pivotally mounted at 81 on a bracket 88 fixed to the object holder 36, and is normally held in a vertical position by a spring 89. As the object holder 36 is fed forward the trigger 86 engages the stop 85 and the spring 89 is placed under tension. When the trigger 86 passes over the stop 85, the spring 89 snaps the trigger 86 into engagement with the projection 84 and the shielding cam 82 is moved to its shielding position so that even though the motor 25 continues to run and reciprocate the carriage 36, there will be no feeding of the object holder 36.
The front end of the object holder 36 is an internally threaded hollow socket 96 in which is seated a hollow spherical cup 9|. A spherically surfaced nut 92 engages the inner surface of the cup 9| and is secured by a lock nut 93 to a shaft 94 extending through an aperture 95 in the cup 9|. The shaft 94 terminates in a head 96 having a radial slot 91 and a pin 98 fixed in the object holder 36 holds the head 96 and shaft 94 against rotation. A nut 99 threaded in the hollow socket 96 is rotatably carried on the shaft 94 in engagement with the head 96. The nut 99 is rotatable by a handle I66 which extends through a slot ml in the hollow socket on the object holder 36. A cover ring I62 serves to protect the interior of the socket against the entry of dust or dirt through the slot I6 I. The object or specimen to be cut is clamped in the cup 9| by a jaw I63 operated by a thumb screw I64.
The knife holder I 2, which is substantially the same as that described in U. S. Patent 1,765,283 issued June 17, 1930, to W. L. Patterson and G.
B. Gallasch, has two spaced upright members I65 and I66 rigidly connected by a web I61. The upright members I65 and I66 are arcuate on their bottom surfaces and rest on the arcuate block I68 which is slidably mounted on the base I6 of the microtome. The center of this arcuate curve is the cutting edge of the knife. The block I68 can be locked in position on the base I6 by a handle I69 and carries a clamping member II6 under the control of a handle I I I for locking the knife holder I2 in desired position. Each of the upright members I65 and I66 has an aperture or bore H2 and an adjusting screw 3 extends from the knife clamp into this aperture or bore and terminates in an enlarged head H4. The enlarged head 4 for adjusting the knife vertically is thus rendered easily accessible. The uprights I 65 and I66 are provided respectively with rigid shields H5 and 6.
In operation, the dial 12 controlling the pawl lifter 62 is set for the desired thickness and the motor 25 is started at the desired speed by means of the switch 1 and governor H8. The motor drive is transmitted through the one-Way drive 26, the shaft 24 and gears 23 and 22 to the eccentric 21 which reciprocates the carriage 36. This reciprocating movement causes the pawl 52 to rotate the ratchet 56 intermittently and, though shaft 41, worm 46, wheel 45 and screw 31, to feed the object holder 36 toward the knife holder I2. When the object holder 36 reaches the forward limit of its travel, the trigger 66 passes over the stop 85 and engages the projection 64 on the shielding cam 82 moving the cam 82 to a position where it holds the pawl 52 out of engagement with the ratchet 56. The carriage may be retracted by the crank 8| which serves to rotate the screw 31 through the wheel 45, worm 46, shaft 41 and gears 13 and 14.
From the foregoing it is apparent that we are able to attain the objects of our invention and provide a new and improved microtome which is durable and rugged in operation yet efficient and accurate in operation.
We claim:
1. In a microtome a base, a carriage reciprocably carried by said base, means for reciprocating said carriage, an object support slidably mounted on said carriage, a screw mounted on said carriage for moving said object support, a ratchet wheel mounted upon said carriage for rotating said screw, a pawl, an actuating link for said pawl pivotally carried by said base for actuating said ratchet wheel and means for disengaging said pawl from said ratchet upon predetermined movement of said object support in one direction.
2. In a microtome a carriage, an object support slidably mounted on said carriage, pawl and ratchet means for sliding said object support, shielding means movable to a position where said pawl is held out of engagement with said ratchet wheel, means mounted upon said object support to move said shielding means into its shielding position upon a predetermined travel of said object support and means on the support for holding the shielding means in shielding position.
3. In a microtome a base, a carriage reciprocably carried by said base, an object holder movably mounted upon said carriage, means including a pawl and a ratchet wheel for moving said object holder, shielding means carried by said carriage for shielding said ratchet wheel from said pawl, a trigger carried by said object holder for moving said shielding means into shielding position, and a release for said trigger mounted on said carriage whereby said shielding means is moved quickly to its shielding position upon predetermined relative movement between said carriage and said object holder.
4. In a microtome a base, a carriage reciprocably mounted upon said base, an object support slidably mounted upon said carriage, a screw carried by said carriage for moving said object support, a ratchet wheel carried by said carriage for rotating said screw, a pawl arm oscillatably mounted on said carriage concentrically with said ratchet wheel for actuating said ratchet wheel, a pawl carried by said pawl arm, a pawl lifter rotatably mounted on said carriage concentrically with said ratchet wheel and means for moving said pawl lifter whereby the extent of rotation of said ratchet wheel may be changed without changing the extent of the oscillation of said pawl arm.
5. In a microtome having a base, a wall carried by said base, a carriage reciprocably carried by said base, an object holder movably carried by said carriage, a screw rotatably mounted on said carriage for moving said object holder, a ratchet wheel carried by said carriage for actuating said screw, means independent of said ratchet wheel for actuating said screw, a handle rotatably carried by said wall and means interconnecting said handle and said actuating means.
6. In a microtome a casing, a carriage reciprocably carried by said casing, mechanism for reciprocating said carriage, an object holder slidably mounted on said carriage, means on said carriage for sliding said object holder longitudinally, a ratchet wheel rotatably mounted on said carriage for actuating said means, a pawl pivotally carried by said carriage for actuating said ratchet wheel, and a link pivotally connected to said casing and operatively connected tosaid pawl so that reciprocation of said carriage actuates said pawl.
'7. In a microtome a casing, a knife holder mounted on said casing, guides mounted on said casing, a carriage reciprocably mounted on said guides, an object support slidably mounted on said carriage, a screw carried by said carriage for sliding said object support toward said knife holder, a ratchet wheel carried by said carriage for rotating said screw, an arm pivotally mounted on said carriage coaxially with said ratchet wheel, a pawl mounted on said arm for engaging said ratchet wheel, a link operatively connected eccentrically of said arm and. pivotally connected to said casing, and means for reciprocating said carriage.
8. A microtome comprising an object holder adapted to be reciprocated, a knife holder having a cylindrically curved base upon which it is movably mounted, said curved base defining the arc of a cylinder whose axis lies above said knife holder, said knife holder having a large bore therethrough extending substantially parallel to said cylinder axis, clamping means on said knife holder for securing a knife blade therein, spaced means for leveling said knife blade and for moving same into coincidence with said cylinder axis, said means extending into said bore.
9. In a microtome a base, an adjustable knife holder mounted on said base, a knife'adiustably carried by said knife holder, guides mounted on said base, a carriage reciprocably mounted on said guides, an object support slidably mounted on said carriage, a screw carried by said carriage for sliding said object support toward said knife holder, means for adjusting said knife holder for varying the cutting angle of said knife relative to said object support, means for locking said knife holder in adjusted position, a ratchet wheel carried by said carriage for rotating said screw, an arm pivotally mounted on said carriage coaxially with said ratchet wheel, a pawl mounted on said arm for engaging said ratchet wheel, a link operatively connected eccentrically of said arm and pivotally connected to said base, and means for reciprocating said carriage.
10. A microtome comprising a base, a knife carried by said base, a carriage reciprocably carried by said base, an object support slidably mounted on said carriage for movement toward and from said knife, a screw operatively connected to said support for moving said support toward said knife and a feeding mechanism operatively connected to said screw for intermittently rotating said screw, said mechanism comprising a rotatably mounted ratchet wheel, an arm rotatably mounted substantially coaxially with said ratchet wheel, a pawl pivotally mounted upon said arm for feeding engagement with said ratchet wheel, actuating means for oscillating said arm and means interconnecting said actuating means and said arm for withdrawing said pawl from said ratchet wheel uponv movement in its non-feeding direction.
11. A microtome comprising a base, a knife carried by said base, a carriage reciprocably carried by said base, an object support slidably mounted on said carriage for movement toward and from said knife, a screw operatively connected to said support for moving said support toward said knife and a feeding mechanism operatively connected to said screw for intermittently rotating said screw, said mechanism comprising a rotatably mounted ratchet wheel, an arm pivotally mounted coaxially with said wheel, a pawl pivotally mounted on said arm for feeding engagement with said ratchet wheel, a sec-- and arm pivotally mounted coaxially with said ratchet wheel and said first arm, a lost motion connection between said arms, cam means between said second arm and said pawl for withdrawing said pawl from said ratchet wheel during said 10st motion upon movement in its nonfeeding direction and means for oscillating said second arm.
12. In a microtome, a knife, an object support, means for reciprocating said support, feeding means for moving said support towards said knife in a direction perpendicular to the direction of reciprocation, a motor for driving both said means, means: for disengaging said feeding means, and means on said support for actuating said disengageing means and holding said disengaging means in disengaging relation, upon a predetermined extent of movement of said support toward said knife.
EDWARD BAU'SCH.
GUSTAVE FASSIN.
US18484A 1935-04-26 1935-04-26 Microtome Expired - Lifetime US2155523A (en)

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Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2822726A (en) * 1955-04-08 1958-02-11 Sorvall Inc Ivan Microtome
US2875669A (en) * 1952-11-06 1959-03-03 Lkb Produkter Farbiksaktiebola Microtome
US2948190A (en) * 1958-01-09 1960-08-09 Sorvall Inc Ivan Microtome bypass slide
US3212379A (en) * 1962-10-26 1965-10-19 Ames Lab Tek Inc Microtome having means to incrementally feed the cutting blade toward the specimen carrier
US3405578A (en) * 1965-04-07 1968-10-15 Lkb Produkter Aktiebolag Method for measuring the true cutting edge angle of a knife for a microtome
US3491638A (en) * 1967-05-31 1970-01-27 Int Equipment Co Reversible drive for microtome feed screw
US3699830A (en) * 1971-03-22 1972-10-24 John E P Pickett Method utilizing a disposable blade in microtome cutting
US3926085A (en) * 1974-12-02 1975-12-16 American Optical Corp Specimen feed for a microtome
EP0175480A1 (en) * 1984-08-22 1986-03-26 PARKE, DAVIS & COMPANY Guide device for guiding a movable part of an apparatus relative to a fixed part of the apparatus
US4690023A (en) * 1984-04-07 1987-09-01 Cambridge Instruments Inc. Clamping mechanism for a cutter of a microtome
US6209437B1 (en) * 1994-08-15 2001-04-03 Micron Laborgerate Gmbh Microtome
DE10244687A1 (en) * 2002-09-24 2004-04-01 Hirt, Rüdiger rotary microtome
US20040120862A1 (en) * 2002-12-11 2004-06-24 Leica Mikrosysteme Gmbh Specimen holder having an insert for atomic force microscopy
GB2456033A (en) * 2007-12-27 2009-07-01 Leica Biosystems Nussloch Gmbh Microtome with concentric motor control means
USD668347S1 (en) * 2010-12-02 2012-10-02 Leica Biosystems Nussloch Gmbh Microtome
WO2013095972A3 (en) * 2011-12-21 2013-08-15 Sakura Finetek U.S.A., Inc. Reciprocating microtome drive system
US8869666B2 (en) 2011-03-24 2014-10-28 Sakura Finetek U.S.A., Inc. Microtome with surface orientation sensor to sense orientation of surface of sample

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2875669A (en) * 1952-11-06 1959-03-03 Lkb Produkter Farbiksaktiebola Microtome
US2822726A (en) * 1955-04-08 1958-02-11 Sorvall Inc Ivan Microtome
US2948190A (en) * 1958-01-09 1960-08-09 Sorvall Inc Ivan Microtome bypass slide
US3212379A (en) * 1962-10-26 1965-10-19 Ames Lab Tek Inc Microtome having means to incrementally feed the cutting blade toward the specimen carrier
US3405578A (en) * 1965-04-07 1968-10-15 Lkb Produkter Aktiebolag Method for measuring the true cutting edge angle of a knife for a microtome
US3491638A (en) * 1967-05-31 1970-01-27 Int Equipment Co Reversible drive for microtome feed screw
US3699830A (en) * 1971-03-22 1972-10-24 John E P Pickett Method utilizing a disposable blade in microtome cutting
US3926085A (en) * 1974-12-02 1975-12-16 American Optical Corp Specimen feed for a microtome
US4690023A (en) * 1984-04-07 1987-09-01 Cambridge Instruments Inc. Clamping mechanism for a cutter of a microtome
EP0175480A1 (en) * 1984-08-22 1986-03-26 PARKE, DAVIS & COMPANY Guide device for guiding a movable part of an apparatus relative to a fixed part of the apparatus
US6209437B1 (en) * 1994-08-15 2001-04-03 Micron Laborgerate Gmbh Microtome
DE10244687A1 (en) * 2002-09-24 2004-04-01 Hirt, Rüdiger rotary microtome
US7727481B2 (en) * 2002-12-11 2010-06-01 Leica Mikrosysteme Gmbh Specimen holder having an insert for atomic force microscopy
US20040120862A1 (en) * 2002-12-11 2004-06-24 Leica Mikrosysteme Gmbh Specimen holder having an insert for atomic force microscopy
US20090165627A1 (en) * 2007-12-27 2009-07-02 Roland Walter Microtome having concentric operating elements for controlling a motor unit
GB2456033B (en) * 2007-12-27 2010-02-10 Leica Biosystems Nussloch Gmbh Microtome with concentric motor control means
GB2456033A (en) * 2007-12-27 2009-07-01 Leica Biosystems Nussloch Gmbh Microtome with concentric motor control means
US8051760B2 (en) 2007-12-27 2011-11-08 Leica Biosystems Nussloch Gmbh Microtome having concentric operating elements for controlling a motor unit
USD668347S1 (en) * 2010-12-02 2012-10-02 Leica Biosystems Nussloch Gmbh Microtome
US8869666B2 (en) 2011-03-24 2014-10-28 Sakura Finetek U.S.A., Inc. Microtome with surface orientation sensor to sense orientation of surface of sample
US9347857B2 (en) 2011-03-24 2016-05-24 Sakura Finetek U.S.A., Inc. Microtome with surface orientation sensor to sense orientation of surface of sample
WO2013095972A3 (en) * 2011-12-21 2013-08-15 Sakura Finetek U.S.A., Inc. Reciprocating microtome drive system
US9032854B2 (en) 2011-12-21 2015-05-19 Sakura Finetek U.S.A., Inc. Reciprocating microtome drive system
US9921137B2 (en) 2011-12-21 2018-03-20 Sakura Finetek U.S.A., Inc. Reciprocating microtome drive system
EP3370055A1 (en) 2011-12-21 2018-09-05 Sakura Finetek U.S.A., Inc. Reciprocating microtome drive system

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