GB786944A - A novel carbinol and salts thereof and a process for the manufacture of same - Google Patents
A novel carbinol and salts thereof and a process for the manufacture of sameInfo
- Publication number
- GB786944A GB786944A GB9856/56A GB985656A GB786944A GB 786944 A GB786944 A GB 786944A GB 9856/56 A GB9856/56 A GB 9856/56A GB 985656 A GB985656 A GB 985656A GB 786944 A GB786944 A GB 786944A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- carbinol
- salts
- diphenyl
- piperidyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
The invention comprises diphenyl-[piperidyl-(3)]-carbinol, and acid addition salts thereof, and the preparation thereof by reacting a lower alkyl ester of nipecotic acid with phenyl magnesium halide and hydrolysing the product so formed, or by catalytically reducing diphenyl-[pyridyl-(3)]-carbinol in acidic alcoholic medium with hydrogen in the presence of a platinum dioxide catalyst, e.g. Adan's platinum dioxide catalyst, and when salts are required treating the diphenyl - [piperidyl - (3)] - carbinol with an acid. Suitable acids for the salt formation step are inorganic acids such as hydrochloric, hydrobromic, hydriodic, nitric, phosphoric, sulphuric, perchloric, silicotungstic, chloroplatinic and Reinecke's acid, and organic acids such as acetic, citric, malic, maleic, tartaric, glycolic, levulinic, ethane-sulphonic and d-camphor-sulphonic acid. In the examples, the dl-free base is prepared by both of the methods referred to above, and is converted into the hydrochloride, d-tartrate, l-tartrate, l-malate, oxalate and nitrate salts.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US786944XA | 1955-03-30 | 1955-03-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB786944A true GB786944A (en) | 1957-11-27 |
Family
ID=22145655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB9856/56A Expired GB786944A (en) | 1955-03-30 | 1956-03-29 | A novel carbinol and salts thereof and a process for the manufacture of same |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB786944A (en) |
-
1956
- 1956-03-29 GB GB9856/56A patent/GB786944A/en not_active Expired
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB804036A (en) | A process for the manufacture of a sulphanilamide of the isoxazole series | |
GB835526A (en) | A method for preparing polyene-carboxylic acids and their derivatives | |
GB786944A (en) | A novel carbinol and salts thereof and a process for the manufacture of same | |
GB904117A (en) | Improvements in or relating to catalytic reduction of pyridine and pyridine salts | |
GB680255A (en) | 7-chloro-4-[5-(n-ethyl-n-2-hydroxyethylamino)-2-pentyl]aminoquinoline and the preparation thereof | |
GB908203A (en) | Process for the production of n,n-dimethyl-d-glucosamine, its salts and acetyl derivatives thereof | |
ES269744A1 (en) | A process for the preparation of 4-acyloxy-and 4-hydroxy-3-keto-í -steroids | |
GB1070192A (en) | N-vinyl-carbamic acid esters and process for their manufacture | |
ES290184A1 (en) | Procedure for obtaining dibenzocicloheptenes (Machine-translation by Google Translate, not legally binding) | |
ES456928A1 (en) | Manufacture of butenediol diesters | |
GB805885A (en) | 3-substituted-8-alkylnortropanes and the acid and quaternary ammonium salts thereof | |
ES255092A1 (en) | Procedure for the preparation of cis-9 -heptadecenic acid and cis-9 -pentadecenic, as well as salts from these acids (Machine-translation by Google Translate, not legally binding) | |
GB763406A (en) | Novel 6-aminomethyl-5-hydroxy-indane derivatives and a process for the manufacture thereof | |
GB819129A (en) | Therapeutic compositions containing 1-(2,4-dimethyl-phenyl)-2-amino-propane and a process for the manufacture thereof | |
GB945505A (en) | New steroid compounds and processes for their preparation | |
GB848690A (en) | Improvements in or relating to compounds having spasmolytic effects | |
GB826487A (en) | 1-thienyl-3-amino-propanol derivatives | |
GB801712A (en) | Alpha-phenyl, alpha-(4-piperidyl)-benzyl alcohol and the preparation thereof | |
GB778947A (en) | Process for the dehydration of dimethylphenylcarbinol | |
ES441402A1 (en) | A procedure for the preparation of new derivatives of benzyl alcohol. (Machine-translation by Google Translate, not legally binding) | |
GB975602A (en) | Derivatives of 14-hydroxynorcodeinone and their production | |
GB830869A (en) | Process for the preparation of beta-piperidinoethyl-alpha-phenyl-alpha-piperidinoacetate and its dihydrochloride | |
GB793226A (en) | 6-dimethylamino-4:4-diphenyl-3-heptanone n-oxide and its salts | |
ES245676A1 (en) | Procedure for obtaining (Machine-translation by Google Translate, not legally binding) | |
DE98210A (en) |