GB771768A - Improved dental therapeutic compositions - Google Patents

Improved dental therapeutic compositions

Info

Publication number
GB771768A
GB771768A GB33627/54A GB3362754A GB771768A GB 771768 A GB771768 A GB 771768A GB 33627/54 A GB33627/54 A GB 33627/54A GB 3362754 A GB3362754 A GB 3362754A GB 771768 A GB771768 A GB 771768A
Authority
GB
United Kingdom
Prior art keywords
paste
vehicle
sodium
sorbitol
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB33627/54A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Pharmaceutical Co filed Critical Warner Lambert Pharmaceutical Co
Publication of GB771768A publication Critical patent/GB771768A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/04—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

A dental preparation comprises a compound of formula <FORM:0771768/VI/1> where R represents an alkyl, hydroxy-tertiary butyl, butylamino-propyl or dicyclohexyl group and a compatible vehicle. The preparation may be in the form of a paste, powder or liquid dentifrice, mouthwash, chewing gum, tablet or troche. R may be isopropyl, secondary butyl, ethylhexyl, dodecly, tetradecyl and hexadecyl groups. A concentrate of the pyrimidine compound and a surface active agent (an ethanolamine salt or a sorbitan ether-ester) may be prepared and added to the vehicle. Water-soluble oxolates, e.g. sodium, potassium, ammonium or the urea salt, may also be present in addition to the conventional vehicle. Example 1 describes a paste dentifrice comprising 1:3 - di - (ethyl hexyl) - 5 - methyl - 5 - amino - hexahydropyrimidine and a complex sorbitol ether-ester dispersing agent in a paste comprising calcium sulphate, calcium phosphate, sodium lauryl-sulphoacetate, gum tragacanth, sodium saccharin, glycerine, d - sorbitol, flavouring and water.
GB33627/54A 1953-11-19 1954-11-19 Improved dental therapeutic compositions Expired GB771768A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US771768XA 1953-11-19 1953-11-19

Publications (1)

Publication Number Publication Date
GB771768A true GB771768A (en) 1957-04-03

Family

ID=22136514

Family Applications (1)

Application Number Title Priority Date Filing Date
GB33627/54A Expired GB771768A (en) 1953-11-19 1954-11-19 Improved dental therapeutic compositions

Country Status (1)

Country Link
GB (1) GB771768A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522806A (en) * 1980-10-10 1985-06-11 Lever Brothers Company Oral compositions for hexetidine and zinc salts for the synergistic inhibition of dental plaque
GB2174902A (en) * 1985-05-10 1986-11-19 Dansk Tyggegummi Fabrik As A solid, oral anticariogenic chewing gum or lozenge
EP0340171A2 (en) * 1988-04-27 1989-11-02 Warner-Lambert Company Cyclodextrin complexes of 5-aminohexahydropyrimidine compounds
GB2245830A (en) * 1990-06-12 1992-01-15 Ghomi Mina Safai Medicament and cosmetics for treating skin and hair conditions

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522806A (en) * 1980-10-10 1985-06-11 Lever Brothers Company Oral compositions for hexetidine and zinc salts for the synergistic inhibition of dental plaque
GB2174902A (en) * 1985-05-10 1986-11-19 Dansk Tyggegummi Fabrik As A solid, oral anticariogenic chewing gum or lozenge
GB2174902B (en) * 1985-05-10 1990-03-14 Dansk Tyggegummi Fabrik As A solid oral anticariogenic composition
EP0340171A2 (en) * 1988-04-27 1989-11-02 Warner-Lambert Company Cyclodextrin complexes of 5-aminohexahydropyrimidine compounds
EP0340171A3 (en) * 1988-04-27 1990-03-21 Warner-Lambert Company Cyclodextrin complexes of 5-aminohexahydropyrimidine compounds
GB2245830A (en) * 1990-06-12 1992-01-15 Ghomi Mina Safai Medicament and cosmetics for treating skin and hair conditions
GB2245830B (en) * 1990-06-12 1995-02-08 Ghomi Mina Safai Medicaments for treating skin comprising gum tragacanth

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