GB755676A - Improvements in or relating to the halogenation of phenols - Google Patents
Improvements in or relating to the halogenation of phenolsInfo
- Publication number
- GB755676A GB755676A GB12129/54A GB1212954A GB755676A GB 755676 A GB755676 A GB 755676A GB 12129/54 A GB12129/54 A GB 12129/54A GB 1212954 A GB1212954 A GB 1212954A GB 755676 A GB755676 A GB 755676A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenol
- ortho
- chloro
- ortho1
- para
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/62—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A process for producing a para-halophenol comprises reacting a phenol with a sulphonyl halide in the liquid phase in the presence of a metal halide at a temperature not in excess of 75 DEG C. The phenol may be one of the general formula <FORM:0755676/IV(a)/1> where Y is a hydrogen atom, a hydroxy group, an ether group such as an alkoxy or an aryloxy group, an alkyl group, an amino group or a mono- or di-substituted amino group, or an organic group containing amino, nitro, halo or hydroxy groups; a list of phenols which may be employed is given. The sulphuryl halide may be sulphuryl chloride, bromide, iodide or fluoride, and the metallic halide may be a chloride, bromide, iodide or fluoride of aluminium, iron, zinc, tin or titanium. Examples describe the preparation of 4-chloro-2-methyl phenol from ortho-cresol; para-chlorocatechol from catechol; 4-chloro-2-methoxy phenol from guaiacol; 4 - chloro - 2 - cyclohexoxy - phenol from ortho - cyclo - hexoxy - phenol; 4 - chloro-2 - cyclohexyl phenol from ortho - cyclohexyl phenol; 4 - chloro - 2 - aminophenol from ortho - amino - phenol; 4 - chloro - 2-(N - methylamino) phenol from ortho (N-methylamino) phenol; 4 - chloro - 2 - (diethylamino) phenol from ortho - (diethylamino) phenol; 4 - chloro - 2 - (dimethylaminoethoxy) phenol from ortho (dimethylaminoethoxy) phenol; ortho, ortho1 - oxy - di - para - chlorophenol from ortho - ortho1 - oxy - diphenol; ortho, ortho1 - ethylene - di - para - chlorophenol from ortho, ortho1 - ethylenediphenol; and 4 - chloro - 2 - (methylmercapto) phenol from ortho-methyl-mercapto-phenol. Metal halides used in the examples are ferric chloride and aluminium chloride. The preparation of 4-chloro-2-methyl-phenoxyacetic acid from 4-chloro-methyl phenol and monochloroacetic acid is also described.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US755676XA | 1953-04-27 | 1953-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB755676A true GB755676A (en) | 1956-08-22 |
Family
ID=22126602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12129/54A Expired GB755676A (en) | 1953-04-27 | 1954-04-27 | Improvements in or relating to the halogenation of phenols |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB755676A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1175690B (en) * | 1961-02-03 | 1964-08-13 | Ici Ltd | Process for the preparation of 4-chloro-2-methylphenol |
| CN114262263A (en) * | 2021-12-28 | 2022-04-01 | 河北美星化工有限公司 | Preparation method of 4-iodophenol |
-
1954
- 1954-04-27 GB GB12129/54A patent/GB755676A/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1175690B (en) * | 1961-02-03 | 1964-08-13 | Ici Ltd | Process for the preparation of 4-chloro-2-methylphenol |
| CN114262263A (en) * | 2021-12-28 | 2022-04-01 | 河北美星化工有限公司 | Preparation method of 4-iodophenol |
| CN114262263B (en) * | 2021-12-28 | 2024-04-19 | 河北美星化工有限公司 | Preparation method of 4-iodophenol |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB875954A (en) | Improvements in or relating to the production of polymeric material from monomeric epoxy compounds | |
| GB1415128A (en) | Halogenated 4-trifluoromethyl-4,-cyano-diphenyl-ethers process for their preparation and their use as herbicides | |
| GB1022744A (en) | New phenolic antimicrobial compositions | |
| GB755676A (en) | Improvements in or relating to the halogenation of phenols | |
| GB767400A (en) | Process for the manufacture of trialkylaluminium compounds | |
| US2777002A (en) | Para-halogenation of phenols | |
| GB1130113A (en) | Process for the production of bis(aminoalkyl)ethers | |
| FR2197849B1 (en) | ||
| Hine et al. | Methylene Derivatives as Intermediates in Polar Reactions. XIX. The Reaction of Potassium Isopropoxide with Chloroform, Bromoform and Dichlorofluoromethane1 | |
| GB804059A (en) | Improvements in the production of alkyl alkoxy aluminium halides, alkyl aryloxy aluminium halides and alkyl aluminium dihalides | |
| ES419331A1 (en) | Tris(cyclohexylalkyl)tin or hexakis(cyclohexylalkyl)tin compounds | |
| GB1451317A (en) | Preparation of phloroglucinol or its monomethyl ether | |
| GB1515700A (en) | Process for the manufacture of a polyether | |
| GB934909A (en) | New organic metallic compounds of aluminium and method for obtaining them | |
| GB936278A (en) | Process for the manufacture of phenols from diazonium salt solutions in a continuousmanner | |
| GB642997A (en) | Improvements in and relating to alkyl-substituted halogenosilanes | |
| GB494768A (en) | Aromatic polyether chlorides | |
| GB957987A (en) | Process for the production of trifluoromethylmercapto-phenols | |
| GB963902A (en) | Mono- or polyoxyethylated esters and their manufacture | |
| GB957581A (en) | Steroid compounds | |
| GB994506A (en) | A process for the preparation of aromatic mercapto compounds | |
| GB1036286A (en) | Organometallic compounds and substituted benzenes | |
| GB765527A (en) | New fluorinated anisoles and process for the manufacture thereof | |
| GB875464A (en) | Process for the production of hydroxyaryl-alkyl thioethers | |
| GB1000932A (en) | Method for producing monoalkyl ethers of dihydric phenols |