GB752707A - Process of producing 8-haloxanthine salts of ª -dimethylaminoethylbenzhydrylether - Google Patents

Process of producing 8-haloxanthine salts of ª -dimethylaminoethylbenzhydrylether

Info

Publication number
GB752707A
GB752707A GB1503154A GB1503154A GB752707A GB 752707 A GB752707 A GB 752707A GB 1503154 A GB1503154 A GB 1503154A GB 1503154 A GB1503154 A GB 1503154A GB 752707 A GB752707 A GB 752707A
Authority
GB
United Kingdom
Prior art keywords
haloxanthine
salts
dimethylaminoethyl
producing
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1503154A
Inventor
Olno Berg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farmaceutisk Industri AS
Original Assignee
Farmaceutisk Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutisk Industri AS filed Critical Farmaceutisk Industri AS
Priority to GB1503154A priority Critical patent/GB752707A/en
Publication of GB752707A publication Critical patent/GB752707A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for producing 8-haloxanthine salts of b -dimethylaminoethyl benzhydryl ether comprises a metathetical reaction between a solution of the neutral oxalate of b -dimethylaminoethyl benzhydryl ether and a solution of an alkali metal or ammonium salt of the 8-haloxanthine at a temperature of at least 90 DEG C. and separation of the salt thus formed. In examples the neutral oxalate of b -dimethylaminoethyl benzhydryl ether in alcoholic solution is reacted with (1) an aqueous solution of the ammonium salt of 8-bromotheophylline; (2) the sodium salt of 8-chlorotheophylline, the desired 8-haloxanthine salts crystallizing out. Potassium or lithium salts of the 8-haloxanthines can be reacted similarly.
GB1503154A 1954-05-21 1954-05-21 Process of producing 8-haloxanthine salts of ª -dimethylaminoethylbenzhydrylether Expired GB752707A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1503154A GB752707A (en) 1954-05-21 1954-05-21 Process of producing 8-haloxanthine salts of ª -dimethylaminoethylbenzhydrylether

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1503154A GB752707A (en) 1954-05-21 1954-05-21 Process of producing 8-haloxanthine salts of ª -dimethylaminoethylbenzhydrylether

Publications (1)

Publication Number Publication Date
GB752707A true GB752707A (en) 1956-07-11

Family

ID=10051828

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1503154A Expired GB752707A (en) 1954-05-21 1954-05-21 Process of producing 8-haloxanthine salts of ª -dimethylaminoethylbenzhydrylether

Country Status (1)

Country Link
GB (1) GB752707A (en)

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