GB751524A - -e-acyl lysines and their production - Google Patents

-e-acyl lysines and their production

Info

Publication number
GB751524A
GB751524A GB8134/54A GB813454A GB751524A GB 751524 A GB751524 A GB 751524A GB 8134/54 A GB8134/54 A GB 8134/54A GB 813454 A GB813454 A GB 813454A GB 751524 A GB751524 A GB 751524A
Authority
GB
United Kingdom
Prior art keywords
chloride
lysines
acyl
ammonia
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8134/54A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB751524A publication Critical patent/GB751524A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The Specification comprises (1) the production of e -acyl-lysines by saponifying caprolactam, acylating the resulting e -aminocaproic acid, chlorinating the e -acylaminocaproic acid and treating the chlorinated acid with ammonia, and (2) e -acyl-lysines of the formula R - CO - NH - (CH2)4 - CH(NH2)- COOH where R is an alkyl group of 2 or more carbon atoms. The chlorination step is carried out with sulphuryl chloride or a mixture thereof with thionyl chloride. The amination is preferably effected in the absence of iron, using an ammonia solution containing at least 50 per cent by weight of ammonia. Examples are given of the process using as acylating agents acetic anhydride, butyryl chloride, a -chlorobutyryl chloride, lauroyl chloride and adipoyl chloride, the corresponding N-acyl-lysines being recovered; the product from chlorobutyryl chloride is however aminobutyryl-lysine.ALSO:e -Acyl-lysines are used as food additives for cattle and poultry. A graph shows comparative results of the weight of chickens fed on vegetable protein (1) alone, (2) with methionine, and (3) with e -butyryl-lysine. Other compounds mentioned are e -acetyl, e -adipoyl, e -lauroyl and e -aminobutyryl-lysines.
GB8134/54A 1953-03-19 1954-03-19 -e-acyl lysines and their production Expired GB751524A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE751524X 1953-03-19

Publications (1)

Publication Number Publication Date
GB751524A true GB751524A (en) 1956-06-27

Family

ID=6652145

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8134/54A Expired GB751524A (en) 1953-03-19 1954-03-19 -e-acyl lysines and their production

Country Status (2)

Country Link
GB (1) GB751524A (en)
NL (2) NL95854C (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0255718A2 (en) * 1986-08-05 1988-02-10 Yeda Research And Development Company Limited Use of amphiphilic amide compounds in Z-type Langmuir-Blodgett films
WO1995028381A1 (en) * 1994-04-15 1995-10-26 Eastman Chemical Company Aqueous process for preparing amido-carboxylic acids by reacting an amino acid with a carboxylic acid anhydride

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0255718A2 (en) * 1986-08-05 1988-02-10 Yeda Research And Development Company Limited Use of amphiphilic amide compounds in Z-type Langmuir-Blodgett films
EP0255718A3 (en) * 1986-08-05 1989-04-12 Yeda Research And Development Company Limited Use of amphiphilic amide compounds in Z-type Langmuir-Blodgett films
US5047535A (en) * 1986-08-05 1991-09-10 Yeda Research And Development Company Limited N-heterocyclic amphiphilic amides
WO1995028381A1 (en) * 1994-04-15 1995-10-26 Eastman Chemical Company Aqueous process for preparing amido-carboxylic acids by reacting an amino acid with a carboxylic acid anhydride

Also Published As

Publication number Publication date
NL186062B (en)
NL95854C (en)

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