GB732415A - Process for the production of aroylated aminocarboxylic acids - Google Patents
Process for the production of aroylated aminocarboxylic acidsInfo
- Publication number
- GB732415A GB732415A GB16326/53A GB1632653A GB732415A GB 732415 A GB732415 A GB 732415A GB 16326/53 A GB16326/53 A GB 16326/53A GB 1632653 A GB1632653 A GB 1632653A GB 732415 A GB732415 A GB 732415A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aroylated
- acids
- alpha
- omega amino
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Aroylated aminocarboxylic acids are produced by heating an aroylated alpha or omega amino-substituted aliphatic carboxylic acid amide with water or an aqueous ammonia solution at elevated pressure and at a temperature above 100 DEG C., and preferably in the range 160-180 DEG C. By this treatment, hydrolytic cleavage of the aroylated alpha or omega amino-substituted aliphatic carboxylic acid amides of the general formula R.CO.NH.(CH2)nCONH2 occurs, the cleavage being substantially exclusively between the CO and NH2 groups of the acid amide, with the formation of aroylated alpha or omega amino-carboxylic acids. In the formula, R represents the aryl group and the number n is preferably not more than 11. The preferred quantities of water or aqueous ammonia are such that the amide is in solution at the reaction temperature. The acids are obtained from the final solution by acidification with mineral acids. In examples hippuric acid and delta-benzamido-n-valeric acid are obtained from their corresponding amides.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE732415X | 1952-07-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB732415A true GB732415A (en) | 1955-06-22 |
Family
ID=6639381
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB16326/53A Expired GB732415A (en) | 1952-07-12 | 1953-06-12 | Process for the production of aroylated aminocarboxylic acids |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB732415A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0046707A1 (en) * | 1980-08-27 | 1982-03-03 | Sanofi S.A. | Derivatives of 4-aminobutyric acid and the medicines especially active on the central nervous system containing them |
-
1953
- 1953-06-12 GB GB16326/53A patent/GB732415A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0046707A1 (en) * | 1980-08-27 | 1982-03-03 | Sanofi S.A. | Derivatives of 4-aminobutyric acid and the medicines especially active on the central nervous system containing them |
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