GB723159A - Steroids - Google Patents

Steroids

Info

Publication number
GB723159A
GB723159A GB17172/52A GB1717252A GB723159A GB 723159 A GB723159 A GB 723159A GB 17172/52 A GB17172/52 A GB 17172/52A GB 1717252 A GB1717252 A GB 1717252A GB 723159 A GB723159 A GB 723159A
Authority
GB
United Kingdom
Prior art keywords
progesterone
keto
dihydroxyprogesterone
propionyloxy
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB17172/52A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB723159A publication Critical patent/GB723159A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises 6 - acyloxy - 11 - keto-progesterones and the preparation thereof by reacting 6 - hydroxy - 11 - keto - progesterone with an esterifying agent, e.g., an organic carboxylic acid anhydride. Examples disclose the production of 6-acetoxy-, 6-formyloxy-, 6-propionyloxy-, 6-benzoxy-, and 6-(b -carboxy-propionyloxy) - 11 - keto - progesterone. 6,11a - dihydroxyprogesterone is obtained by the oxygenation of progesterone by means of a culture of the fungus Rhizopus arrhizus. 6-Hydroxy-11-keto-progesterone is obtained by oxidizing 6,11a -dihydroxyprogesterone with a chromic acid-acetic acid solution.
GB17172/52A 1952-04-01 1952-07-08 Steroids Expired GB723159A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US723159XA 1952-04-01 1952-04-01

Publications (1)

Publication Number Publication Date
GB723159A true GB723159A (en) 1955-02-02

Family

ID=22106832

Family Applications (1)

Application Number Title Priority Date Filing Date
GB17172/52A Expired GB723159A (en) 1952-04-01 1952-07-08 Steroids

Country Status (1)

Country Link
GB (1) GB723159A (en)

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