GB688211A - The manufacture of derivatives of amino acids - Google Patents

The manufacture of derivatives of amino acids

Info

Publication number
GB688211A
GB688211A GB19384/49A GB1938449A GB688211A GB 688211 A GB688211 A GB 688211A GB 19384/49 A GB19384/49 A GB 19384/49A GB 1938449 A GB1938449 A GB 1938449A GB 688211 A GB688211 A GB 688211A
Authority
GB
United Kingdom
Prior art keywords
acid
paraaminosalicyclic
derivatives
manufacture
benzaldehyde
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB19384/49A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ward Blenkinsop and Co Ltd
Original Assignee
Ward Blenkinsop and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ward Blenkinsop and Co Ltd filed Critical Ward Blenkinsop and Co Ltd
Priority to GB19384/49A priority Critical patent/GB688211A/en
Publication of GB688211A publication Critical patent/GB688211A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/64—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring the carbon skeleton being further substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises N - benzyl - paraaminosalicyclic acids in which the benzyl group may be substituted by one or two halogens, obtainable by the action of benzaldehyde or its mono- or di-halogen derivatives on p-aminosalicylic acid and either simultaneously or subsequently, reducing the product in presence of a hydrogenation catalyst. In examples, benzaldehyde reacts with paraaminosalicyclic acid in acetic acid/ethyl alcohol, and the mixture is reduced with hydrogen with palladium/charcoal to give the 4-benzylaminosalicylic acid; 4-chlorobenzaldehyde and 2 : 4-dichlorobenazldehyde give corresponding products. The intermediately-produced para-N-benzylidene compounds may be isolated.
GB19384/49A 1949-07-22 1949-07-22 The manufacture of derivatives of amino acids Expired GB688211A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB19384/49A GB688211A (en) 1949-07-22 1949-07-22 The manufacture of derivatives of amino acids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19384/49A GB688211A (en) 1949-07-22 1949-07-22 The manufacture of derivatives of amino acids

Publications (1)

Publication Number Publication Date
GB688211A true GB688211A (en) 1953-03-04

Family

ID=10128453

Family Applications (1)

Application Number Title Priority Date Filing Date
GB19384/49A Expired GB688211A (en) 1949-07-22 1949-07-22 The manufacture of derivatives of amino acids

Country Status (1)

Country Link
GB (1) GB688211A (en)

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