GB652277A - Process for the manufacture of organic amino diols - Google Patents

Process for the manufacture of organic amino diols

Info

Publication number
GB652277A
GB652277A GB13748/50A GB1374850A GB652277A GB 652277 A GB652277 A GB 652277A GB 13748/50 A GB13748/50 A GB 13748/50A GB 1374850 A GB1374850 A GB 1374850A GB 652277 A GB652277 A GB 652277A
Authority
GB
United Kingdom
Prior art keywords
nitrophenyl
reg
diol
hydrolysis
isolated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB13748/50A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parke Davis and Co LLC
Original Assignee
Parke Davis and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis and Co LLC filed Critical Parke Davis and Co LLC
Publication of GB652277A publication Critical patent/GB652277A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Aminodiols of the general formula <FORM:0652277/IV (b)/1> (wherein R3 represents hydrogen or an alkyl radical of not more than 4 carbon atoms, and R4 and R5 are the same or different and represent hydrogen, halogen, or alkyl or alkoxy radicals of not more than 4 carbon atoms) are manufactured by hydrolysing the corresponding triacylated compounds with an acidic or alkaline hydrolytic agent until all three acyl groups have been removed. The hydrolysis is preferably effected by means of aqueous mineral acid, whereby the product is obtained as a salt of the acid and may be isolated in this form or neutralized and isolated as the free base. The products exist as structural (regular and pseudo) and optical isomers. Examples describe the hydrolysis, with dilute hydrohalic acids, of the triacetyl derivatives of dl-#Y- and dl - reg. - 1 - p - nitrophenyl-, dl - #Y - 1 - o - methyl - p - nitrophenyl-, dl - #Y - 1 - m - methoxy - p - nitrophenyl-, dl - reg. - 1 - (21 - nitro - 41 : 51-dimethylphenyl)- and 1 - (21 - chloro - 51 - nitrophenyl) - 2 - aminopropane - 1 : 3-diol and of dl-#Y-2 - amino - 3 - p - nitrophenylbutane - 1 : 3 - diol. Specifications 652,272, 652,273, 652,274, 652,275, 652,276, 652,278, 652,279 and 652,280 are referred to.
GB13748/50A 1948-03-16 1948-12-15 Process for the manufacture of organic amino diols Expired GB652277A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US652277XA 1948-03-16 1948-03-16

Publications (1)

Publication Number Publication Date
GB652277A true GB652277A (en) 1951-04-18

Family

ID=22061212

Family Applications (1)

Application Number Title Priority Date Filing Date
GB13748/50A Expired GB652277A (en) 1948-03-16 1948-12-15 Process for the manufacture of organic amino diols

Country Status (1)

Country Link
GB (1) GB652277A (en)

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