GB616438A - Improvements in or relating to the treatment of streptomycin-containing colutions - Google Patents
Improvements in or relating to the treatment of streptomycin-containing colutionsInfo
- Publication number
- GB616438A GB616438A GB2632246A GB2632246A GB616438A GB 616438 A GB616438 A GB 616438A GB 2632246 A GB2632246 A GB 2632246A GB 2632246 A GB2632246 A GB 2632246A GB 616438 A GB616438 A GB 616438A
- Authority
- GB
- United Kingdom
- Prior art keywords
- streptomycin
- acid
- treatment
- effected
- exceeding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Compounds Of Unknown Constitution (AREA)
Abstract
Filtered crude or partially purified aqueous streptomycin-containing solutions, derived from a fermentation process utilizing an organism of the genus Actinomyces, are acidified to pH 0.5-4.5 (preferably 1.0-2.5) and maintained thereat at a temperature not exceeding 100 DEG C. (preferably not exceeding 60 DEG C.) until an increase in antibiotic potency has been effected, and thereafter the augmented amount of streptomycin is separated from solution. The treatment with acid is preferably terminated (e.g. by adjusting the pH of the solution to about 7) at or about the moment when the maximum antibiotic potency is attained, the time required to reach this point depending on the degree of acidity and the temperature employed. The acidification may be effected with sulphuric acid (preferred), hydrochloric acid or weaker acids such as acetic acid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2632246A GB616438A (en) | 1946-09-02 | 1946-09-02 | Improvements in or relating to the treatment of streptomycin-containing colutions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2632246A GB616438A (en) | 1946-09-02 | 1946-09-02 | Improvements in or relating to the treatment of streptomycin-containing colutions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB616438A true GB616438A (en) | 1949-01-21 |
Family
ID=10241836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2632246A Expired GB616438A (en) | 1946-09-02 | 1946-09-02 | Improvements in or relating to the treatment of streptomycin-containing colutions |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB616438A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2565402A (en) * | 1948-12-11 | 1951-08-21 | Pfizer & Co C | Streptomycin preparation |
| US2683142A (en) * | 1951-01-26 | 1954-07-06 | Merck & Co Inc | High ph dihydrostreptomycin and process therefor |
-
1946
- 1946-09-02 GB GB2632246A patent/GB616438A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2565402A (en) * | 1948-12-11 | 1951-08-21 | Pfizer & Co C | Streptomycin preparation |
| US2683142A (en) * | 1951-01-26 | 1954-07-06 | Merck & Co Inc | High ph dihydrostreptomycin and process therefor |
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