GB571049A - Manufacture of salts of n-dimethylacroyl-p-aminobenzene sulphonamide - Google Patents
Manufacture of salts of n-dimethylacroyl-p-aminobenzene sulphonamideInfo
- Publication number
- GB571049A GB571049A GB6058/43A GB605843A GB571049A GB 571049 A GB571049 A GB 571049A GB 6058/43 A GB6058/43 A GB 6058/43A GB 605843 A GB605843 A GB 605843A GB 571049 A GB571049 A GB 571049A
- Authority
- GB
- United Kingdom
- Prior art keywords
- salts
- bases
- dimethylacroyl
- manufacture
- diethylamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 2
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 abstract 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 abstract 2
- 239000000920 calcium hydroxide Substances 0.000 abstract 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 abstract 2
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 abstract 2
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 235000011121 sodium hydroxide Nutrition 0.000 abstract 1
- XRVJPLDTMUSSDE-UHFFFAOYSA-N sulfadicramide Chemical compound CC(C)=CC(=O)NS(=O)(=O)C1=CC=C(N)C=C1 XRVJPLDTMUSSDE-UHFFFAOYSA-N 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
N1-dimethylacroyl-p-aminobenzene sulphonamide is converted into salts by treatment with bases which have therapeutic properties and which are suitable for injection purposes. Bases specified include soda lye, calcium hydroxide and organic bases such as diethylamine and amino-ethanol. In examples, salts are prepared using as bases alcoholic sodium methylate, calcium hydroxide and diethylamine. Specifications 541,958 and 547966 are referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH571049X | 1942-04-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB571049A true GB571049A (en) | 1945-08-03 |
Family
ID=4520911
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB6058/43A Expired GB571049A (en) | 1942-04-16 | 1943-04-15 | Manufacture of salts of n-dimethylacroyl-p-aminobenzene sulphonamide |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB571049A (en) |
-
1943
- 1943-04-15 GB GB6058/43A patent/GB571049A/en not_active Expired
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