GB560681A - New substituted ureas - Google Patents
New substituted ureasInfo
- Publication number
- GB560681A GB560681A GB1426942A GB1426942A GB560681A GB 560681 A GB560681 A GB 560681A GB 1426942 A GB1426942 A GB 1426942A GB 1426942 A GB1426942 A GB 1426942A GB 560681 A GB560681 A GB 560681A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ethoxyethyl
- ethylenediamine
- carboxylic
- chloride
- piperidide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/14—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Bis-ureas, useful as respiratory stimulants, of the formula X-CO-NR-A-NR-CO-Y, where X and Y are radicals of dialkylamines or heterocyclic secondary amines of molecular weight not exceeding 120, the R's are alkoxyalkyl groups which jointly contain not more than 12 carbon atoms and A is an alkylene chain of 2 to 6 carbon atoms which may bear one or more alkyl, alkoxy or alkoxyalkyl substituents or two such chains united by -O-, -S-, -NH-, or -N.Alkyl-, are prepared by causing a monourea X-CO-NR-A-NHR to react with a carbamyl chloride Y-CO-Cl, or to react with phosgene to form the carbamyl chloride X-CO-NR-A-NR-CO-Cl which is then combined with an amine YH. The monoureas are prepared by combining one molecule of a diamine RNH-A-NHR with one molecule of a carbamyl chloride X-CO-Cl. In an example NN1-di-(b -ethoxyethyl) - ethylenediamine - N - carboxylic piperidide-N1-carboxylic dimethyl amide is prepared from dimethylcarbamyl chloride and NN1 - di - (b - ethoxyethyl) - ethylenediamine - N-carboxylic piperidide which is itself made along with a little NN1-di-(b -ethoxyethyl)-ethylenediamine - NN1 - dicarboxylic bis - piperidide from piperidine-N-carboxylic chloride and NN1 - di - (b - ethoxyethyl) - ethylenediamine. Specifications 560,680 and 560,699 are referred to.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1426942A GB560681A (en) | 1942-10-12 | 1942-10-12 | New substituted ureas |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1426942A GB560681A (en) | 1942-10-12 | 1942-10-12 | New substituted ureas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB560681A true GB560681A (en) | 1944-04-14 |
Family
ID=10038096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1426942A Expired GB560681A (en) | 1942-10-12 | 1942-10-12 | New substituted ureas |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB560681A (en) |
-
1942
- 1942-10-12 GB GB1426942A patent/GB560681A/en not_active Expired
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