GB434497A - Manufacture of acridinium compounds - Google Patents
Manufacture of acridinium compoundsInfo
- Publication number
- GB434497A GB434497A GB6845/34A GB684534A GB434497A GB 434497 A GB434497 A GB 434497A GB 6845/34 A GB6845/34 A GB 6845/34A GB 684534 A GB684534 A GB 684534A GB 434497 A GB434497 A GB 434497A
- Authority
- GB
- United Kingdom
- Prior art keywords
- diamino
- acridinium
- condensed
- acetone
- ketone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Abstract
New acridinium compounds are obtained by condensing a 3 : 6-diamino-10-alkyl or benzyl-acridinium compound with an aliphatic, hydro-aromatic or aliphatic-aromatic ketone in presence of caustic alkali. One of the amino groups reacts. The products are useful for the manufacture of pharmaceutical preparations. According to examples: (1) 3 : 6-diamino-10-methylacridinium chloride is condensed with acetone, or acetophenone; (2) the corresponding sulphate is condensed with cyclohexanone; (3) the corresponding 10-benzyl compound is condensed with acetone. Further specified acridinium-compounds include the bromide, and specified ketones include methylethyl ketone, diethylketone, methyl cyclohexanone, propiophenone, butyrophenone, tolylmethyl-ketone, methyl cyclohexanone and methyl propylketone. A sample has been furnished under Sect. 2 (5) of the product obtainable by condensing 2 : 7-dimethyl - 3 : 6 - diamino - 10 - methylacridinium chloride with acetone in alkaline solution. The Specification as open to inspection under Sect. 91 comprises also examples of the condensation of a 3:6-diamino-10-methylacridinium lactate and acetylacetone, and the use of salts such as the carbonate, bicarbonate, nitrate, tartrate, oxalate, glycollate, formate acetate and propionate of the acridinium compounds This subject-matter does not appear in the Specification as accepted. p
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE434497X | 1933-03-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB434497A true GB434497A (en) | 1935-09-03 |
Family
ID=6506525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6845/34A Expired GB434497A (en) | 1933-03-04 | 1934-03-03 | Manufacture of acridinium compounds |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB434497A (en) |
-
1934
- 1934-03-03 GB GB6845/34A patent/GB434497A/en not_active Expired
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