GB2554767A - Detecting and characterising a microorganism - Google Patents

Detecting and characterising a microorganism Download PDF

Info

Publication number
GB2554767A
GB2554767A GB1617353.6A GB201617353A GB2554767A GB 2554767 A GB2554767 A GB 2554767A GB 201617353 A GB201617353 A GB 201617353A GB 2554767 A GB2554767 A GB 2554767A
Authority
GB
United Kingdom
Prior art keywords
culture vessel
culture
clinical sample
microorganism
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB1617353.6A
Other languages
English (en)
Other versions
GB201617353D0 (en
Inventor
Jarvius Jonas
Lind Anders
Soderstrom Henrik
Grawé Jan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Q Linea AB
Original Assignee
Q Linea AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Q Linea AB filed Critical Q Linea AB
Publication of GB201617353D0 publication Critical patent/GB201617353D0/en
Priority to FR1753439A priority Critical patent/FR3050461A1/fr
Priority to US16/094,699 priority patent/US11845978B2/en
Priority to EP17719557.5A priority patent/EP3294057B1/en
Priority to PCT/EP2017/059542 priority patent/WO2017182645A1/en
Publication of GB2554767A publication Critical patent/GB2554767A/en
Priority to US18/385,099 priority patent/US12655465B2/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/146—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving
    • A01N1/148—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving with provisions specially adapted for transporting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/18—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Thermal Sciences (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Mechanical Engineering (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
GB1617353.6A 2016-04-21 2016-10-13 Detecting and characterising a microorganism Withdrawn GB2554767A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR1753439A FR3050461A1 (cg-RX-API-DMAC10.html) 2016-04-21 2017-04-20
US16/094,699 US11845978B2 (en) 2016-04-21 2017-04-21 Detecting and characterizing a microorganism
EP17719557.5A EP3294057B1 (en) 2016-04-21 2017-04-21 Detecting and characterising a microorganism
PCT/EP2017/059542 WO2017182645A1 (en) 2016-04-21 2017-04-21 Detecting and characterising a microorganism
US18/385,099 US12655465B2 (en) 2016-04-21 2023-10-30 System for detecting and characterizing a microorganism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB201606991 2016-04-21

Publications (2)

Publication Number Publication Date
GB201617353D0 GB201617353D0 (en) 2016-11-30
GB2554767A true GB2554767A (en) 2018-04-11

Family

ID=57680912

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1617353.6A Withdrawn GB2554767A (en) 2016-04-21 2016-10-13 Detecting and characterising a microorganism

Country Status (5)

Country Link
US (2) US11845978B2 (cg-RX-API-DMAC10.html)
EP (1) EP3294057B1 (cg-RX-API-DMAC10.html)
FR (1) FR3050461A1 (cg-RX-API-DMAC10.html)
GB (1) GB2554767A (cg-RX-API-DMAC10.html)
WO (1) WO2017182645A1 (cg-RX-API-DMAC10.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022178142A1 (en) * 2021-02-17 2022-08-25 CAP Diagnostics, LLC, dba Pathnostics Methods and systems for determining suitability of compositions for inhibiting growth of polymicrobial samples
US20210172000A1 (en) * 2017-04-19 2021-06-10 CAP Diagnostics, LLC, dba Pathnostics Methods and systems for preparing therapeutic solutions for polymicrobial infections
US11053532B2 (en) 2017-04-19 2021-07-06 CAP Diagnostics, LLC Methods for treating polymicrobial infections
EP3717657B1 (en) * 2017-11-30 2026-08-05 Ascilion AB A system for assessing microbial susceptibility to antibiotic agents
EP3731959B1 (en) 2017-12-29 2025-10-08 Clear Labs, Inc. Automated priming and library loading device
EP4111209A4 (en) * 2020-02-25 2025-07-16 Inst For Environmental Health Inc INCUBATOR ALLOWING ENRICHMENT DURING TRANSPORT
WO2024059305A1 (en) * 2022-09-15 2024-03-21 General Electric Company Method and apparatus for using lyophilized reagent beads for antimicrobial susceptibility testing
CN116218893B (zh) * 2023-03-24 2025-07-29 哈尔滨医科大学 一种通过体外扩增重组质粒在其编码基因上生成短片段串联重复序列的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0853658A1 (en) * 1995-09-29 1998-07-22 Idexx Laboratories, Inc. Self-contained incubator for growth of microorganism
WO2015189390A1 (en) * 2014-06-13 2015-12-17 Q-Linea Ab Method for detecting and characterising a microorganism
US20160053219A1 (en) * 2014-08-25 2016-02-25 Opgen, Inc. Systems, methods, and devices for temperature control

Family Cites Families (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159384A (en) 1962-07-02 1964-12-01 Bio Science Labor Agitator for laboratory tubes and flasks
US3764780A (en) 1971-06-16 1973-10-09 C Ellis Blood culture apparatus
US3975001A (en) 1973-10-19 1976-08-17 American Hospital Supply Corporation Apparatus for mixing fluids held in tubes
GB1507026A (en) * 1974-04-11 1978-04-12 Nat Res Dev Endoprosthetic devices
US4004883A (en) 1975-07-11 1977-01-25 G. D. Searle & Co. Sensing, leveling and mixing apparatus
DE7922217U1 (de) 1979-08-03 1979-11-22 Binz Gmbh & Co, 7073 Lorch Warmhaltebehaelter zum transport von infusionen o.dgl.
US4629686A (en) 1982-02-19 1986-12-16 Endotronics, Inc. Apparatus for delivering a controlled dosage of a chemical substance
JPS60501339A (ja) 1983-01-10 1985-08-22 ジエン−プロ−ブ　インコ−ポレィテッド 生物を検出、同定又は定量する方法およびキット
EP0122581B1 (en) 1983-04-15 1991-01-16 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Process for isolating bacteria in blood
US4666850A (en) 1983-10-28 1987-05-19 Becton, Dickinson And Company Microbial pathogen detecting system and process
US4652517A (en) 1984-06-11 1987-03-24 Diagnostic Research Limited Partnership Methods for the in vitro detection and identification of unknown pathogens or genetic entities
WO1988006189A1 (en) 1987-02-12 1988-08-25 Sdi Diagnostics, Inc. Test system, test device and method for detecting pathogenic organisms and antibiotic resistance genes in body fluids
US5217876A (en) 1988-03-15 1993-06-08 Akzo N.V. Method for detecting microorganisms
CA2016699C (en) 1989-05-15 2003-11-18 Paul N. Marshall Lytic agents and uses thereof
US6406844B1 (en) 1989-06-07 2002-06-18 Affymetrix, Inc. Very large scale immobilized polymer synthesis
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US6346413B1 (en) 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
US5183994A (en) 1990-10-26 1993-02-02 Bowles Sr Dale D Heated drug box
US5052812A (en) 1990-11-19 1991-10-01 New Brunswick Scientific Co., Inc. Bath shaker
US5316146A (en) 1991-03-06 1994-05-31 Ulster Scientific, Inc. Vial transporter
JP2565844B2 (ja) 1992-02-07 1996-12-18 アボツト・ラボラトリーズ 細胞溶解処理条件下で異種細胞集団を正確に計数し，感受性に関する格付けを行う方法
US5238302A (en) 1992-06-12 1993-08-24 Rohan Wilma M Vibrating mixer for nail polish and other liquids
US5882918A (en) 1995-08-08 1999-03-16 Genespan Corporation Cell culture incubator
SE9400522D0 (sv) 1994-02-16 1994-02-16 Ulf Landegren Method and reagent for detecting specific nucleotide sequences
DE69527585T2 (de) 1994-06-08 2003-04-03 Affymetrix, Inc. Verfahren und Vorrichtung zum Verpacken von Chips
US20020055101A1 (en) 1995-09-11 2002-05-09 Michel G. Bergeron Specific and universal probes and amplification primers to rapidly detect and identify common bacterial pathogens and antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
AU4586096A (en) 1995-03-10 1996-09-19 Becton Dickinson & Company Sample processing method for whole blood
JPH08285839A (ja) 1995-04-13 1996-11-01 Daiichi Kigyo:Kk 病理検体等運搬用容器
US5577837A (en) 1995-05-19 1996-11-26 Forma Scientific, Inc. Temperature controlled HEPA-filtered console shaker
US6096532A (en) 1995-06-07 2000-08-01 Aastrom Biosciences, Inc. Processor apparatus for use in a system for maintaining and growing biological cells
SE506908C2 (sv) 1995-09-08 1998-03-02 Ulf Landegren Inst F Medicinsk Medicinsk användning av padlockprober
US5994066A (en) 1995-09-11 1999-11-30 Infectio Diagnostic, Inc. Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
DK0862656T3 (da) 1995-11-21 2001-04-09 Univ Yale Unimolekylær segmentamplifikation og -detektering
DK0929809T3 (da) 1995-12-08 2000-08-28 Martin Raithel Fremgangsmåde og apparat til in vitro diagnose af allergiske lidelser
SE9601676D0 (sv) 1996-04-30 1996-04-30 Ulf Landegren Improved probing of specific mucleic acids
US5770394A (en) 1996-05-22 1998-06-23 Becton Dickinson And Company Method and apparatus for detecting bacteria using a blood culture froth
EP0822261B1 (en) 1996-07-29 2002-07-03 Academia Sinica Methods for rapid antimicrobial susceptibility testing
US5817508A (en) 1996-09-27 1998-10-06 Becton Dickinson And Company Blood culture apparatus having an auto-unloading and sorting device
WO1998029736A1 (en) 1996-12-31 1998-07-09 Genometrix Incorporated Multiplexed molecular analysis apparatus and method
US6255467B1 (en) 1997-11-06 2001-07-03 Pathobiotek Diagnostics Inc. Human blood bacterium
US6028293A (en) 1998-04-20 2000-02-22 Tcp Reliable Inc. Temperature-controlled container with heating means
US6059446A (en) 1998-05-08 2000-05-09 Dschida; William J. A. Apparatus for mixing the contents of microcentrifuge tubes
EP1137803A1 (en) 1998-12-11 2001-10-04 Visible Genetics Inc. Method and kit for the characterization of antibiotic-resistance mutations in mycobacterium tuberculosis
WO2000067037A2 (en) 1999-04-29 2000-11-09 Dade Microscan Inc. A combined rapid anti-microbial susceptibility assay and microorganism identification system
WO2000071675A1 (en) 1999-05-25 2000-11-30 Millipore Corporation Method for rapidly detecting and enumerating microorganisms in mammalian cell preparations using atp bioluminescence
WO2000072970A1 (en) 1999-05-28 2000-12-07 Cepheid Cartridge for conducting a chemical reaction
JP2001103981A (ja) 1999-08-03 2001-04-17 Nisshinbo Ind Inc 結核菌診断キット
US6465448B1 (en) 1999-08-13 2002-10-15 Case Western Reserve University Methoxyamine potentiation of temozolomide anti-cancer activity
JP2001169778A (ja) 1999-12-17 2001-06-26 Joji Oshima 迅速細菌遺伝子検査法及びキット
CN2436459Y (zh) 2000-08-14 2001-06-27 青岛市家用电器研究所 一种血液运输用储藏箱
US20040121309A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
WO2004060278A2 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
WO2002072264A1 (en) 2001-03-09 2002-09-19 Biomicro Systems, Inc. Method and system for microfluidic interfacing to arrays
US7008788B2 (en) 2001-07-30 2006-03-07 Agilent Technologies, Inc. Containers for supports comprising biopolymers
US6803208B2 (en) 2001-07-30 2004-10-12 The United States Of America As Represented By The Secretary Of The Navy Automated epifluorescence microscopy for detection of bacterial contamination in platelets
GB2378245A (en) 2001-08-03 2003-02-05 Mats Nilsson Nucleic acid amplification method
ATE437216T1 (de) 2001-09-06 2009-08-15 Genomic Profiling Systems Inc Schnellnachweis replizierender zellen
US20030098271A1 (en) 2001-11-26 2003-05-29 Ralph Somack Capsule and tray systems for combined sample collection, archiving, purification, and PCR
DE10201463B4 (de) 2002-01-16 2005-07-21 Clondiag Chip Technologies Gmbh Reaktionsgefäß zur Durchführung von Array-Verfahren
RU2228735C2 (ru) 2002-04-10 2004-05-20 Абанин Вячеслав Владимирович Устройство для хранения концентрата тромбоцитов
EP1527172B1 (en) 2002-05-17 2008-11-26 Molzym GmbH & Co. KG Method for nucleic acid extraction and nucleic acid purification
DE10222133A1 (de) 2002-05-17 2003-12-04 Gl Biotech Gmbh Verfahren zur Nukleinsäure-Extraktion und Nukleinsäure-Reinigung
US20060094034A1 (en) 2003-04-30 2006-05-04 Roland Brousseau Virulence and antibiotic resistance array and uses thereof
EP1627082B1 (en) 2003-05-13 2009-07-15 Gen-Probe Incorporated Method and kit for identifying antibiotic-resistant microorganisms
ES2661168T3 (es) 2003-07-12 2018-03-27 Accelerate Diagnostics, Inc. Biodetección sensible y rápida
US20120077206A1 (en) 2003-07-12 2012-03-29 Accelr8 Technology Corporation Rapid Microbial Detection and Antimicrobial Susceptibility Testing
US7341841B2 (en) 2003-07-12 2008-03-11 Accelr8 Technology Corporation Rapid microbial detection and antimicrobial susceptibility testing
US7205111B2 (en) * 2003-07-24 2007-04-17 Marshfield Clinic Rapid identification of bacteria from positive blood cultures
US20050042144A1 (en) 2003-08-18 2005-02-24 A. Robert Hubbard Portable insulated container for biological specimens
EP1672971B1 (en) 2003-09-12 2017-11-01 National Institute of Advanced Industrial Science and Technology Method for manufacturing a substrate
DE602004019564D1 (de) 2003-12-09 2009-04-02 Bio Merieux Inc Verfahren zum nachweis bakterieller krankheitserreger
US7429464B2 (en) 2003-12-09 2008-09-30 Biomerieux, Inc. Methods for detecting bacterial pathogens
EP1574583A1 (en) 2004-03-10 2005-09-14 Roche Diagnostics GmbH Methods for isolation of bacteria from biological samples
CA2559943A1 (en) 2004-03-15 2005-10-06 Purdue Research Foundation Cell concentration and pathogen recovery
US7580920B2 (en) 2004-07-22 2009-08-25 Microsoft Corporation System and method for graceful degradation of a database query
US7662562B2 (en) 2004-08-10 2010-02-16 Becton, Dickinson And Company Method for rapid identification of microorganisms
DE102005009479A1 (de) 2005-03-02 2006-09-07 Molzym Gmbh & Co. Kg Verwendung von Nukleasen zum Abbau von Nukleinsäure in Gegenwart von chaotropen Agenzien und/oder Tensiden
WO2006105285A1 (en) 2005-03-31 2006-10-05 Hamilton Thorne Biosciences, Inc. Circularizable nucleic acid probes and amplification methods
US8074465B2 (en) 2005-09-12 2011-12-13 Genzyme Corporation Thermally insulated transport container for cell-based products and related methods
CA2622439A1 (en) 2005-09-15 2007-03-29 Microphage Incorporated Method and apparatus for identification of microorganisms using bacteriophage
US8017360B2 (en) 2005-11-10 2011-09-13 Panomics, Inc. Detection of nucleic acids through amplification of surrogate nucleic acids
US20090209031A1 (en) 2006-01-26 2009-08-20 Tyco Healthcare Group Lp Medical device package
US7334516B2 (en) 2006-03-08 2008-02-26 Taiwan Supercritical Technology Co., Ltd. Aging device for liquor or wine
EP2345740B1 (en) 2006-06-06 2015-09-30 Gen-Probe Incorporated Tagged oligonucleotides and their use in nucleic acid amplification methods
EP2049646A2 (en) 2006-07-14 2009-04-22 Xcellerex, Inc. Environmental containment systems
JP4872511B2 (ja) 2006-08-02 2012-02-08 株式会社日立製作所 温度調整部材
ATE517192T1 (de) 2006-08-10 2011-08-15 Merck Patent Gmbh Verfahren zur isolierung von zellen
US8652782B2 (en) 2006-09-12 2014-02-18 Longhorn Vaccines & Diagnostics, Llc Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids
US20080145919A1 (en) * 2006-12-18 2008-06-19 Franklin Thomas D Portable organ and tissue preservation apparatus, kit and methods
CA2684311A1 (en) 2007-04-18 2008-10-30 Cornell University Microorganism detection method and apparatus
CN101130808B (zh) 2007-07-27 2011-08-17 南京市胸科医院 分枝杆菌快速培养药敏及鉴定微量检测法及装置
US8481265B2 (en) 2007-08-02 2013-07-09 Universite Laval Concentration and enrichment of microbial cells and microbial nucleic acids from bodily fluids
DE102007041864B4 (de) 2007-09-04 2012-05-03 Sirs-Lab Gmbh Verfahren zum Nachweis von Bakterien und Pilzen
EP2056114A1 (en) 2007-10-29 2009-05-06 Koninklijke Philips Electronics N.V. Automatic detection of infectious diseases
EP2087934A1 (de) 2008-02-07 2009-08-12 Qiagen GmbH Verfahren und Vorrichtung zur automatisierten Prozessierung einer Probe
DE102008029356A1 (de) 2008-06-20 2009-12-24 Siemens Healthcare Diagnostics Gmbh Verfahren zur Aufreinigung von Nukleinsäuren, insbesondere aus fixiertem Gewebe
US8512975B2 (en) 2008-07-24 2013-08-20 Biomerieux, Inc. Method for detection and characterization of a microorganism in a sample using time dependent spectroscopic measurements
WO2010048511A1 (en) 2008-10-24 2010-04-29 Becton, Dickinson And Company Antibiotic susceptibility profiling methods
MX2011004169A (es) 2008-10-31 2011-09-27 Bio Merieux Inc Metodos para la separacion y caracterizacion de microorganismos utilizando agentes identificadores.
WO2010062350A1 (en) * 2008-10-31 2010-06-03 Biomerieux, Inc. Methods for detection, characterization and/or identification of microorganisms in a sealed container
US8652800B2 (en) 2008-10-31 2014-02-18 Biomerieux, Inc. Method for separation, characterization and/or identification of microorganisms using spectroscopy
DK200801722A (en) 2008-12-05 2010-06-06 Unisensor As Optical sectioning of a sample and detection of particles in a sample
CN101745440B (zh) 2008-12-09 2012-01-25 北京量质科技有限公司 孵育室及包容运动式孵育装置
CN102460183B (zh) 2009-05-15 2015-04-15 生物梅里埃有限公司 用于微生物检测设备的自动化加载机构
CA2760982C (en) 2009-05-15 2019-01-15 Biomerieux, Inc. System and methods for rapid identification and/or characterization of a microbial agent in a sample
WO2011019874A1 (en) 2009-08-12 2011-02-17 President And Fellows Of Harvard College Biodetection methods and compositions
EP2325312A1 (de) 2009-11-19 2011-05-25 Qiagen GmbH Verfahren zur selektiven Anreicherung und Isolierung mikrobieller und optional zusätzlich viraler Nukleinsäuren
EP2333105A1 (en) 2009-12-08 2011-06-15 Koninklijke Philips Electronics N.V. Selective lysis of cells
AU2011220736C1 (en) 2010-02-24 2014-12-18 The Broad Institute, Inc Methods of diagnosing infectious disease pathogens and their drug sensitivity
DE102010012790B4 (de) 2010-03-25 2015-08-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Inkubatoreinrichtung und Verfahren zu deren Betrieb
CN101845390B (zh) 2010-04-30 2013-09-11 武汉迪艾斯科技有限公司 自动化细菌培养仪
EP2388312A1 (en) 2010-05-17 2011-11-23 Curetis AG Universally applicable lysis buffer and processing methods for the lysis of bodily samples
US20130261196A1 (en) 2010-06-11 2013-10-03 Lisa Diamond Nucleic Acids For Multiplex Organism Detection and Methods Of Use And Making The Same
ES2802649T3 (es) 2010-07-20 2021-01-20 Bio Merieux Inc Disposición de detector para botellas de cultivo de sangre con sensores colorimétricos
JP5767336B2 (ja) * 2010-11-04 2015-08-19 日立化成株式会社 全血の生体外刺激のための持ち運び可能な装置
EP2710127A4 (en) 2011-05-20 2014-12-03 Advandx Inc SELECTIVE ULTRASONIC LYSE OF BLOOD AND OTHER BIOLOGICAL FLUIDS AND WOVEN
CA2831969A1 (en) 2011-06-06 2012-12-30 Biocartis S.A. Selective lysis of cells by ionic surfactants
US10774300B2 (en) 2011-07-22 2020-09-15 Biomerieux, Inc. Methods and kits for isolating microorganisms from culture
US8603769B2 (en) 2011-10-07 2013-12-10 Becton, Dickinson And Company Method for direct and rapid identification of microorganisms and antimicrobial susceptibility testing from positive blood cultures
CA2863121A1 (en) 2011-12-30 2013-07-04 Abbott Molecular Inc. Microorganism nucleic acid purification from host samples
US10475527B2 (en) 2012-03-22 2019-11-12 Biomerieux, Inc. Method and system for detection of microbial growth in a specimen container
WO2013163210A1 (en) 2012-04-23 2013-10-31 Philip Alexander Rolfe Method and system for detection of an organism
JP6018808B2 (ja) 2012-06-12 2016-11-02 株式会社日立ハイテクノロジーズ 微生物検査方法および検査システム
EP2684947A1 (en) 2012-07-09 2014-01-15 Biocartis SA A method for filtering a biological sample
CA2923795A1 (en) 2012-09-10 2014-03-13 Accelerate Diagnostics, Inc. Same-day blood culture with digital microscopy
US10174366B2 (en) 2012-11-14 2019-01-08 Olink Bioscience Ab Localised RCA-based amplification method
WO2014160352A1 (en) 2013-03-13 2014-10-02 Abbott Molecular Inc. Target sequence enrichment
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
GB201321123D0 (en) 2013-11-29 2014-01-15 Linea Ab Q Amplification of circular molecules
GB2520765A (en) 2013-12-02 2015-06-03 Vanadis Diagnostics Ab Multiplex detection of nucleic acids
EP2942394A1 (en) 2014-05-09 2015-11-11 Molzym GmbH & Co. KG New method for isolating microbial DNA
CN204255722U (zh) 2014-12-15 2015-04-08 王东生 血液孵育器
EP3842148B1 (en) 2015-01-26 2026-03-25 Ventana Medical Systems, Inc. Tissue sample transport and storage assembly
WO2016168803A1 (en) * 2015-04-17 2016-10-20 Vax-Immune, LLC Portable disposable re-usable culture device for rapid diagnosis of infectious agents
GB201507026D0 (en) * 2015-04-24 2015-06-10 Linea Ab Q Medical sample transportation container
GB201511129D0 (en) 2015-06-24 2015-08-05 Linea Ab Q Method of determining antimicrobial susceptibility of a microorganism
US10407659B2 (en) * 2015-11-09 2019-09-10 Sahar M. H Jaffal Mini-incubator carrier box “Mini-incubator”

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0853658A1 (en) * 1995-09-29 1998-07-22 Idexx Laboratories, Inc. Self-contained incubator for growth of microorganism
WO2015189390A1 (en) * 2014-06-13 2015-12-17 Q-Linea Ab Method for detecting and characterising a microorganism
US20160053219A1 (en) * 2014-08-25 2016-02-25 Opgen, Inc. Systems, methods, and devices for temperature control

Also Published As

Publication number Publication date
EP3294057A1 (en) 2018-03-21
FR3050461A1 (cg-RX-API-DMAC10.html) 2017-10-27
GB201617353D0 (en) 2016-11-30
US20190119724A1 (en) 2019-04-25
WO2017182645A1 (en) 2017-10-26
US12655465B2 (en) 2026-06-16
EP3294057B1 (en) 2018-12-12
US11845978B2 (en) 2023-12-19
US20240368670A1 (en) 2024-11-07

Similar Documents

Publication Publication Date Title
US20240368670A1 (en) System for detecting and characterizing a microorganism
US11505835B2 (en) Method for determining the identity and antimicrobial susceptibility of a microorganism
US12203125B2 (en) Device for determining antimicrobial susceptibility of a microorganism
EP3405559B1 (en) Rapid antimicrobial susceptibility testing using high-sensitivity direct detection methods
JP5595415B2 (ja) 分析を目的とするサンプル内に存在する微生物の溶解、ならびにこの微生物の核酸の抽出および精製のための自動システム
CN105734169A (zh) 粗基质中的核酸的检测
WO2019073025A1 (en) METHOD FOR DETERMINING THE CONCENTRATION IN INTACT MICROORGANISMS IN A SAMPLE
WO2014100456A1 (en) Target capture system
CN103476945A (zh) 使用基于分子核酸的技术确定细胞活性的改进方法
WO2022271860A2 (en) Method for broad analysis of microorganisms and drug-resistance determinants in samples from a subject and devices therefor
Xu et al. Single-tube multiplex nested PCR system for efficient detection of pathogenic microorganisms in SPF rodents
WO2018222907A1 (en) Phage-mediated molecular detection methods and related aspects
Class et al. Patent application title: Methods for Detection of Micro-Organisms Inventors: Christopher John Stanley (Cambridge, GB) Stuart Wilson (London, GB) Assignees: MICROSEN MEDTECH LIMITED
CN108504723A (zh) 一种用于检测细菌mcr-1基因的引物组合物及应用

Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)