GB2504622B - Method and apparatus for improved resolution chromatography - Google Patents

Method and apparatus for improved resolution chromatography

Info

Publication number
GB2504622B
GB2504622B GB1314565.1A GB201314565A GB2504622B GB 2504622 B GB2504622 B GB 2504622B GB 201314565 A GB201314565 A GB 201314565A GB 2504622 B GB2504622 B GB 2504622B
Authority
GB
United Kingdom
Prior art keywords
improved resolution
resolution chromatography
chromatography
improved
resolution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1314565.1A
Other languages
English (en)
Other versions
GB201314565D0 (en
GB2504622A (en
Inventor
Harald Ritchie
Ross Andrew Shalliker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Western Sydney
Thermo Electron Manufacturing Ltd
Original Assignee
University of Western Sydney
Thermo Electron Manufacturing Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Western Sydney, Thermo Electron Manufacturing Ltd filed Critical University of Western Sydney
Priority to GB1314565.1A priority Critical patent/GB2504622B/en
Publication of GB201314565D0 publication Critical patent/GB201314565D0/en
Publication of GB2504622A publication Critical patent/GB2504622A/en
Application granted granted Critical
Publication of GB2504622B publication Critical patent/GB2504622B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/24—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the treatment of the fractions to be distributed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6017—Fluid distributors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/603—Construction of the column end pieces retaining the stationary phase, e.g. Frits
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6086—Construction of the column body form designed to optimise dispersion
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/80—Fraction collectors
GB1314565.1A 2011-05-26 2011-05-26 Method and apparatus for improved resolution chromatography Active GB2504622B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1314565.1A GB2504622B (en) 2011-05-26 2011-05-26 Method and apparatus for improved resolution chromatography

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1314565.1A GB2504622B (en) 2011-05-26 2011-05-26 Method and apparatus for improved resolution chromatography
GB1108859.8A GB2491168B (en) 2011-05-26 2011-05-26 Method and apparatus for improved resolution chromatography

Publications (3)

Publication Number Publication Date
GB201314565D0 GB201314565D0 (en) 2013-09-25
GB2504622A GB2504622A (en) 2014-02-05
GB2504622B true GB2504622B (en) 2015-09-16

Family

ID=44279655

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1314565.1A Active GB2504622B (en) 2011-05-26 2011-05-26 Method and apparatus for improved resolution chromatography
GB1108859.8A Active GB2491168B (en) 2011-05-26 2011-05-26 Method and apparatus for improved resolution chromatography

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1108859.8A Active GB2491168B (en) 2011-05-26 2011-05-26 Method and apparatus for improved resolution chromatography

Country Status (6)

Country Link
JP (1) JP6002212B2 (de)
CN (1) CN103687654B (de)
AU (1) AU2012260981B2 (de)
DE (1) DE112012002247B4 (de)
GB (2) GB2504622B (de)
WO (1) WO2012160032A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016128316A1 (en) * 2015-02-09 2016-08-18 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Means and methods for minimizing swept and dead volumes in chromatographic applications
CN104849378B (zh) * 2015-04-29 2017-03-15 华东理工大学 利用变径填充柱增加开管柱上样量的毛细管柱系统
JP6828755B2 (ja) * 2017-02-13 2021-02-10 株式会社島津製作所 超臨界流体装置
CN109406689B (zh) * 2018-10-22 2023-05-12 南京国科精准医学科技有限公司 一种离子渗透气体分子分离方法及装置
WO2023180977A1 (en) * 2022-03-23 2023-09-28 Kashiv Biosciences, Llc An improved process for the separation and analysis of pancreatic enzymes

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6263857A (ja) * 1985-09-13 1987-03-20 Japan Spectroscopic Co 流体中成分の分離分析方法及び装置

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UST959004I4 (en) * 1976-05-26 1977-06-07 E. I. Du Pont De Nemours And Company Chromatographic liquid dispensing inlet and method
JPS54139596A (en) * 1978-04-20 1979-10-30 Shimadzu Corp Liquid chromatography
US4537217A (en) 1982-12-09 1985-08-27 Research Triangle Institute Fluid distributor
JPH037815Y2 (de) * 1984-10-05 1991-02-26
JPS6253857A (ja) * 1985-08-31 1987-03-09 Fujitsu Ltd プリンタの印字濃度制御方式
US5124133A (en) * 1985-10-31 1992-06-23 Wilmer Schoenrock Apparatus and method for providing a uniform flow profile through large diameter, low-pressure vessels
JPS62240857A (ja) 1986-04-14 1987-10-21 Kurita Water Ind Ltd クロマトグラフイ装置
CS259190B1 (en) 1986-08-21 1988-10-14 Bedrich Porsch Column for preparative liquid chromatography
US4915843A (en) * 1988-11-28 1990-04-10 Union Oil Company Of California Continuous displacement chromatographic method
JPH0776767B2 (ja) 1988-12-10 1995-08-16 株式会社日立製作所 液体クロマトグラフイー用カラム
US4999102A (en) 1988-12-16 1991-03-12 The Amalgamated Sugar Company Liquid transfer manifold system for maintaining plug flow
JP3975575B2 (ja) * 1998-09-11 2007-09-12 株式会社島津製作所 カラム
CN101206205B (zh) * 2006-12-22 2011-08-10 中国科学院大连化学物理研究所 微流量液相色谱在线大体积进样的方法和专用装置

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6263857A (ja) * 1985-09-13 1987-03-20 Japan Spectroscopic Co 流体中成分の分離分析方法及び装置

Also Published As

Publication number Publication date
CN103687654A (zh) 2014-03-26
DE112012002247T5 (de) 2014-04-10
GB2491168B (en) 2014-09-10
GB2491168A (en) 2012-11-28
JP2014517924A (ja) 2014-07-24
GB201314565D0 (en) 2013-09-25
AU2012260981B2 (en) 2015-09-10
DE112012002247B4 (de) 2022-05-05
GB201108859D0 (en) 2011-07-06
CN103687654B (zh) 2016-03-16
JP6002212B2 (ja) 2016-10-05
WO2012160032A1 (en) 2012-11-29
GB2504622A (en) 2014-02-05

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