GB2491168B - Method and apparatus for improved resolution chromatography - Google Patents
Method and apparatus for improved resolution chromatographyInfo
- Publication number
- GB2491168B GB2491168B GB1108859.8A GB201108859A GB2491168B GB 2491168 B GB2491168 B GB 2491168B GB 201108859 A GB201108859 A GB 201108859A GB 2491168 B GB2491168 B GB 2491168B
- Authority
- GB
- United Kingdom
- Prior art keywords
- improved resolution
- resolution chromatography
- chromatography
- improved
- resolution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/24—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the treatment of the fractions to be distributed
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6004—Construction of the column end pieces
- G01N30/6017—Fluid distributors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6004—Construction of the column end pieces
- G01N30/603—Construction of the column end pieces retaining the stationary phase, e.g. Frits
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6052—Construction of the column body
- G01N30/6086—Construction of the column body form designed to optimise dispersion
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/80—Fraction collectors
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1314565.1A GB2504622B (en) | 2011-05-26 | 2011-05-26 | Method and apparatus for improved resolution chromatography |
GB1108859.8A GB2491168B (en) | 2011-05-26 | 2011-05-26 | Method and apparatus for improved resolution chromatography |
PCT/EP2012/059397 WO2012160032A1 (en) | 2011-05-26 | 2012-05-21 | Method and apparatus for improved resolution chromatography |
AU2012260981A AU2012260981B2 (en) | 2011-05-26 | 2012-05-21 | Method and apparatus for improved resolution chromatography |
DE112012002247.5T DE112012002247B4 (en) | 2011-05-26 | 2012-05-21 | Method and apparatus for enhanced resolution chromatography |
JP2014511834A JP6002212B2 (en) | 2011-05-26 | 2012-05-21 | Chromatographic method and apparatus with improved resolution |
CN201280025663.8A CN103687654B (en) | 2011-05-26 | 2012-05-21 | For improvement of the chromatographic method and apparatus of resolution ratio |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1108859.8A GB2491168B (en) | 2011-05-26 | 2011-05-26 | Method and apparatus for improved resolution chromatography |
Publications (3)
Publication Number | Publication Date |
---|---|
GB201108859D0 GB201108859D0 (en) | 2011-07-06 |
GB2491168A GB2491168A (en) | 2012-11-28 |
GB2491168B true GB2491168B (en) | 2014-09-10 |
Family
ID=44279655
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1314565.1A Active GB2504622B (en) | 2011-05-26 | 2011-05-26 | Method and apparatus for improved resolution chromatography |
GB1108859.8A Active GB2491168B (en) | 2011-05-26 | 2011-05-26 | Method and apparatus for improved resolution chromatography |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1314565.1A Active GB2504622B (en) | 2011-05-26 | 2011-05-26 | Method and apparatus for improved resolution chromatography |
Country Status (6)
Country | Link |
---|---|
JP (1) | JP6002212B2 (en) |
CN (1) | CN103687654B (en) |
AU (1) | AU2012260981B2 (en) |
DE (1) | DE112012002247B4 (en) |
GB (2) | GB2504622B (en) |
WO (1) | WO2012160032A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107209155A (en) * | 2015-02-09 | 2017-09-26 | 马克斯-普朗克科学促进学会 | For minimizing the apparatus and method scanned in chromatographic applications with dead volume |
CN104849378B (en) * | 2015-04-29 | 2017-03-15 | 华东理工大学 | The capillary column system for increasing open tubular column applied sample amount using reducing packed column |
WO2018146826A1 (en) * | 2017-02-13 | 2018-08-16 | 株式会社島津製作所 | Supercritical fluid device |
CN109406689B (en) * | 2018-10-22 | 2023-05-12 | 南京国科精准医学科技有限公司 | Ion permeation gas molecular separation method and device |
WO2023180977A1 (en) * | 2022-03-23 | 2023-09-28 | Kashiv Biosciences, Llc | An improved process for the separation and analysis of pancreatic enzymes |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6263857A (en) * | 1985-09-13 | 1987-03-20 | Japan Spectroscopic Co | Method and instrument for separating and analyzing component in fluid |
EP0371648A1 (en) * | 1988-11-28 | 1990-06-06 | Union Oil Company Of California | A continuous displacement chromatographic method and apparatus |
US5124133A (en) * | 1985-10-31 | 1992-06-23 | Wilmer Schoenrock | Apparatus and method for providing a uniform flow profile through large diameter, low-pressure vessels |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UST959004I4 (en) * | 1976-05-26 | 1977-06-07 | E. I. Du Pont De Nemours And Company | Chromatographic liquid dispensing inlet and method |
JPS54139596A (en) * | 1978-04-20 | 1979-10-30 | Shimadzu Corp | Liquid chromatography |
US4537217A (en) | 1982-12-09 | 1985-08-27 | Research Triangle Institute | Fluid distributor |
JPH037815Y2 (en) * | 1984-10-05 | 1991-02-26 | ||
JPS6253857A (en) * | 1985-08-31 | 1987-03-09 | Fujitsu Ltd | Printing density control system of printer |
JPS62240857A (en) | 1986-04-14 | 1987-10-21 | Kurita Water Ind Ltd | Chromatography apparatus |
CS259190B1 (en) * | 1986-08-21 | 1988-10-14 | Bedrich Porsch | Column for preparative liquid chromatography |
JPH0776767B2 (en) * | 1988-12-10 | 1995-08-16 | 株式会社日立製作所 | Column for liquid chromatography |
US4999102A (en) | 1988-12-16 | 1991-03-12 | The Amalgamated Sugar Company | Liquid transfer manifold system for maintaining plug flow |
JP3975575B2 (en) * | 1998-09-11 | 2007-09-12 | 株式会社島津製作所 | column |
CN101206205B (en) * | 2006-12-22 | 2011-08-10 | 中国科学院大连化学物理研究所 | Method and isolated device for micro flux liquid chromatogram on-line large volume sample injection |
-
2011
- 2011-05-26 GB GB1314565.1A patent/GB2504622B/en active Active
- 2011-05-26 GB GB1108859.8A patent/GB2491168B/en active Active
-
2012
- 2012-05-21 DE DE112012002247.5T patent/DE112012002247B4/en active Active
- 2012-05-21 AU AU2012260981A patent/AU2012260981B2/en active Active
- 2012-05-21 WO PCT/EP2012/059397 patent/WO2012160032A1/en active Application Filing
- 2012-05-21 JP JP2014511834A patent/JP6002212B2/en active Active
- 2012-05-21 CN CN201280025663.8A patent/CN103687654B/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6263857A (en) * | 1985-09-13 | 1987-03-20 | Japan Spectroscopic Co | Method and instrument for separating and analyzing component in fluid |
US5124133A (en) * | 1985-10-31 | 1992-06-23 | Wilmer Schoenrock | Apparatus and method for providing a uniform flow profile through large diameter, low-pressure vessels |
EP0371648A1 (en) * | 1988-11-28 | 1990-06-06 | Union Oil Company Of California | A continuous displacement chromatographic method and apparatus |
Also Published As
Publication number | Publication date |
---|---|
DE112012002247B4 (en) | 2022-05-05 |
JP6002212B2 (en) | 2016-10-05 |
WO2012160032A1 (en) | 2012-11-29 |
GB2491168A (en) | 2012-11-28 |
GB201314565D0 (en) | 2013-09-25 |
CN103687654A (en) | 2014-03-26 |
GB2504622B (en) | 2015-09-16 |
GB2504622A (en) | 2014-02-05 |
DE112012002247T5 (en) | 2014-04-10 |
JP2014517924A (en) | 2014-07-24 |
CN103687654B (en) | 2016-03-16 |
AU2012260981B2 (en) | 2015-09-10 |
GB201108859D0 (en) | 2011-07-06 |
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