GB2497105B - Process for the preparation of porous silica particles - Google Patents

Process for the preparation of porous silica particles

Info

Publication number
GB2497105B
GB2497105B GB1120665.3A GB201120665A GB2497105B GB 2497105 B GB2497105 B GB 2497105B GB 201120665 A GB201120665 A GB 201120665A GB 2497105 B GB2497105 B GB 2497105B
Authority
GB
United Kingdom
Prior art keywords
preparation
silica particles
porous silica
porous
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1120665.3A
Other languages
English (en)
Other versions
GB201120665D0 (en
GB2497105A (en
Inventor
Harald Ritchie
Adham Ahmed
Peter Myers
Haifei Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Electron Manufacturing Ltd
Original Assignee
Thermo Electron Manufacturing Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB1404340.0A priority Critical patent/GB2508554B/en
Application filed by Thermo Electron Manufacturing Ltd filed Critical Thermo Electron Manufacturing Ltd
Priority to GB1120665.3A priority patent/GB2497105B/en
Publication of GB201120665D0 publication Critical patent/GB201120665D0/en
Priority to JP2014543843A priority patent/JP6122438B2/ja
Priority to EP12794688.7A priority patent/EP2785641B1/en
Priority to PCT/EP2012/073405 priority patent/WO2013079396A1/en
Priority to CN201280059128.4A priority patent/CN104010970B/zh
Priority to US14/361,768 priority patent/US10493428B2/en
Publication of GB2497105A publication Critical patent/GB2497105A/en
Application granted granted Critical
Publication of GB2497105B publication Critical patent/GB2497105B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/283—Porous sorbents based on silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
    • B01J20/103—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate comprising silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B01J20/28007—Sorbent size or size distribution, e.g. particle size with size in the range 1-100 nanometers, e.g. nanosized particles, nanofibers, nanotubes, nanowires or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B01J20/2808—Pore diameter being less than 2 nm, i.e. micropores or nanopores
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/3078—Thermal treatment, e.g. calcining or pyrolizing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/3085—Chemical treatments not covered by groups B01J20/3007 - B01J20/3078
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3295—Coatings made of particles, nanoparticles, fibers, nanofibers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/113—Silicon oxides; Hydrates thereof
    • C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • C01B33/14—Colloidal silica, e.g. dispersions, gels, sols
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/113—Silicon oxides; Hydrates thereof
    • C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • C01B33/18—Preparation of finely divided silica neither in sol nor in gel form; After-treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/01—Particle morphology depicted by an image
    • C01P2004/03—Particle morphology depicted by an image obtained by SEM
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/30—Particle morphology extending in three dimensions
    • C01P2004/32—Spheres
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/50—Agglomerated particles
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/61—Micrometer sized, i.e. from 1-100 micrometer
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/62—Submicrometer sized, i.e. from 0.1-1 micrometer
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/64—Nanometer sized, i.e. from 1-100 nanometer
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/12—Surface area
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/16—Pore diameter

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Silicon Compounds (AREA)
GB1120665.3A 2011-12-01 2011-12-01 Process for the preparation of porous silica particles Active GB2497105B (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
GB1120665.3A GB2497105B (en) 2011-12-01 2011-12-01 Process for the preparation of porous silica particles
GB1404340.0A GB2508554B (en) 2011-12-01 2011-12-01 A stationary phase for liquid chromatography made from superficially porous particles
JP2014543843A JP6122438B2 (ja) 2011-12-01 2012-11-22 液体クロマトグラフィ用の多孔質粒子およびその調製方法
EP12794688.7A EP2785641B1 (en) 2011-12-01 2012-11-22 Porous particles for liquid chromatography and processes for the preparation thereof
PCT/EP2012/073405 WO2013079396A1 (en) 2011-12-01 2012-11-22 Porous particles for liquid chromatography and processes for the preparation thereof
CN201280059128.4A CN104010970B (zh) 2011-12-01 2012-11-22 用于液相色谱的多孔颗粒以及其制备方法
US14/361,768 US10493428B2 (en) 2011-12-01 2012-11-22 Porous particles for liquid chromatography and processes for the preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1120665.3A GB2497105B (en) 2011-12-01 2011-12-01 Process for the preparation of porous silica particles

Publications (3)

Publication Number Publication Date
GB201120665D0 GB201120665D0 (en) 2012-01-11
GB2497105A GB2497105A (en) 2013-06-05
GB2497105B true GB2497105B (en) 2014-07-23

Family

ID=45508991

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1120665.3A Active GB2497105B (en) 2011-12-01 2011-12-01 Process for the preparation of porous silica particles

Country Status (6)

Country Link
US (1) US10493428B2 (enExample)
EP (1) EP2785641B1 (enExample)
JP (1) JP6122438B2 (enExample)
CN (1) CN104010970B (enExample)
GB (1) GB2497105B (enExample)
WO (1) WO2013079396A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10434496B2 (en) 2016-03-29 2019-10-08 Agilent Technologies, Inc. Superficially porous particles with dual pore structure and methods for making the same
JP7290289B2 (ja) 2018-06-15 2023-06-13 国立大学法人東北大学 コアシェル型多孔質シリカ粒子の製造方法
US12286380B2 (en) 2019-03-12 2025-04-29 Basf Se Shaped artificial polymer articles
EP4121203A1 (en) * 2020-03-20 2023-01-25 Restek Corporation Spike particles, superficially porous spike particles, chromatographic separation devices, and processes for forming spike particles
CA3189382A1 (en) * 2020-09-11 2022-03-17 Jared M. CLINGER Affinity chromatography devices containing a heat treated fibrillated polymer membrane and manifolds containing the same
CN112852188B (zh) * 2020-12-28 2022-09-30 广东彤泰新材料科技有限公司 一种填料组合物
KR102635292B1 (ko) * 2021-08-26 2024-02-08 경희대학교 산학협력단 공극 구조 세라믹 나노 입자, 공극 구조 세라믹 나노 입자-탄소 동소체 복합체 및 이들의 제조방법
KR102693133B1 (ko) * 2021-09-01 2024-08-09 경희대학교 산학협력단 공극 구조의 세라믹 나노 입자-탄소 동소체 복합체를 이용한 리튬 이차전지의 음극 및 이의 제조방법
CN113929128B (zh) * 2021-10-27 2023-06-23 烟台佳隆纳米产业有限公司 CuO@SiO2纳米复合材料的制备方法
CN117753099B (zh) * 2023-11-10 2026-04-10 上海金鑫生物科技有限公司 功能性过滤测试滤芯及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090297853A1 (en) * 2006-02-13 2009-12-03 Advanced Materials Technology, Inc. Process for preparing substrates with porous surface
US20100051877A1 (en) * 2008-08-29 2010-03-04 Agilent Technologies, Inc. Superficially Porous Metal Oxide Particles, Methods For Making Them, and Separation Devices Using Them
EP2218500A2 (en) * 2009-02-17 2010-08-18 Agilent Technologies, Inc. Superficially porous particles and methods of making and using same
WO2012018598A1 (en) * 2010-07-26 2012-02-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3505785A (en) 1967-06-20 1970-04-14 Du Pont Superficially porous supports for chromatography
US20100116743A1 (en) 2007-06-04 2010-05-13 James Neil Pryor Silica particles and methods of making and using the same
JP2012509974A (ja) * 2008-11-26 2012-04-26 ユニバーシティ・カレッジ・コークーナショナル・ユニバーシティ・オブ・アイルランド，コーク シリカ微粒子を製造する方法
CN101961639A (zh) 2009-07-23 2011-02-02 中国科学院兰州化学物理研究所 二氧化硅核壳型液相色谱填料的制备方法
CN102070148B (zh) * 2009-11-23 2012-11-07 哈尔滨理工大学 单分散微米级球状介孔氧化硅mcm-41合成方法及应用

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090297853A1 (en) * 2006-02-13 2009-12-03 Advanced Materials Technology, Inc. Process for preparing substrates with porous surface
US20100051877A1 (en) * 2008-08-29 2010-03-04 Agilent Technologies, Inc. Superficially Porous Metal Oxide Particles, Methods For Making Them, and Separation Devices Using Them
EP2218500A2 (en) * 2009-02-17 2010-08-18 Agilent Technologies, Inc. Superficially porous particles and methods of making and using same
WO2012018598A1 (en) * 2010-07-26 2012-02-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
B. Lee et al. Synthesis of functionalized porous silicas via templating method as heavy metal ion adsorbents: the introduction of surface hydrophilicity onto the surface of adsorbents. Microporous and Mesoporous Materials 50, 77-90, 2001 *

Also Published As

Publication number Publication date
US20140329673A1 (en) 2014-11-06
JP6122438B2 (ja) 2017-04-26
US10493428B2 (en) 2019-12-03
CN104010970B (zh) 2016-12-21
CN104010970A (zh) 2014-08-27
EP2785641A1 (en) 2014-10-08
GB201120665D0 (en) 2012-01-11
WO2013079396A1 (en) 2013-06-06
GB2497105A (en) 2013-06-05
JP2015504410A (ja) 2015-02-12
EP2785641B1 (en) 2018-02-21

Similar Documents

Publication Publication Date Title
IL244704A (en) Microphoric zirconium silicate for the treatment of hypercalcemia
IL246265B (en) A method for the production of intermediates for the preparation of 5-fluoro-h1-pyrazolopyridines and such compounds
EP2552874A4 (en) PROCESS FOR PREPARING HEXAFLUOR-2 BUTENE
ZA201306583B (en) Modified silica particles
ZA201305972B (en) Method for the preparation of biphephos
EP2558432A4 (en) METHOD FOR THE PRODUCTION OF TETRAFLUOROLEFINES
PL2668163T3 (pl) Sposób wytwarzania 6-podstawionych 4-amino-3-chloro-5-fluoro-pikolinianów
SG11201400939YA (en) Process for the preparation of methoxymelonal
ZA201404440B (en) Process for the preparation of travoprost
GB201120665D0 (en) Porous particles for liquid chromatography and processes for the preparation thereof
PL2744772T3 (pl) Sposób wytwarzania sewofluranu
IL236450A0 (en) Process for the preparation of 5-fluoro-h1-pyrazoles
PL399418A1 (pl) Sposób wytwarzania 4-metoksydihydrochalkonu
PL399419A1 (pl) Sposób wytwarzania 4-metoksydihydrochalkonu
ZA201207397B (en) Process for the preparation of dexlansoprazole
EP2596007A4 (en) PROCESS FOR THE PREPARATION OF 17-DEOXY-CORTICOSTEROIDS
ZA201404385B (en) Process for the manufacture of ferrochrome
ZA201309713B (en) Process for the preparation of paliperidone
ZA201300546B (en) Process for the preparation of 3-haloalkylpyrazoles
ZA201303361B (en) Process for extrusing particles
GB201119690D0 (en) Process for the preparation of compounds
ZA201403104B (en) Process for the preparation of higher alcohols
PL393916A1 (pl) Sposób wytwarzania związków karbapenamowych
PT2702045T (pt) Método inovador para a preparação de etravirina
PT2390246T (pt) Processo para a preparação de aminaftona