GB2219999A - Substituted 5-pyrimidinecarboxamides and treatment of leukemia - Google Patents
Substituted 5-pyrimidinecarboxamides and treatment of leukemia Download PDFInfo
- Publication number
- GB2219999A GB2219999A GB8815055A GB8815055A GB2219999A GB 2219999 A GB2219999 A GB 2219999A GB 8815055 A GB8815055 A GB 8815055A GB 8815055 A GB8815055 A GB 8815055A GB 2219999 A GB2219999 A GB 2219999A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrimidinecarboxamide
- oxo
- hydroxy
- tetrahydro
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- LPSKSLRGCHZEDL-UHFFFAOYSA-N CC(CC1)CCC1C=C Chemical compound CC(CC1)CCC1C=C LPSKSLRGCHZEDL-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/557—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE8800818A BE1001263A4 (fr) | 1988-07-14 | 1988-07-14 | Procede en vue de provoquer la regression de la leucemie et l'inhibition de la croissance des tumeurs chez les mammiferes. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB8815055D0 GB8815055D0 (en) | 1988-08-03 |
| GB2219999A true GB2219999A (en) | 1989-12-28 |
Family
ID=3883532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8815055A Withdrawn GB2219999A (en) | 1988-07-14 | 1988-06-24 | Substituted 5-pyrimidinecarboxamides and treatment of leukemia |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE1001263A4 (zh) |
| FR (1) | FR2628869A1 (zh) |
| GB (1) | GB2219999A (zh) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2174391A (en) * | 1985-04-22 | 1986-11-05 | Uniroyal Chem Co Inc | 5-pyrimidinecarboxamides and treatment of leukemia and tumours therewith |
-
1988
- 1988-03-17 FR FR8803462A patent/FR2628869A1/fr active Pending
- 1988-06-24 GB GB8815055A patent/GB2219999A/en not_active Withdrawn
- 1988-07-14 BE BE8800818A patent/BE1001263A4/fr not_active IP Right Cessation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2174391A (en) * | 1985-04-22 | 1986-11-05 | Uniroyal Chem Co Inc | 5-pyrimidinecarboxamides and treatment of leukemia and tumours therewith |
Also Published As
| Publication number | Publication date |
|---|---|
| BE1001263A4 (fr) | 1989-09-05 |
| FR2628869A1 (zh) | 1989-09-22 |
| GB8815055D0 (en) | 1988-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |