GB2184726B - Azoniaspironortropanol esters, processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Azoniaspironortropanol esters, processes for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
GB2184726B
GB2184726B GB8630809A GB8630809A GB2184726B GB 2184726 B GB2184726 B GB 2184726B GB 8630809 A GB8630809 A GB 8630809A GB 8630809 A GB8630809 A GB 8630809A GB 2184726 B GB2184726 B GB 2184726B
Authority
GB
United Kingdom
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
azoniaspironortropanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8630809A
Other languages
English (en)
Other versions
GB2184726A (en
GB8630809D0 (en
Inventor
Wolf R Grimminger
Klaus Goerler
R Karl Peter Odenthal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madaus Holding GmbH
Original Assignee
Dr Madaus GmbH and Co
Madaus AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19853546218 external-priority patent/DE3546218A1/de
Priority claimed from DE19853546165 external-priority patent/DE3546165A1/de
Application filed by Dr Madaus GmbH and Co, Madaus AG filed Critical Dr Madaus GmbH and Co
Publication of GB8630809D0 publication Critical patent/GB8630809D0/en
Publication of GB2184726A publication Critical patent/GB2184726A/en
Application granted granted Critical
Publication of GB2184726B publication Critical patent/GB2184726B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB8630809A 1985-12-27 1986-12-23 Azoniaspironortropanol esters, processes for the preparation thereof and pharmaceutical compositions containing them Expired - Fee Related GB2184726B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853546218 DE3546218A1 (de) 1985-12-27 1985-12-27 Azoniaspironortropanolester, verfahren zu deren herstellung und pharmazeutisches mittel
DE19853546165 DE3546165A1 (de) 1985-12-27 1985-12-27 Verwendung von azoniaspironortropanolestern als asthmatherapeutikum und als broncholytikum

Publications (3)

Publication Number Publication Date
GB8630809D0 GB8630809D0 (en) 1987-02-04
GB2184726A GB2184726A (en) 1987-07-01
GB2184726B true GB2184726B (en) 1990-10-03

Family

ID=25839393

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8630809A Expired - Fee Related GB2184726B (en) 1985-12-27 1986-12-23 Azoniaspironortropanol esters, processes for the preparation thereof and pharmaceutical compositions containing them

Country Status (18)

Country Link
KR (1) KR930000113B1 (pt)
AT (1) AT397962B (pt)
AU (1) AU584266B2 (pt)
BE (1) BE906054A (pt)
CA (1) CA1304369C (pt)
CH (1) CH677793A5 (pt)
ES (1) ES2004177A6 (pt)
FI (1) FI865295A (pt)
FR (1) FR2598417B1 (pt)
GB (1) GB2184726B (pt)
HU (1) HU201930B (pt)
IT (1) IT1198263B (pt)
NL (1) NL193184C (pt)
PL (1) PL150843B1 (pt)
PT (1) PT84022B (pt)
SE (1) SE8605531L (pt)
SU (1) SU1711674A3 (pt)
YU (1) YU46038B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06003769A (es) * 2003-11-04 2006-07-03 Shire Lab Inc Liberacion sostenida de moleculas farmacologicamente activas cargadas positivamente a partir de una matriz que contiene polimeros con atomos de oxigeno polarizados.
WO2005046663A1 (en) * 2003-11-04 2005-05-26 Shire Laboratories, Inc. Compositions of quaternary ammonium containing bioavailability enhancers
CN101684117B (zh) * 2008-09-27 2013-06-12 宁波市医药技术研究有限公司 去甲托品醇的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1194422B (de) * 1963-03-05 1965-06-10 Robert Pfleger Chem Fab Dr Verfahren zur Herstellung von Azoniaspironortropanderivaten
US3480626A (en) * 1967-05-18 1969-11-25 Chem Fab Dr R Pfleger Certain azoniaspironortropine derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670258C3 (de) * 1967-08-04 1976-01-02 C.H. Boehringer Sohn, 6507 Ingelheim Verfahren zur Herstellung von N or scopolamin durch Entalkylierung tertiärer, cyclischer Amine
IT1140998B (it) * 1980-06-18 1986-10-10 Valeas Ind Chimica E Farmaceut Sali di endo-8-metil-8-sin-alchil-8-azoniabiciclo aperta par. quadrata 3.2.1. chiusa par. quadrata-ottan-3-alchilcarbossilati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1194422B (de) * 1963-03-05 1965-06-10 Robert Pfleger Chem Fab Dr Verfahren zur Herstellung von Azoniaspironortropanderivaten
GB1058542A (en) * 1963-03-05 1967-02-15 Robert Pfleger Chem Fab Dr Nortropane derivatives and the preparation thereof
US3480626A (en) * 1967-05-18 1969-11-25 Chem Fab Dr R Pfleger Certain azoniaspironortropine derivatives

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Arzneimittel-Forschung, 16(12) 1581- *
Arzneimittel-Forschung, 17(6) 719-26 *

Also Published As

Publication number Publication date
HU201930B (en) 1991-01-28
NL193184C (nl) 1999-02-02
SE8605531L (sv) 1987-06-28
AT397962B (de) 1994-08-25
CH677793A5 (pt) 1991-06-28
PT84022A (en) 1987-01-01
KR930000113B1 (ko) 1993-01-09
IT1198263B (it) 1988-12-21
KR870005998A (ko) 1987-07-08
YU46038B (sh) 1992-12-21
PT84022B (pt) 1989-07-31
HUT43060A (en) 1987-09-28
NL193184B (nl) 1998-10-01
ATA339286A (de) 1993-12-15
GB2184726A (en) 1987-07-01
AU6698586A (en) 1987-07-02
GB8630809D0 (en) 1987-02-04
FR2598417B1 (fr) 1993-10-29
IT8622877A0 (it) 1986-12-24
PL150843B1 (en) 1990-07-31
FI865295A0 (fi) 1986-12-23
FR2598417A1 (fr) 1987-11-13
ES2004177A6 (es) 1988-12-16
SE8605531D0 (sv) 1986-12-22
NL8603303A (nl) 1987-07-16
YU224986A (en) 1988-04-30
CA1304369C (en) 1992-06-30
FI865295A (fi) 1987-06-28
AU584266B2 (en) 1989-05-18
IT8622877A1 (it) 1988-06-24
BE906054A (fr) 1987-06-29
PL263216A1 (en) 1988-04-14
SU1711674A3 (ru) 1992-02-07

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Legal Events

Date Code Title Description
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20011223