GB2181349A - Skin care composition containing polyunsaturated fatty acids - Google Patents

Skin care composition containing polyunsaturated fatty acids Download PDF

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Publication number
GB2181349A
GB2181349A GB08624033A GB8624033A GB2181349A GB 2181349 A GB2181349 A GB 2181349A GB 08624033 A GB08624033 A GB 08624033A GB 8624033 A GB8624033 A GB 8624033A GB 2181349 A GB2181349 A GB 2181349A
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Prior art keywords
oil
composition
component
fatty acids
mixture
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Granted
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GB08624033A
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GB8624033D0 (en
GB2181349B (en
Inventor
Elisabeth Anne Papaconstantin
Claude Bonne
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Parfums Rochas SAS
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Parfums Rochas SAS
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Publication of GB8624033D0 publication Critical patent/GB8624033D0/en
Publication of GB2181349A publication Critical patent/GB2181349A/en
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Publication of GB2181349B publication Critical patent/GB2181349B/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

A cosmetic or dermatological composition for skin care contains as active ingredient a mixture comprising: A) One or more triglycerides of polyunsaturated essential fatty acids containing from 18 to 22 carbon atoms; and B) One or more polyunsaturated essential fatty acids containing from 18 to 22 carbon atoms in free form or in the form of alkali metal or ammonium salts. A preferred active ingredient is a partially saponified polyunsaturated oil (e.g. sunflower oil, corn oil, borage oil, blade-currant pip oil or evening primrose oil).

Description

SPECIFICATION Skin Care Composition The present invention relates to a new cosmetic or dermatological composition for skin care. The composition contains, and is preferably rich in, polyunsaturated essential fatty acid present both in the form of triglyceride and in the free or salified form.
The essential fatty acids are nutritive substances which are indispensable to man but which he cannot himself synthesize. They are a group of natural fatty acids with 18, 20 or 22 carbon atoms, containing several unsaturated double bonds.
The lack of essential fatty acids, which increases with age, leads to numerous problems of the organism and particularly to skin problems. These latter are betrayed by a dried-up appearance and a loss of suppleness and elasticity of the skin.
In fact, the essential fatty acids take part in the role of barrier conferred on the epidermis which controls the loss of water from the skin. They are thus indispensable to the integrity of the cellular membranes.
Applying essential fatty acids by the topical route thus enables the hydration of the skin to be preserved.
In cosmetic compositions, these essential fatty acids are most often brought in through the intermediary of a vegetable oil which contains them in a more or less large quantity in the form of triglycerides.
It has now been found that the essential fatty acids, free or in the salified form, mix with the membrane phospho-lipids of the skin.
On the other hand, it seems that bringing in the essential fatty acids by the topical route with the help of the oils does not always enable a sufficient mixing of the said acids with the membrane phospho-lipids.
It seems that this mixing is influenced by the lipase activity of the skin. This varies from one individual to another and depends on numerous factors such as the general state, the age, and the cutaneous pH.
There has now been produced therefore cosmetic or dermatological compositions which improve the bio-availability at the cellular level of the essential fatty acids which they contain.
Accordingly, the invention provides a cosmetic or dermatological composition for skin care containing as active ingredient á mixture comprising: A) One or more triglycerides of polyunsaturated essential fatty acids containing from 18 to 22 carbon atoms; and B) One or more polyunsaturated essential fatty acids containing from 18 to 22 carbon atoms in free form or in the form of alkali metal or ammonium salts.
The invention provides also a process for preparing the composition, which process comprises admixing the ingredients.
The invention also provides a process for preparing the composition in which the mixture has been obtained by a process comprising the partial saponification of the same substance as component A, so that some of the substance is left to form component A and some is saponified to form component B.
The invention also provides the composition for use in a method for the dermatological treatment of the skin.
The invention provides also a method of cosmetically treating skin, which method comprises applying thereto a cosmetic amount of the composition.
The present composition may contain the present active ingredient for instance as the principal active ingredient (i.e. the active ingredient present in the highest amount by weight).
In the present compositions, component B reinforces the effectiveness of component A. The compositions contain the necessary essential fatty acids while facilitating their absorption in the membrane phospho-lipids in sufficient quantity for an improvement of the cutaneous appearance to be observed.
In component A, the triglycerides of the essential fatty acids can be the usual triglycerides of synthesis.
These triglycerides can be brought in by the intermediary of one or more sources containing them in a natural state. Such sources are essentially vegetable oils. There can be mentioned, for example, wheat germ oil, olive oil, corn oil, sunflower oil, sweet almond oil, evening prim rise oil, borage oil, or black-current pip oil. All these oils contain very variable proportions of one or more essential fatty acids.
Component B can be particularly one or more polyunsaturated essential fatty acids containing from 18 to 22 carbon atoms in free form or in the form of alkali metal or ammonium salts arising wholly or partly from saponification of the same substance as component A. In the latter case, the composition contains a particular substance as component A and the same substance saponified as, or as part of, component B.
The saponification of the triglycerides of component A can be effected by very common methods, particularly by an alkali metal hydroxide (usually sodium or potassium hydroxide).
The saponification can be carried out in the presence of an antioxidant, in view of the very ready oxidation of polyunsaturated fatty acids.
When component B comprises one or more polyunsaturated fatty acids in the form of an alkali metal salt, it is preferred to be a sodium or potassium salt.
In order that the present invention should be as effective as possible at the cell level, components A and B should be present respectively in proportions ensuring the mixing of 5 to 10 % of the essential fatty acids present in the free or salified form in the membrane phospho-lipids. Such a result can be obtained when the present compositions contain from 1 to 20 % by weight of component A and 0.5 to 5 % by weight of component B.
There are two outstandingly important families of polyunsaturated acids, the linolenic family and the linoleic family.
The most abundant essential fatty acids at the cutaneous level have as a precursor, linoleic acid metabolized according to the following scheme: C18:2 C18:3 C20:3 C20:4 linoleic y-linolenic dihomo arachidonic acid acid y-linolenic acid acid All these acids are therefore particularly indispensable to normal growth and the physiological activity of the tissues.
Hence, component A is particularly one or more triglycerides of the following polyunsaturated fatty acids: - linoleic acid : C18 : 2,n-6 -a-linolenicacid : C18 3,n-3 -y-linolenicacid : C18 3,n-6 - dihomo y-linolenic acid : C20 : 3,n-6 - arachidonic acid : C20 : 4,n-6 Oils rich in essential fatty acids in the form oftriglycerides mentioned above are sunflower oil (57% linoleic acid), corn oil (40% linoleic acid), evening primrose oil (71% linoleic acid, 9% y-linolenic acid), borage oil, and black-currant pip oil.
In man, the conversion of linoleic acid into y-linolenic acid is the limiting stage, and can be made more inoperative by numerous external influences. In particular, this stage is deficient during ageing. Among the essential fatty acids mentioned above linolenic acid is therefore particularly interesting.
The present mixture therefore comprises particularly: A) An oil obtained starting from a source containing, preferably rich in, y-linolenic acid; and B) A mixture containing, preferably rich in, alkali metal or ammonium salt of y-linolenic acid.
The present mixture comprises more particularly: A) An oil obtained starting from a source containing, preferably rich in, y-linolenic acid; and B) A mixture containing, preferably rich in, alkali metal or ammonium salt of y-linolenic acid arising from saponification of the same oil as component A.
Evening primrose oil extracted from the seeds of Oenothera biennis or Oenothera lamarkiana plants, blackcurrant seed oil and borage oil are the three principal vegetable oils rich in y-linolenic acid.
Among the oils containing y-linolenic acid which can be used in the compositions of the invention, there can also be mentioned the oil obtained by extraction from siphomycetes mushrooms, from spirulines, from maple seeds or from hops.
Naturally, there can be used any other oil extracted from a natural source of y-linolenic acid.
The present mixture can be particularly: A) Evening primrose oil or borage oil; and B) A mixture containing, preferably rich in, alkali metal salt of y-linolenic acid.
The composition quite particularly can contain as active ingredient a mixture comprising: A) Evening primrose oil; and B) A mixture containing, preferably rich in, alkali metal salt of y-linolenic acid arising from saponification of the same oil as component A.
The present compositions can contain, if desired, any substance known as having beneficial properties on the skin, such as callogen, elastin, hyaluronic acid, sterols, biologically active extracts of animal or vegetable origin, moisteners such as urea, pyrrolidone carboxylic acid and its salts, vitamin extracts, perfumes, preservatives, or colouring materials.
They can also contain small quantities of solar radiation filters or screens. These might be, for example, filters of UVA and UVB radiations, such as, for example, hydroxy-2-methoxy-4-benzophene, or dimethoxy 3,4-phenyl glyoxylic acid in the form of the sodium salt. The composition can also contain products which block the formation of free radicals and singlet oxygen. These products enable solar radiations other than UV to be stopped. These products are, for example, terpenes, the lipo-soluble extract of carrot, a-tocopherol or other quenchers.
The compositions also advantageously contain anti-oxidants such for example as y-oryzanol.
All the substances mentioned above enable the skin to be protected from all harmful solar radiation and a very effective photo-protective action to be obtained. a The compositions can be presented in any of the forms used in cosmetics, such as cream or gel in pots or tubes, or milk or lotion, in a glass or plastic bottle, possibly in a measuring flask or in phials.
The invention accordingly provides the cosmetic or dermatological composition in the form of creams, gels, milk, dermatological bars, or lotion for the skin. The composition is preferably adapted, particularly by reason of excipients therein, for application to the face and neck.
In each form, appropriate excipients can be employed. These excipients should have all the qualities usually demanded. They should be endowed with a great affinity for the skin, be perfectly well tolerated and stable, and possess a suitable consistency enabling easy and pleasant use.
As examples of excipients which can be used, there can be mentioned glycerol stearate, propylene glycol, palmitate and stearate derivatives, lanoline, glycerin, cetyl alcohol, polyol, animal and mineral oils, waxes, moisteners, thickeners, stabilisers, and emulsifiers as currently used.
The different cosmetic forms mentioned above can be obtained by methods usual in this field.
A previously saponified oil can be incorporated in the mixture containing all the ingredients necessary for the preparation of the composition.
It is also possible to saponify part of the oil present in the mixture at the same time as the desired composition is prepared, by adding sodium hydroxide or potassium hydroxide in sufficient quantity.
The invention is illustrated by the following Examples, in which amounts are in grams.
1. Example of Cream (Oil in Water Emulsion) Glycerol stearate 5 Wheat germ oil 2 Evening primrose oil from 5to 15 Jojoba oil 2 y-tocopherol 0.05 Propyleneglycol 2 Evening primrose soap from 1 to 5 Carboxyvinyl polymer 0.5 Triethanolamine 0.5 Aromatic composition q.s.
Preservatives q.s.
Water q.s. for 100 2. Example of Milk (Oil in Water Emulsion) polyethoxyetherphosphate of oleic alcohol 2 Cetyl alcohol 0.5 Anhydrous lanoline 0.5 . Silicone fluid 1 Evening primrose oil 2 Stearic acid, triple pressed 3 Triethanolamine 0.5 Propyleneglycol 5 B.H.T. (butylated hydroxytoluene) 5 Magnesium aluminium silicate 0.5 Evening primrose soap from 0.5to 1.5 Aromatic composition q.s.
Preservatives q.s.
Water q.s.
3. Example of Moisturizing Cream (Water in Oil Emulsion) Ceresin was, 65"C 3 Paraffin 6080 C 2 Evening primrose oil 10 Perhydrosqualene 5 y-orizanol 0.1 Sorbitol monoisostearate 2
Sodium lactate (60% aq. sol.) Sodium pyrolidone carboxylate, (50% aq. sol.)
Lactic acid, q.s. for pH 7 Evening primrose soap 1 to3 Aromatic composition q.s.
Hydrolysat of silk powder 0.3 . Water q.s. for 100 4. Face Cream Borage oil or evening primrose oil 1.5 to 5 - Reconstituted sebum 1 to 3 Borage soap or evening primrose soap 0.5 to 1.5 Silicone oil 1 to 3 Jojoba oil 3 to 5 Stearin 0.5 to 1 Methyl glucoside sesquistearate 3 P.O.E. (polyoxyethylene) 20 methyl glucoside sesquistearate 2 Urea 0.3 to 0.5 Hafnia extract 0.05 Free radical collectors 0.05 Biological derivatives of vegetable oranimal origin 0.1 to 1 Preservative q.s.
Aromatic Composition q.s.
Water q.s. for 100

Claims (16)

1. Cosmetic or dermatological composition for skin care containing as active ingredient a mixture comprising: A) One or more triglycerides of polyunsaturated essential fatty acids containing from 18 to 22 carbon atoms; and B) One or more polyunsaturated essential fatty acids containing from 18 to 22 carbon atoms in free form or in the form of alkali metal or ammonium salts.
2. Composition according to claim 1 which' contains 1 to 20% by weight of component A and 0.5 to 5 % by weight of component B.
3. Composition according to claim 1 or 2 wherein component A is one or more triglycerides of the following polyunsaturated fatty acids: - linoleic acid : C18 2.n-6 -a-Iinolenicacid : C18 3,n-3 -y-Iinolenicacid : C18 3,n-6 -dihomoy-linolenicacid : C20 3,n-6 - arachidonic acid : C20 : 4,n-6
4. Composition according to any one of the preceding claims wherein component B is one or more polyunsaturated essentially fatty acids containing from 18 to 22 carbon atoms in.free form or in the form of alkali metal or ammonium salts arising wholly or partly from saponification of the same substance as component A.
5. Composition according to any one of claims 1-3 wherein the mixture comprises: A) An oil obtained starting from a source rich in y-linolenic acid; and B) A mixture rich in alkali metal or ammonium salt of y-linolenic acid.
6. Composition according to any one of the preceding claims wherein the mixture comprises: A) An oil obtained starting from a source rich in y-linolenic acid; and B) A mixture rich in alkali metal or ammonium salt of y-linolenic acid arising from saponification of the same oil as component A.
7. Composition according to any one of claims 1-6 wherein the mixture comprises: A) Evening primrose oil or borage oil; and B) A mixture rich in alkali metal salt of y-linolenic acid.
8. Composition according to any one of the preceding claims wherein the mixture comprises: A) Evening primrose oil; and B) A mixture rich in alkali metal salt of y-linolenic acid arising from saponification of the same oil as component A.
9. Composition according to claim 1 substantially as described herein.
10. Cosmetic or dermatological composition substantially as described herein in any one of the Examples.
11. A process for preparing a composition claimed in any one of the preceding claims, which process comprises admixing the ingredients.
12. A process for preparing a composition claimed in any one of claims 1-10 wherein the mixture has been obtained by a process comprising the partial saponification of the same substance as component A.
13. A process for preparing a composition claimed in any one of claims 1-10, which process is performed substantially as described herein.
14. Composition claimed in any one of claims 1-10 prepared by a process claimed in any one of claims 11-13.
15. Composition for use in a method for the dermatological treatment of the skin, which composition is as claimed in any one of claims 1-10 and 14.
16. Method of cosmetically treating skin, which method comprises apolying thereto a cosmetic amount of a composition claimed in any of claims 1-10 and 14.
GB8624033A 1985-10-07 1986-10-07 Skin care composition Expired GB2181349B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8514807A FR2588187B1 (en) 1985-10-07 1985-10-07 NEW COSMETIC OR DERMATOLOGICAL COMPOSITIONS RICH IN ESSENTIAL FATTY ACIDS PRESENT BOTH IN THE FORM OF TRIGLYCERIDES AND IN THE FREE OR SALIFIED FORM

Publications (3)

Publication Number Publication Date
GB8624033D0 GB8624033D0 (en) 1986-11-12
GB2181349A true GB2181349A (en) 1987-04-23
GB2181349B GB2181349B (en) 1989-12-13

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Family Applications (1)

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GB8624033A Expired GB2181349B (en) 1985-10-07 1986-10-07 Skin care composition

Country Status (8)

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BE (1) BE905558A (en)
CH (1) CH669727A5 (en)
DE (1) DE3634152C2 (en)
FR (1) FR2588187B1 (en)
GB (1) GB2181349B (en)
IT (1) IT1214723B (en)
OA (1) OA08423A (en)
ZA (1) ZA867647B (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0331489A3 (en) * 1988-03-03 1990-03-28 Parke Davis Pty. Ltd. Acne treatment
EP0346451A4 (en) * 1987-12-31 1991-04-10 Research Foundation For Mental Hygiene, Inc. Antiviral and antibacterial activity of fatty acids and monoglycerides
EP0467218A2 (en) * 1990-07-17 1992-01-22 Beiersdorf Aktiengesellschaft Combinations of active agents for skin care
WO1992010164A1 (en) * 1990-12-05 1992-06-25 Ulrich Heverhagen Agent for reducing the growth of, or removing, human body hair
EP0520624A1 (en) * 1991-06-03 1992-12-30 Scotia Holdings Plc Nutritional, pharmaceutical and cosmetic compositions containing di-linoleoyl-mono-gamma-linolenyl-glycerol
FR2681783A1 (en) * 1991-09-27 1993-04-02 Bourjois Sa Mixture of vegetable oils which is rich in essential fatty acids and its use in cosmetic compositions
EP0611569A2 (en) * 1993-01-27 1994-08-24 Scotia Holdings Plc Triglycerides
EP0640581A1 (en) * 1993-08-25 1995-03-01 Biox Corporation Endermic nutrient material and cosmetic composition containing the same
US5434182A (en) * 1987-12-31 1995-07-18 Isaacs; Charles E. Antibacterial fatty acid compositions
WO1997035570A1 (en) * 1996-03-26 1997-10-02 Beiersdorf Ag Use of unsaturated monocarboxylic acids against superinfections
EP0826366A2 (en) * 1996-08-30 1998-03-04 Unilever Plc Cosmetic compositions containing hydroxy acid or retinoid
WO2002009524A1 (en) * 2000-07-27 2002-02-07 Puritas Ab A new antibacterial composition comprising as an active ingredient saponificated vegetable oil
FR2903014A1 (en) * 2006-06-30 2008-01-04 Occitane L COSMETIC COMPOSITION BASED ON POLYUNSATURATED FATTY ACIDS AND USES THEREOF
WO2016000863A1 (en) 2014-06-30 2016-01-07 Unilever Plc Nitrogen containing borane stabilized skin care compositions

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Publication number Priority date Publication date Assignee Title
FR2604624B1 (en) * 1986-10-07 1991-04-26 Rochas Parfums NEW COSMETIC OR DERMATOLOGICAL COMPOSITIONS RICH IN ESSENTIAL FATTY ACIDS PRESENT BOTH IN THE FORM OF TRIGLYCERIDES AND IN THE FREE OR SALIFIED FORM
FR2617161B1 (en) * 1987-06-29 1989-10-27 Azar Robert NOVEL UNSATURATED FATTY ACID GLYCERIDES AND PROCESS FOR OBTAINING SAME
DE4435290A1 (en) * 1994-10-01 1996-04-04 Beiersdorf Ag Dermatological preparations containing fatty acids and fatty acid glycerides against superinfections
FR2780976B1 (en) * 1998-07-08 2001-06-29 Jean Noel Thorel NOVEL SURFACTANTS, AND THEIR USE IN COSMETICS AND DERMO-PHARMACY
DE10311852A1 (en) † 2003-03-17 2004-10-14 Henkel Kgaa Textile treatment agents
DE10326010A1 (en) * 2003-06-10 2005-01-05 Henkel Kgaa Preparation for the skin
DE10347487A1 (en) * 2003-09-30 2005-04-21 Kneipp Werke Kneipp Mittel Zen Cosmetic or dermatological composition for topical use

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GB1082624A (en) * 1965-02-26 1967-09-06 Calmic Ltd Improvements in or relating to therapeutically active compounds
FR2197605A1 (en) * 1972-09-06 1974-03-29 Williams John Foodstuff or skin nutrient to combat cholesterolaemia - contains arachidonic acid or gamma linolenic acid or esters and salts thereof
FR2513517A1 (en) * 1981-09-30 1983-04-01 Chevalier Jacques Gastro:resistant compsns. for treating hyperlipidaemia - contg. oil rich in polyunsaturated cpds. and vitamin-B cpds.
DE3368377D1 (en) * 1982-04-16 1987-01-29 Nestle Sa Lipid composition for oral, enteral or parenteral feeding
LU85130A1 (en) * 1983-12-12 1985-09-12 Oreal AQUEOUS COSMETIC OR ANHYDROUS COMPOSITION CONTAINING A FATTY PHASE BASED ON SHEA OIL
FR2557452B1 (en) * 1983-12-28 1986-08-14 Roussel Uclaf NOVEL COMPOSITIONS FOR SKIN CARE CONTAINING PRIMER OIL AND RATE TISSUE TRAITS

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0346451A4 (en) * 1987-12-31 1991-04-10 Research Foundation For Mental Hygiene, Inc. Antiviral and antibacterial activity of fatty acids and monoglycerides
US5434182A (en) * 1987-12-31 1995-07-18 Isaacs; Charles E. Antibacterial fatty acid compositions
EP0331489A3 (en) * 1988-03-03 1990-03-28 Parke Davis Pty. Ltd. Acne treatment
EP0467218A3 (en) * 1990-07-17 1993-03-03 Beiersdorf Aktiengesellschaft Combinations of active agents for skin care
EP0467218A2 (en) * 1990-07-17 1992-01-22 Beiersdorf Aktiengesellschaft Combinations of active agents for skin care
WO1992010164A1 (en) * 1990-12-05 1992-06-25 Ulrich Heverhagen Agent for reducing the growth of, or removing, human body hair
US5614208A (en) * 1991-06-03 1997-03-25 Efamol Holdings Plc Methods of treatment using di-linoleoyl-mono-gamma-linolenyl glycerol
US5328691A (en) * 1991-06-03 1994-07-12 Efamol Holdings Plc Fatty acid compositions
EP0520624A1 (en) * 1991-06-03 1992-12-30 Scotia Holdings Plc Nutritional, pharmaceutical and cosmetic compositions containing di-linoleoyl-mono-gamma-linolenyl-glycerol
US5620701A (en) * 1991-06-03 1997-04-15 Scotia Holdings Plc Methods of treatment using di-linoleoyl-mono-gamma-linolenyl glycerol
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Also Published As

Publication number Publication date
IT1214723B (en) 1990-01-18
GB8624033D0 (en) 1986-11-12
OA08423A (en) 1988-06-30
FR2588187A1 (en) 1987-04-10
ZA867647B (en) 1987-12-30
IT8648518A0 (en) 1986-10-06
FR2588187B1 (en) 1989-04-14
CH669727A5 (en) 1989-04-14
BE905558A (en) 1987-04-06
GB2181349B (en) 1989-12-13
DE3634152A1 (en) 1987-04-09
DE3634152C2 (en) 1996-06-20

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