GB2153358B - 1a,25-dihydroxy-22z-dehydrovitamin d2 compound - Google Patents

1a,25-dihydroxy-22z-dehydrovitamin d2 compound

Info

Publication number
GB2153358B
GB2153358B GB08502161A GB8502161A GB2153358B GB 2153358 B GB2153358 B GB 2153358B GB 08502161 A GB08502161 A GB 08502161A GB 8502161 A GB8502161 A GB 8502161A GB 2153358 B GB2153358 B GB 2153358B
Authority
GB
United Kingdom
Prior art keywords
dehydrovitamin
dihydroxy
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08502161A
Other languages
English (en)
Other versions
GB8502161D0 (en
GB2153358A (en
Inventor
Hector F Deluca
Heinrich K Schnoes
Rafal R Sicinski
Yoko Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of GB8502161D0 publication Critical patent/GB8502161D0/en
Publication of GB2153358A publication Critical patent/GB2153358A/en
Application granted granted Critical
Publication of GB2153358B publication Critical patent/GB2153358B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
GB08502161A 1984-01-30 1985-01-29 1a,25-dihydroxy-22z-dehydrovitamin d2 compound Expired GB2153358B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57511484A 1984-01-30 1984-01-30

Publications (3)

Publication Number Publication Date
GB8502161D0 GB8502161D0 (en) 1985-02-27
GB2153358A GB2153358A (en) 1985-08-21
GB2153358B true GB2153358B (en) 1987-07-22

Family

ID=24299012

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08502161A Expired GB2153358B (en) 1984-01-30 1985-01-29 1a,25-dihydroxy-22z-dehydrovitamin d2 compound

Country Status (11)

Country Link
JP (1) JPS61501147A (enrdf_load_stackoverflow)
AU (1) AU587174B2 (enrdf_load_stackoverflow)
BE (1) BE901601A (enrdf_load_stackoverflow)
CH (1) CH665835A5 (enrdf_load_stackoverflow)
DE (2) DE3590021T (enrdf_load_stackoverflow)
DK (1) DK437685D0 (enrdf_load_stackoverflow)
FR (1) FR2558828B1 (enrdf_load_stackoverflow)
GB (1) GB2153358B (enrdf_load_stackoverflow)
IE (1) IE57936B1 (enrdf_load_stackoverflow)
NL (1) NL8520009A (enrdf_load_stackoverflow)
WO (1) WO1985003300A1 (enrdf_load_stackoverflow)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3590020T1 (de) * 1984-01-30 1986-01-23 Wisconsin Alumni Research Foundation, Madison, Wis. In der Seitenkette ungesättigte 1-Hydroxyvitamin D-Verbindungen
DE3590080T (de) * 1984-03-05 1986-02-20 Wisconsin Alumni Research Foundation, Madison, Wis. 1α-Hydroxyvitamin D↓2↓-Analogverbindungen und Verfahren zu deren Herstellung
EP0211863B1 (en) * 1985-01-17 1992-12-30 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
US5246925A (en) * 1989-03-09 1993-09-21 Wisconsin Alumni Research Foundation 19-nor-vitamin D compounds for use in treating hyperparathyroidism
NZ232734A (en) * 1989-03-09 1991-11-26 Wisconsin Alumni Res Found 19-nor vitamin d derivatives and pharmaceutical compositions
CA1333616C (en) * 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
CA1138859A (en) * 1979-02-15 1983-01-04 Teijin Limited 25-hydroxy-24-oxocholestane derivatives and preparation thereof
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same

Also Published As

Publication number Publication date
IE850213L (en) 1985-07-30
AU587174B2 (en) 1989-08-10
WO1985003300A1 (en) 1985-08-01
FR2558828A1 (fr) 1985-08-02
JPS61501147A (ja) 1986-06-12
GB8502161D0 (en) 1985-02-27
DK437685A (da) 1985-09-27
JPH0455425B2 (enrdf_load_stackoverflow) 1992-09-03
IE57936B1 (en) 1993-05-19
DE3590021C2 (de) 1992-09-10
GB2153358A (en) 1985-08-21
CH665835A5 (de) 1988-06-15
DK437685D0 (da) 1985-09-27
AU3837285A (en) 1985-08-09
NL8520009A (nl) 1985-12-02
BE901601A (fr) 1985-05-17
FR2558828B1 (fr) 1987-11-20
DE3590021T (de) 1986-01-23

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19980129