IE850213L - Dihydroxy dehydrovitamin d compound - Google Patents

Dihydroxy dehydrovitamin d compound

Info

Publication number
IE850213L
IE850213L IE850213A IE21385A IE850213L IE 850213 L IE850213 L IE 850213L IE 850213 A IE850213 A IE 850213A IE 21385 A IE21385 A IE 21385A IE 850213 L IE850213 L IE 850213L
Authority
IE
Ireland
Prior art keywords
compound
dehydrovitamin
dihydroxy
vitamin
metabolites
Prior art date
Application number
IE850213A
Other versions
IE57936B1 (en
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IE850213L publication Critical patent/IE850213L/en
Publication of IE57936B1 publication Critical patent/IE57936B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Novel vitamin D derivative, 1$g(a),25-dihydroxy-22Z-dehydrovitamin D2?. The compound is characterized by unexpectedly high ability to raise serum calcium levels. The compound could therefore, find ready application as a substitute for vitamin D or its metabolites in the treatment of metabolic bone diseases or in other of their known applications. [WO8503300A1]
IE213/85A 1984-01-30 1985-01-29 1alpha,25-dihydroxy-22z-dehydrovitamin d compound IE57936B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57511484A 1984-01-30 1984-01-30

Publications (2)

Publication Number Publication Date
IE850213L true IE850213L (en) 1985-07-30
IE57936B1 IE57936B1 (en) 1993-05-19

Family

ID=24299012

Family Applications (1)

Application Number Title Priority Date Filing Date
IE213/85A IE57936B1 (en) 1984-01-30 1985-01-29 1alpha,25-dihydroxy-22z-dehydrovitamin d compound

Country Status (11)

Country Link
JP (1) JPS61501147A (en)
AU (1) AU587174B2 (en)
BE (1) BE901601A (en)
CH (1) CH665835A5 (en)
DE (2) DE3590021T (en)
DK (1) DK437685A (en)
FR (1) FR2558828B1 (en)
GB (1) GB2153358B (en)
IE (1) IE57936B1 (en)
NL (1) NL8520009A (en)
WO (1) WO1985003300A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3590020C2 (en) * 1984-01-30 1995-03-09 Wisconsin Alumni Res Found 1-Hydroxy-vitamin-D compounds which are unsaturated in the side chain
DE3590080C2 (en) * 1984-03-05 1992-08-06 Wisconsin Alumni Research Foundation, Madison, Wis., Us
WO1986004333A1 (en) * 1985-01-17 1986-07-31 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
CA1333616C (en) * 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
US5246925A (en) * 1989-03-09 1993-09-21 Wisconsin Alumni Research Foundation 19-nor-vitamin D compounds for use in treating hyperparathyroidism
NZ232734A (en) * 1989-03-09 1991-11-26 Wisconsin Alumni Res Found 19-nor vitamin d derivatives and pharmaceutical compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
DK162648C (en) * 1979-02-15 1992-04-13 Teijin Ltd 3BETA, 25-DIHYDROXY-24-OXOCHOLEST-5-ONE DERIVATIVES AND PROCEDURES FOR PREPARING IT
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same

Also Published As

Publication number Publication date
AU587174B2 (en) 1989-08-10
DE3590021C2 (en) 1992-09-10
GB8502161D0 (en) 1985-02-27
JPS61501147A (en) 1986-06-12
BE901601A (en) 1985-05-17
NL8520009A (en) 1985-12-02
FR2558828A1 (en) 1985-08-02
JPH0455425B2 (en) 1992-09-03
IE57936B1 (en) 1993-05-19
FR2558828B1 (en) 1987-11-20
DE3590021T (en) 1986-01-23
DK437685D0 (en) 1985-09-27
GB2153358A (en) 1985-08-21
CH665835A5 (en) 1988-06-15
GB2153358B (en) 1987-07-22
AU3837285A (en) 1985-08-09
DK437685A (en) 1985-09-27
WO1985003300A1 (en) 1985-08-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed