GB2140008B - Niflumic acid morpholinoethyl ester diniflumate - Google Patents

Niflumic acid morpholinoethyl ester diniflumate

Info

Publication number
GB2140008B
GB2140008B GB08409104A GB8409104A GB2140008B GB 2140008 B GB2140008 B GB 2140008B GB 08409104 A GB08409104 A GB 08409104A GB 8409104 A GB8409104 A GB 8409104A GB 2140008 B GB2140008 B GB 2140008B
Authority
GB
United Kingdom
Prior art keywords
niflumic acid
morpholinoethyl ester
diniflumate
acid morpholinoethyl
ester diniflumate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08409104A
Other languages
English (en)
Other versions
GB8409104D0 (en
GB2140008A (en
Inventor
Nicole Bru-Magniez
Jean-Marie Teulon
Romano Deghenghi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexachimie SA
Original Assignee
Hexachimie SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexachimie SA filed Critical Hexachimie SA
Publication of GB8409104D0 publication Critical patent/GB8409104D0/en
Publication of GB2140008A publication Critical patent/GB2140008A/en
Application granted granted Critical
Publication of GB2140008B publication Critical patent/GB2140008B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
GB08409104A 1983-04-21 1984-04-09 Niflumic acid morpholinoethyl ester diniflumate Expired GB2140008B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8306579A FR2544718B1 (fr) 1983-04-21 1983-04-21 Diniflumate d'ester morpholinoethylique d'acide niflumique, preparation, utilisation en therapeutique comme analgesique et anti-inflammatoire

Publications (3)

Publication Number Publication Date
GB8409104D0 GB8409104D0 (en) 1984-05-16
GB2140008A GB2140008A (en) 1984-11-21
GB2140008B true GB2140008B (en) 1986-11-12

Family

ID=9288097

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08409104A Expired GB2140008B (en) 1983-04-21 1984-04-09 Niflumic acid morpholinoethyl ester diniflumate

Country Status (26)

Country Link
US (1) US4595686A (enExample)
EP (1) EP0129449B1 (enExample)
JP (1) JPS59199676A (enExample)
KR (1) KR880001477B1 (enExample)
AR (1) AR240314A1 (enExample)
AT (1) ATE33639T1 (enExample)
AU (1) AU561210B2 (enExample)
CA (1) CA1218064A (enExample)
DE (1) DE3470534D1 (enExample)
DK (1) DK157858C (enExample)
EG (1) EG17886A (enExample)
ES (1) ES8502111A1 (enExample)
FR (1) FR2544718B1 (enExample)
GB (1) GB2140008B (enExample)
GR (1) GR81476B (enExample)
HU (1) HU194877B (enExample)
IE (1) IE57219B1 (enExample)
IL (1) IL71525A (enExample)
MA (1) MA20097A1 (enExample)
MY (1) MY100483A (enExample)
NZ (1) NZ207913A (enExample)
PH (1) PH18986A (enExample)
PT (1) PT78432B (enExample)
SG (1) SG107587G (enExample)
YU (1) YU65784A (enExample)
ZA (1) ZA842672B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192724A (en) * 1992-03-17 1993-03-09 Phillips Petroleum Company Reactivation of spent cracking catalysts
GB0006897D0 (en) * 2000-03-23 2000-05-10 Smithkline Beecham Plc Medicaments
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質(rap)結合体の投与による肝障害の処置
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US27822A (en) * 1860-04-10 Isaac mott
GB1146459A (en) * 1966-11-14 1969-03-26 American Cyanamid Co Nicotinic acid derivatives and method of preparing the same
GB1187259A (en) * 1967-10-23 1970-04-08 Hexachimie New Aminoalkyl Esters of 2-Anilino-Nicotinic Acids and process for their manufacture
USRE27822E (en) 1971-07-06 1973-11-27 Substituted phenoxy-z-hydroxy- j-isopropylamino-propanes
DE2601548C2 (de) * 1976-01-16 1984-01-26 Hoechst Ag, 6230 Frankfurt 2-[4-(2'-Chlor-4'-bromphenoxy)-phenoxy]-propionsäure und Derivate sowie diese enthaltende herbizide Mittel
AR208619A1 (es) * 1976-09-02 1977-02-15 Bago Sa Labor Un procedimiento para la obtencion de 2(3'-trifluormetilanilino)nicotinato de 5-hidroxi-6-metil-3,4-piridina dimetano
US4386090A (en) * 1980-12-22 1983-05-31 Delalande S.A. Nitrogen containing 2,3-dihydro naphthalenes, compositions and use
IT1150194B (it) * 1982-02-23 1986-12-10 Chiesi Farma Spa Formulazioni farmaceutiche ad attivita'antiinfiammatoria, analgesica,antipiretica e gastroprotettiva

Also Published As

Publication number Publication date
CA1218064A (en) 1987-02-17
NZ207913A (en) 1986-11-12
SG107587G (en) 1988-05-20
KR840008359A (ko) 1984-12-14
PT78432A (fr) 1984-05-01
FR2544718A1 (fr) 1984-10-26
AU561210B2 (en) 1987-04-30
HU194877B (en) 1988-03-28
ZA842672B (en) 1984-11-28
JPS59199676A (ja) 1984-11-12
IE57219B1 (en) 1992-06-03
PH18986A (en) 1985-11-29
ES531679A0 (es) 1984-12-16
IL71525A (en) 1987-11-30
AU2674884A (en) 1984-10-25
DK200884D0 (da) 1984-04-18
MY100483A (en) 1990-10-15
IL71525A0 (en) 1984-07-31
GB8409104D0 (en) 1984-05-16
KR880001477B1 (ko) 1988-08-13
US4595686A (en) 1986-06-17
YU65784A (en) 1986-10-31
ATE33639T1 (de) 1988-05-15
DK200884A (da) 1984-10-22
IE840843L (en) 1984-10-21
EP0129449A1 (fr) 1984-12-27
PT78432B (fr) 1986-05-27
DK157858B (da) 1990-02-26
EG17886A (en) 1991-03-30
ES8502111A1 (es) 1984-12-16
EP0129449B1 (fr) 1988-04-20
MA20097A1 (fr) 1984-12-31
AR240314A1 (es) 1990-03-30
GB2140008A (en) 1984-11-21
DE3470534D1 (en) 1988-05-26
HUT34188A (en) 1985-02-28
GR81476B (enExample) 1984-12-11
DK157858C (da) 1990-07-30
FR2544718B1 (fr) 1985-12-20

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee