GB2123833B - Steroid 1,2-dehydrogenation using dried microbial cells - Google Patents

Steroid 1,2-dehydrogenation using dried microbial cells

Info

Publication number
GB2123833B
GB2123833B GB08317422A GB8317422A GB2123833B GB 2123833 B GB2123833 B GB 2123833B GB 08317422 A GB08317422 A GB 08317422A GB 8317422 A GB8317422 A GB 8317422A GB 2123833 B GB2123833 B GB 2123833B
Authority
GB
United Kingdom
Prior art keywords
dehydrogenation
steroid
microbial cells
dried microbial
dried
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08317422A
Other versions
GB8317422D0 (en
GB2123833A (en
Inventor
Leo Aloysius Kominek
Holly Jo Wolf
Timothy Wendell Evans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/436,552 external-priority patent/US4524134A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB8317422D0 publication Critical patent/GB8317422D0/en
Publication of GB2123833A publication Critical patent/GB2123833A/en
Application granted granted Critical
Publication of GB2123833B publication Critical patent/GB2123833B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/02—Dehydrogenating; Dehydroxylating

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GB08317422A 1982-07-30 1983-06-27 Steroid 1,2-dehydrogenation using dried microbial cells Expired GB2123833B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40394982A 1982-07-30 1982-07-30
US06/436,552 US4524134A (en) 1982-07-30 1982-10-25 Process for preparing 1,2-dehydro steroids
US47543783A 1983-03-15 1983-03-15

Publications (3)

Publication Number Publication Date
GB8317422D0 GB8317422D0 (en) 1983-07-27
GB2123833A GB2123833A (en) 1984-02-08
GB2123833B true GB2123833B (en) 1986-06-11

Family

ID=27410563

Family Applications (2)

Application Number Title Priority Date Filing Date
GB08317422A Expired GB2123833B (en) 1982-07-30 1983-06-27 Steroid 1,2-dehydrogenation using dried microbial cells
GB08402640A Expired GB2131811B (en) 1982-07-30 1984-02-01 Microbial 1, 2-dehydrogenation of steroids

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB08402640A Expired GB2131811B (en) 1982-07-30 1984-02-01 Microbial 1, 2-dehydrogenation of steroids

Country Status (8)

Country Link
JP (2) JPH0614874B2 (en)
CH (1) CH657871A5 (en)
DD (1) DD213242A5 (en)
DE (1) DE3322120A1 (en)
FR (1) FR2531101B1 (en)
GB (2) GB2123833B (en)
IE (1) IE55533B1 (en)
NL (1) NL8302596A (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2568908B1 (en) * 1984-08-10 1986-12-26 Doris Dev Richesse Sous Marine OSCILLATING PLATFORM ON FLEXIBLE PILES FOR WORK AT SEA
US5506354A (en) * 1985-09-12 1996-04-09 The Upjohn Company Imidazolylpiperazinyl steroids
USRE35053E (en) * 1985-09-12 1995-10-10 The Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
ATE94212T1 (en) * 1987-03-12 1993-09-15 Upjohn Co 1-2 DEHYDRATION OF STEROID 21 ESTERS WITH A. SIMPLEX.
CN101346460B (en) * 2005-12-28 2014-05-07 味之素株式会社 Method for production of dried microorganism cell
HU227367B1 (en) * 2007-09-11 2011-04-28 Richter Gedeon Nyrt Method for producing 6-hydroxymethyl-1,4-androstadiene-3,17-dion
LT2805720T (en) 2008-05-28 2019-09-25 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of NF-KB for treatment of disease
CN102272304B (en) 2009-01-07 2013-10-23 三菱化学株式会社 Sterol side chain-cleaving enzyme protein and use thereof
WO2011127048A2 (en) 2010-04-05 2011-10-13 Validus Biopharma NON-HORMONAL STEROID MODULATORS OF NF-ĸB FOR TREATMENT OF DISEASE
US10799514B2 (en) 2015-06-29 2020-10-13 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of NF-kappa beta for treatment of disease
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB883500A (en) * 1958-09-15 1961-11-29 Wisconsin Alumni Res Found Improvements in a microbiological process for the preparation of steroids and ketones
FR1262182A (en) * 1960-07-01 1961-05-26 Olin Mathieson Process for selective dehydrogenation of the nucleus to steroids
US3087864A (en) * 1961-04-28 1963-04-30 American Cyanamid Co Process for the 1, 2-hydrogenation of steroids by the use of dried thalli
CH414063A (en) * 1962-11-23 1966-05-31 Eprova Ag X-ray contrast media
US3360439A (en) * 1964-08-19 1967-12-26 Squibb & Sons Inc Process for preparing 1-dehydro steroids
US3549498A (en) * 1968-04-02 1970-12-22 Squibb & Sons Inc 11alpha-substituted steroids and process
FR2285137A1 (en) * 1974-09-18 1976-04-16 Roussel Uclaf NEW 17-SPIROSULTIN STEROID DERIVATIVES, THE CORRESPONDING G-HYDROXYACIDS, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS A MEDICINAL PRODUCT
US4035236A (en) * 1975-10-24 1977-07-12 The Upjohn Company Process for preparing 9α-hydroxyandrostenedione
US4041055A (en) * 1975-11-17 1977-08-09 The Upjohn Company Process for the preparation of 17α-hydroxyprogesterones and corticoids from androstenes

Also Published As

Publication number Publication date
GB8317422D0 (en) 1983-07-27
DE3322120A1 (en) 1984-02-02
GB8402640D0 (en) 1984-03-07
FR2531101B1 (en) 1985-11-15
GB2131811A (en) 1984-06-27
DE3322120C2 (en) 1992-10-08
JPS5939299A (en) 1984-03-03
IE831767L (en) 1984-01-30
NL8302596A (en) 1984-02-16
CH657871A5 (en) 1986-09-30
DD213242A5 (en) 1984-09-05
GB2123833A (en) 1984-02-08
IE55533B1 (en) 1990-10-24
JPH0614874B2 (en) 1994-03-02
JPH06225792A (en) 1994-08-16
GB2131811B (en) 1986-06-11
FR2531101A1 (en) 1984-02-03
JPH0824596B2 (en) 1996-03-13

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years