GB2120662B - New azepinoindoles their production and pharmaceutical compositions containing them - Google Patents
New azepinoindoles their production and pharmaceutical compositions containing themInfo
- Publication number
- GB2120662B GB2120662B GB08312159A GB8312159A GB2120662B GB 2120662 B GB2120662 B GB 2120662B GB 08312159 A GB08312159 A GB 08312159A GB 8312159 A GB8312159 A GB 8312159A GB 2120662 B GB2120662 B GB 2120662B
- Authority
- GB
- United Kingdom
- Prior art keywords
- azepinoindoles
- new
- production
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH2806/82A CH649553A5 (de) | 1982-05-06 | 1982-05-06 | Azepinoindole und verfahren zu deren herstellung. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB8312159D0 GB8312159D0 (en) | 1983-06-08 |
| GB2120662A GB2120662A (en) | 1983-12-07 |
| GB2120662B true GB2120662B (en) | 1985-09-11 |
Family
ID=4242007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB08312159A Expired GB2120662B (en) | 1982-05-06 | 1983-05-04 | New azepinoindoles their production and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS58203993A (sv) |
| AU (1) | AU1425683A (sv) |
| BE (1) | BE896590A (sv) |
| CH (1) | CH649553A5 (sv) |
| DE (1) | DE3315467A1 (sv) |
| DK (1) | DK199883A (sv) |
| ES (1) | ES522008A0 (sv) |
| FI (1) | FI831475L (sv) |
| FR (1) | FR2526434A1 (sv) |
| GB (1) | GB2120662B (sv) |
| HU (1) | HU189275B (sv) |
| IL (1) | IL68576A0 (sv) |
| IT (1) | IT1197644B (sv) |
| NL (1) | NL8301552A (sv) |
| PT (1) | PT76632B (sv) |
| SE (1) | SE8302554L (sv) |
| ZA (1) | ZA833266B (sv) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8500370A (nl) * | 1984-02-22 | 1985-09-16 | Sandoz Ag | Diazepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten. |
| AU582564B2 (en) * | 1985-02-20 | 1989-04-06 | Sandoz Ltd. | 2,3,4,5-tetrahydro-11-phenyl-1H-``1,4``diazepino``1,7-a`` indoles, their production and pharmaceutical compositions containing them |
| PE20020510A1 (es) | 2000-09-20 | 2002-06-12 | Upjohn Co | DERIVADOS DE AZEPILO [4,5b] INDOLINA SUSTITUIDOS COMO LIGANDOS DE LOS RECEPTORES DE SEROTONINA (5-HT) |
| JP2005526691A (ja) * | 2001-08-08 | 2005-09-08 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 治療剤１Ｈ−ピリド［４，３−ｂ］インドール |
| BRPI0707183A2 (pt) * | 2006-01-19 | 2011-04-26 | Athersys Inc | composto, composição farmacêutica, e, método de tratar uma doença, distúrbio e/ou condição em um paciente |
| ES2523580T3 (es) | 2008-01-11 | 2014-11-27 | Albany Molecular Research, Inc. | Piridoindoles substituidos con (1-Azinona) |
| WO2011003021A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof |
| JP2012532144A (ja) | 2009-07-01 | 2012-12-13 | アルバニー モレキュラー リサーチ， インコーポレイテッド | アジノン置換アゼピノ［ｂ］インドールおよびピリド−ピロロ−アゼピンｍｃｈ−１拮抗薬、ならびにその作製方法および使用 |
| WO2011003007A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof |
| WO2011003012A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof |
| US8697700B2 (en) | 2010-12-21 | 2014-04-15 | Albany Molecular Research, Inc. | Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof |
| US8993765B2 (en) | 2010-12-21 | 2015-03-31 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0028381B1 (en) * | 1979-11-02 | 1985-04-10 | Sandoz Ag | Azepinoindoles, process for their production and pharmaceutical compositions containing them |
-
1982
- 1982-05-06 CH CH2806/82A patent/CH649553A5/de not_active IP Right Cessation
-
1983
- 1983-04-27 FR FR8307089A patent/FR2526434A1/fr active Pending
- 1983-04-28 BE BE1/10774A patent/BE896590A/fr not_active IP Right Cessation
- 1983-04-28 DE DE19833315467 patent/DE3315467A1/de not_active Withdrawn
- 1983-04-29 FI FI831475A patent/FI831475L/fi not_active Application Discontinuation
- 1983-05-02 ES ES522008A patent/ES522008A0/es active Granted
- 1983-05-03 NL NL8301552A patent/NL8301552A/nl not_active Application Discontinuation
- 1983-05-04 DK DK199883A patent/DK199883A/da not_active Application Discontinuation
- 1983-05-04 HU HU831531A patent/HU189275B/hu unknown
- 1983-05-04 SE SE8302554A patent/SE8302554L/sv not_active Application Discontinuation
- 1983-05-04 GB GB08312159A patent/GB2120662B/en not_active Expired
- 1983-05-04 IL IL68576A patent/IL68576A0/xx unknown
- 1983-05-04 PT PT76632A patent/PT76632B/pt unknown
- 1983-05-04 JP JP58078869A patent/JPS58203993A/ja active Pending
- 1983-05-05 AU AU14256/83A patent/AU1425683A/en not_active Abandoned
- 1983-05-06 ZA ZA833266A patent/ZA833266B/xx unknown
- 1983-05-06 IT IT48232/83A patent/IT1197644B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| ES8502440A1 (es) | 1985-01-01 |
| ZA833266B (en) | 1984-12-24 |
| IL68576A0 (en) | 1983-09-30 |
| GB2120662A (en) | 1983-12-07 |
| DK199883A (da) | 1983-11-07 |
| SE8302554L (sv) | 1983-11-07 |
| DK199883D0 (da) | 1983-05-04 |
| CH649553A5 (de) | 1985-05-31 |
| AU1425683A (en) | 1983-11-10 |
| GB8312159D0 (en) | 1983-06-08 |
| PT76632A (en) | 1983-06-01 |
| DE3315467A1 (de) | 1983-11-17 |
| SE8302554D0 (sv) | 1983-05-04 |
| PT76632B (en) | 1986-01-27 |
| FR2526434A1 (fr) | 1983-11-10 |
| FI831475A0 (fi) | 1983-04-29 |
| IT8348232A0 (it) | 1983-05-06 |
| JPS58203993A (ja) | 1983-11-28 |
| HU189275B (en) | 1986-06-30 |
| FI831475L (fi) | 1983-11-07 |
| NL8301552A (nl) | 1983-12-01 |
| BE896590A (fr) | 1983-10-28 |
| IT1197644B (it) | 1988-12-06 |
| ES522008A0 (es) | 1985-01-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |