GB2095252B - N-(substituted aminoalkanoyl) heterocyclic compounds - Google Patents
N-(substituted aminoalkanoyl) heterocyclic compoundsInfo
- Publication number
- GB2095252B GB2095252B GB8207770A GB8207770A GB2095252B GB 2095252 B GB2095252 B GB 2095252B GB 8207770 A GB8207770 A GB 8207770A GB 8207770 A GB8207770 A GB 8207770A GB 2095252 B GB2095252 B GB 2095252B
- Authority
- GB
- United Kingdom
- Prior art keywords
- heterocyclic compounds
- substituted aminoalkanoyl
- aminoalkanoyl
- substituted
- heterocyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24540781A | 1981-03-19 | 1981-03-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2095252A GB2095252A (en) | 1982-09-29 |
| GB2095252B true GB2095252B (en) | 1985-04-17 |
Family
ID=22926526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8207770A Expired GB2095252B (en) | 1981-03-19 | 1982-03-17 | N-(substituted aminoalkanoyl) heterocyclic compounds |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS57165355A (pt) |
| KR (1) | KR890001146B1 (pt) |
| AU (1) | AU558451B2 (pt) |
| BE (1) | BE892552A (pt) |
| CH (1) | CH658455A5 (pt) |
| DE (1) | DE3209708A1 (pt) |
| DK (1) | DK120982A (pt) |
| ES (3) | ES510498A0 (pt) |
| FI (1) | FI820974L (pt) |
| FR (1) | FR2502149A1 (pt) |
| GB (1) | GB2095252B (pt) |
| IE (1) | IE53076B1 (pt) |
| IL (1) | IL65247A (pt) |
| IN (1) | IN156096B (pt) |
| IT (1) | IT1150697B (pt) |
| NL (1) | NL8201066A (pt) |
| NO (1) | NO820903L (pt) |
| NZ (1) | NZ200047A (pt) |
| PH (1) | PH18657A (pt) |
| SE (1) | SE8201654L (pt) |
| ZA (1) | ZA821833B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3242599A1 (de) * | 1982-11-18 | 1984-05-24 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel |
| US4410520A (en) * | 1981-11-09 | 1983-10-18 | Ciba-Geigy Corporation | 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids |
| US4555502A (en) * | 1982-09-30 | 1985-11-26 | Merck & Co., Inc. | Aminoacyl-containing dipeptide derivatives useful as antihypertensives |
| US4410807A (en) * | 1982-03-26 | 1983-10-18 | Kay Industries, Inc. | Regulating device for polyphase electrical circuits |
| US4473575A (en) * | 1982-07-19 | 1984-09-25 | Ciba-Geigy Corporation | 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids |
| US4520025A (en) * | 1982-07-21 | 1985-05-28 | William H. Rorer, Inc. | Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses |
| DE3302125A1 (de) * | 1983-01-22 | 1984-07-26 | Boehringer Ingelheim KG, 6507 Ingelheim | Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung |
| FI841052A (fi) * | 1983-03-16 | 1984-09-17 | Usv Pharma Corp | Foereningar foer behandling av blodtryckssjukdomar. |
| DE3333454A1 (de) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern |
| DE3622297A1 (de) * | 1986-07-03 | 1988-01-07 | Basf Ag | Disazothiophenfarbstoffe |
| US5246943A (en) * | 1992-05-19 | 1993-09-21 | Warner-Lambert Company | Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties |
| ES2122941B1 (es) * | 1997-05-29 | 1999-07-01 | Esteve Quimica Sa | Procedimiento para la obtencion de quinapril clorhidrato y solvatos utiles para el aislamiento y purificacion de quinapril clorhidrato. |
| PT1333026E (pt) | 2002-01-30 | 2007-09-17 | Servier Lab | ''processo para a preparação de perindopril com elevado grau de pureza e intermediários úteis para a sua síntese'' |
| CA2510773C (en) | 2002-12-16 | 2010-04-13 | Lupin Limited | Crystalline form of quinapril hydrochloride and process for preparing the same |
| DE60321233D1 (de) * | 2003-02-28 | 2008-07-03 | Servier S A Lab | Verfahren zur herstellung von perindopril |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2503155A2 (fr) * | 1980-10-02 | 1982-10-08 | Science Union & Cie | Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme |
| EP0278530A3 (de) * | 1980-08-30 | 1989-08-02 | Hoechst Aktiengesellschaft | Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung |
| US4344949A (en) * | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
| GB2086390B (en) * | 1980-11-03 | 1984-06-06 | Ciba Geigy Ag | 1-carboxy-azaalkanoylindoline-2-carboxylic acids process for their manufacture pharmaceutical preparations containing these compounds and their therapeutic application |
-
1982
- 1982-03-08 IN IN265/CAL/82A patent/IN156096B/en unknown
- 1982-03-15 PH PH26998A patent/PH18657A/en unknown
- 1982-03-15 IL IL65247A patent/IL65247A/xx unknown
- 1982-03-15 NL NL8201066A patent/NL8201066A/nl not_active Application Discontinuation
- 1982-03-16 SE SE8201654A patent/SE8201654L/xx not_active Application Discontinuation
- 1982-03-16 AU AU81584/82A patent/AU558451B2/en not_active Ceased
- 1982-03-17 DE DE19823209708 patent/DE3209708A1/de not_active Withdrawn
- 1982-03-17 ES ES510498A patent/ES510498A0/es active Granted
- 1982-03-17 GB GB8207770A patent/GB2095252B/en not_active Expired
- 1982-03-18 BE BE0/207610A patent/BE892552A/fr not_active IP Right Cessation
- 1982-03-18 KR KR8201157A patent/KR890001146B1/ko active
- 1982-03-18 DK DK120982A patent/DK120982A/da not_active Application Discontinuation
- 1982-03-18 NZ NZ200047A patent/NZ200047A/en unknown
- 1982-03-18 IT IT20259/82A patent/IT1150697B/it active
- 1982-03-18 NO NO820903A patent/NO820903L/no unknown
- 1982-03-18 ZA ZA821833A patent/ZA821833B/xx unknown
- 1982-03-18 CH CH1691/82A patent/CH658455A5/de not_active IP Right Cessation
- 1982-03-18 JP JP57041801A patent/JPS57165355A/ja active Pending
- 1982-03-19 FI FI820974A patent/FI820974L/fi not_active Application Discontinuation
- 1982-03-19 FR FR8204738A patent/FR2502149A1/fr active Granted
- 1982-03-19 IE IE635/82A patent/IE53076B1/en unknown
-
1983
- 1983-03-16 ES ES521030A patent/ES521030A0/es active Granted
- 1983-03-16 ES ES521031A patent/ES8501363A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2502149A1 (fr) | 1982-09-24 |
| NO820903L (no) | 1982-09-20 |
| ES8404317A1 (es) | 1984-05-16 |
| FI820974L (fi) | 1982-09-20 |
| NL8201066A (nl) | 1982-10-18 |
| ZA821833B (en) | 1983-01-26 |
| ES521031A0 (es) | 1984-12-01 |
| KR830009065A (ko) | 1983-12-17 |
| ES521030A0 (es) | 1984-05-16 |
| IE820635L (en) | 1982-09-19 |
| GB2095252A (en) | 1982-09-29 |
| AU8158482A (en) | 1982-09-23 |
| JPS57165355A (en) | 1982-10-12 |
| ES8307718A1 (es) | 1983-08-01 |
| DE3209708A1 (de) | 1982-10-21 |
| IN156096B (pt) | 1985-05-11 |
| ES510498A0 (es) | 1983-08-01 |
| KR890001146B1 (ko) | 1989-04-25 |
| IT1150697B (it) | 1986-12-17 |
| FR2502149B1 (pt) | 1985-01-18 |
| SE8201654L (sv) | 1982-09-20 |
| AU558451B2 (en) | 1987-01-29 |
| BE892552A (fr) | 1982-09-20 |
| NZ200047A (en) | 1985-07-12 |
| IT8220259A0 (it) | 1982-03-18 |
| IE53076B1 (en) | 1988-06-08 |
| ES8501363A1 (es) | 1984-12-01 |
| IL65247A0 (en) | 1982-05-31 |
| IL65247A (en) | 1987-07-31 |
| CH658455A5 (de) | 1986-11-14 |
| PH18657A (en) | 1985-08-29 |
| DK120982A (da) | 1982-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |