GB2054371B - Long-acting parenteral compositions of haloperidol and bromperidol derivatives - Google Patents

Long-acting parenteral compositions of haloperidol and bromperidol derivatives

Info

Publication number
GB2054371B
GB2054371B GB8018117A GB8018117A GB2054371B GB 2054371 B GB2054371 B GB 2054371B GB 8018117 A GB8018117 A GB 8018117A GB 8018117 A GB8018117 A GB 8018117A GB 2054371 B GB2054371 B GB 2054371B
Authority
GB
United Kingdom
Prior art keywords
bromperidol
haloperidol
derivatives
long
parenteral compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8018117A
Other languages
English (en)
Other versions
GB2054371A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of GB2054371A publication Critical patent/GB2054371A/en
Application granted granted Critical
Publication of GB2054371B publication Critical patent/GB2054371B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB8018117A 1979-06-28 1980-06-03 Long-acting parenteral compositions of haloperidol and bromperidol derivatives Expired GB2054371B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8082679A JPS568318A (en) 1979-06-28 1979-06-28 Non oral long acting composition of haloperidol and bromperidol derivative

Publications (2)

Publication Number Publication Date
GB2054371A GB2054371A (en) 1981-02-18
GB2054371B true GB2054371B (en) 1983-08-03

Family

ID=13729223

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8018117A Expired GB2054371B (en) 1979-06-28 1980-06-03 Long-acting parenteral compositions of haloperidol and bromperidol derivatives

Country Status (9)

Country Link
JP (1) JPS568318A (enExample)
BE (1) BE883994A (enExample)
CY (1) CY1255A (enExample)
DE (1) DE3024305A1 (enExample)
FR (1) FR2460932A1 (enExample)
GB (1) GB2054371B (enExample)
HK (1) HK83384A (enExample)
KE (1) KE3427A (enExample)
NL (1) NL190775C (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8621892D0 (en) * 1986-09-11 1986-10-15 Lundbeck & Co As H Organic compound
DK238190D0 (da) * 1990-10-03 1990-10-03 Lundbeck & Co As H Depotderivater
DK0669128T3 (da) * 1992-11-17 2000-06-19 Yoshitomi Pharmaceutical Sustained-release mikrosfære indeholdende antipsykotikum og fremgangsmåde til at fremstille samme
AU5157798A (en) 1996-10-31 1998-05-22 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Sustained-release derivatives of hydroxylated analogs of substituted 1-{2{bis(aryl)methoxy}ethyl}-piperazines and -homopiperazines and their use as noncompetitive antagonists of dopamine reuptake
RU2178297C1 (ru) * 2001-02-02 2002-01-20 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Фармацевтическая композиция, обладающая антипсихотическим и противорвотным действием, и способ ее получения
CA2586761A1 (en) 2004-11-10 2006-05-18 Genzyme Corporation Methods of treating diabetes mellitus
EP2032134B1 (en) 2006-05-09 2015-06-24 Genzyme Corporation Methods of treating fatty liver disease comprising inhibiting glucosphingolipid synthesis
US8304447B2 (en) 2007-05-31 2012-11-06 Genzyme Corporation 2-acylaminopropoanol-type glucosylceramide synthase inhibitors
KR20160085917A (ko) 2007-10-05 2016-07-18 젠자임 코포레이션 세라마이드 유도체로 다낭성 신장질환을 치료하는 방법
WO2010014554A1 (en) 2008-07-28 2010-02-04 Genzyme Corporation Glucosylceramide synthase inhibition for the treatment of collapsing glomerulopathy and other glomerular disease
US8309593B2 (en) 2008-10-03 2012-11-13 Genzyme Corporation 2-acylaminopropoanol-type glucosylceramide synthase inhibitors
MX358344B (es) 2011-03-18 2018-08-15 Alkermes Pharma Ireland Ltd Composiciones farmaceuticas que comprenden un antipsicotico insoluble en agua y esteres de sorbitan.
CN103301461B (zh) * 2012-03-08 2018-09-07 江苏豪森药业集团有限公司 一种长效注射制剂及其制备方法和用途
EP2827868B8 (en) 2012-03-19 2019-12-18 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising fatty acid esters
NZ630428A (en) 2012-03-19 2017-02-24 Alkermes Pharma Ireland Ltd Pharmaceutical compositions comprising benzyl alcohol
AU2013235523B9 (en) 2012-03-19 2018-01-04 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising glycerol esters
WO2014080285A2 (en) 2012-09-19 2014-05-30 Alkermes Pharma Ireland Limited Pharmaceutical compositions having improved storage stability
CN110368360A (zh) 2014-03-20 2019-10-25 奥克梅斯制药爱尔兰有限公司 具有增加的注射速度的阿立哌唑制剂
WO2019173230A1 (en) 2018-03-05 2019-09-12 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
CN113117092A (zh) * 2020-01-14 2021-07-16 中国科学院上海药物研究所 一种非水缓释递药系统
HUP2100259A1 (hu) 2021-07-07 2023-01-28 Richter Gedeon Nyrt Cariprazine tartalmú szabályozott hatóanyag-leadású injekciós készítmények

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3408356A (en) * 1965-08-31 1968-10-29 Squibb & Sons Inc Long chain esters of 4'-fluoro-4-[4-hydroxy-4-(alpha, alpha, alpha-trifluorotolyl)piperi-dino]butyrophenone and the like
DE1695194A1 (de) * 1966-07-11 1971-03-18 Hoffmann La Roche Verfahren zur Herstellung von Piperidinderivaten
US3850935A (en) * 1971-10-16 1974-11-26 Sumitomo Chemical Co Process for producing piperidine derivatives by degrading quaternary piperidinium salts

Also Published As

Publication number Publication date
DE3024305A1 (de) 1981-01-22
BE883994A (fr) 1980-12-29
FR2460932B1 (enExample) 1984-11-16
JPS568318A (en) 1981-01-28
NL8003583A (nl) 1980-12-30
CY1255A (en) 1984-08-31
GB2054371A (en) 1981-02-18
KE3427A (en) 1984-08-10
DE3024305C2 (enExample) 1989-12-07
NL190775C (nl) 1994-08-16
NL190775B (nl) 1994-03-16
FR2460932A1 (fr) 1981-01-30
HK83384A (en) 1984-11-09

Similar Documents

Publication Publication Date Title
GB2054371B (en) Long-acting parenteral compositions of haloperidol and bromperidol derivatives
NZ192653A (en) 4-substituted piperidino-alkanol derivatives and pharmaceutical compositions containing them
NZ189253A (en) Amine derivatives and pharmaceutical compositions
PH17391A (en) Triazolthioalkyl substituted pleuromuilin derivatives and compositions thereof
NZ193798A (en) 3-thiovinyl-cephalosporin derivatives and pharmaceutical compositions
PH15980A (en) 2-imidazoline derivatives and pharmaceutical composition
NZ187272A (en) Alkylenediamine derivatives and pharmaceutical compositions
ZA803038B (en) Novel 3-vinyl-cephalosporin derivatives and their preparation
NZ194348A (en) Fluorinated methyl-beta-alanine derivatives and pharmaceutical compositions
NZ195368A (en) Homoserine derivatives and pesticidal compositions
NZ186335A (en) Oxadizolopyrimidine derivatives and pharmazeutical compositions
GB2050349B (en) Isonicotinoyl derivatives of aminoacids
DE3064789D1 (en) New 25-hydroxy-24-oxocholestane derivatives and preparation thereof
GB2055370B (en) Ergol-8-ene and ergoline derivatives
GB2000772B (en) Derivatives of ergoline - 2 - thioethers and sulphoxides
PH15451A (en) Benzothiazole derivatives and compositions containing same
PH16220A (en) Pyrro-lidine derivatives and pharmaceutical compositions thereof
GB2001980B (en) Dioxazocine derivatives their preparation and compositions containing them
JPS5639067A (en) Pyrrolidineedione derivatives and mildewcidal composition containing them
IL53374A (en) Acaricidal compositions comprising certain imidazoline derivatives and two such novel derivatives
NZ185779A (en) Derivatives of ortho-aminoacetophenone and pharaceutical compositions
GB2065645B (en) Derivatives of 2-aminoethanol
GB2044258B (en) Quinoline derivatives useful as antioxidants their preparation and compositions containing them
JPS5683479A (en) Novel oxybenztriazole derivatives* their manufacture and their use
IL61626A0 (en) 6-pyridinyl-pyridazine derivatives and pharmalceutical compositions containing them

Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20000602