GB2034323B - Production of dna comprising the b hepatitis viral genome - Google Patents

Production of dna comprising the b hepatitis viral genome

Info

Publication number
GB2034323B
GB2034323B GB7943491A GB7943495A GB2034323B GB 2034323 B GB2034323 B GB 2034323B GB 7943491 A GB7943491 A GB 7943491A GB 7943495 A GB7943495 A GB 7943495A GB 2034323 B GB2034323 B GB 2034323B
Authority
GB
United Kingdom
Prior art keywords
dna
production
viral genome
hepatitis viral
hepatitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7943491A
Other languages
English (en)
Other versions
GB2034323A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Institut Pasteur
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM, Institut Pasteur filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Publication of GB2034323A publication Critical patent/GB2034323A/en
Priority to EP80304259A priority Critical patent/EP0030804B1/en
Priority to AT80304259T priority patent/ATE5076T1/de
Priority to DE8080304259T priority patent/DE3065399D1/de
Priority to GB8038588A priority patent/GB2065646B/en
Priority to US06/212,897 priority patent/US4343934A/en
Priority to ZA00807578A priority patent/ZA807578B/xx
Priority to CA000366213A priority patent/CA1154760A/en
Priority to AU65151/80A priority patent/AU538458B2/en
Priority to IL61667A priority patent/IL61667A/xx
Priority to MX80101456U priority patent/MX6561E/es
Priority to YU3169/80A priority patent/YU40784B/xx
Priority to PT72207A priority patent/PT72207B/pt
Priority to KR1019800004825A priority patent/KR840000156B1/ko
Priority to ES497862A priority patent/ES497862A0/es
Priority to NZ195867A priority patent/NZ195867A/xx
Priority to IE2658/80A priority patent/IE50634B1/en
Priority to PH24997A priority patent/PH17320A/en
Priority to DK537880A priority patent/DK157196C/da
Priority to JP17967580A priority patent/JPS5697297A/ja
Priority to NO803848A priority patent/NO149242C/no
Priority to GR63714A priority patent/GR72757B/el
Priority to AR283700A priority patent/AR229023A1/es
Priority to FI803959A priority patent/FI69470C/fi
Application granted granted Critical
Publication of GB2034323B publication Critical patent/GB2034323B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GB7943491A 1978-12-18 1979-12-18 Production of dna comprising the b hepatitis viral genome Expired GB2034323B (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
EP80304259A EP0030804B1 (en) 1979-12-18 1980-11-27 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
AT80304259T ATE5076T1 (de) 1979-12-18 1980-11-27 Kristallin-4,1',6'-trichlor-4,1',6'-trideoxygalactosucrose.
DE8080304259T DE3065399D1 (en) 1979-12-18 1980-11-27 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
GB8038588A GB2065646B (en) 1979-12-18 1980-12-02 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
US06/212,897 US4343934A (en) 1979-12-18 1980-12-04 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
ZA00807578A ZA807578B (en) 1979-12-18 1980-12-04 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
CA000366213A CA1154760A (en) 1979-12-18 1980-12-05 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy- galactosucrose
AU65151/80A AU538458B2 (en) 1979-12-18 1980-12-08 Crystalline 4,1:,6:-trichloro-4,1:,61-trideoxygalactosucros
IL61667A IL61667A (en) 1979-12-18 1980-12-09 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose,method for the preparation thereof and comestible compositions containing it
MX80101456U MX6561E (es) 1979-12-18 1980-12-16 Procedimiento para la preparacion de 4,1,6-tricloro-4,1',6'-tridesoxi-galactosacarosa cristalina anhidra
YU3169/80A YU40784B (en) 1979-12-18 1980-12-16 Process for preparing 4,1'6',-trichloro-4,1,6'-trideoxy-galaceto saccharose
PT72207A PT72207B (en) 1979-12-18 1980-12-16 Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose crystalline
KR1019800004825A KR840000156B1 (ko) 1979-12-18 1980-12-17 4, 1', 6'-트리클로로-4, 1', 6'-트리데옥시-갈락토슈크로오스 결정의 제조방법
ES497862A ES497862A0 (es) 1979-12-18 1980-12-17 Un procedimiento de preparacion de 4,1',6'-tricloro-4,1',6' tridesoxigalactosacarosa
NZ195867A NZ195867A (en) 1979-12-18 1980-12-17 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose and use as sweetener
IE2658/80A IE50634B1 (en) 1979-12-18 1980-12-17 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
PH24997A PH17320A (en) 1979-12-18 1980-12-17 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
DK537880A DK157196C (da) 1979-12-18 1980-12-17 Krystallinsk 4,1',6'-trichlor-4,1',6,-tridesoxygalactosaccharose, anvendelse deraf som soedemiddel og soedemiddel indeholdende denne
JP17967580A JPS5697297A (en) 1979-12-18 1980-12-18 Crystalline 4*1**6**trichloroo4*1**6** trideoxygalactose
NO803848A NO149242C (no) 1979-12-18 1980-12-18 Krystallinsk, 4,1`,6`-triklor-4,1`,6`-trideoksygalaktosukrose
GR63714A GR72757B (enrdf_load_stackoverflow) 1979-12-18 1980-12-18
AR283700A AR229023A1 (es) 1979-12-18 1980-12-18 Nueva forma cristalina de 4,1',6'-tricloro-4,1',6'-tridesoxigalacto sucrosa util como edulcorante y composiciones edulcorantes que la contienen
FI803959A FI69470C (fi) 1979-12-18 1980-12-18 Kristallisk 4,1',6'-triklor-4,1',6'-trideoxi-galaktosackaros

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7835588A FR2444713A1 (fr) 1978-12-18 1978-12-18 Procede de production d'un adn comprenant le genome du virus de l'hepatite b et vecteur le comportant

Publications (2)

Publication Number Publication Date
GB2034323A GB2034323A (en) 1980-06-04
GB2034323B true GB2034323B (en) 1983-01-12

Family

ID=9216265

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7943491A Expired GB2034323B (en) 1978-12-18 1979-12-18 Production of dna comprising the b hepatitis viral genome

Country Status (6)

Country Link
BE (1) BE880670A (enrdf_load_stackoverflow)
CH (1) CH646456A5 (enrdf_load_stackoverflow)
DE (1) DE2950995A1 (enrdf_load_stackoverflow)
FR (1) FR2444713A1 (enrdf_load_stackoverflow)
GB (1) GB2034323B (enrdf_load_stackoverflow)
OA (1) OA06416A (enrdf_load_stackoverflow)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
US6270955B1 (en) 1978-12-22 2001-08-07 Biogen, Inc. Pharmaceutical compositions and methods for producing antibodies to hepatitis b virus and kits and methods for detecting antibodies to hepatitis b virus
NO794196L (no) * 1978-12-22 1980-06-24 Biogen Nv Fremgangsmaate ved fremstilling av et rekombinert dna molekyl
EP0182442B2 (en) * 1978-12-22 1996-04-03 Biogen, Inc. Recombinant DNA molecules and their method of production
US5196194A (en) * 1979-05-24 1993-03-23 The Regents Of The University Of California Vaccines containing Hepatitis B S-protein
IE52036B1 (en) * 1979-05-24 1987-05-27 Univ California Non-passageable viruses
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
EP0038765B1 (fr) * 1980-04-22 1987-09-02 Institut Pasteur Vaccin contre l'hépatite virale B, procédé et cellules eucaryotes transformées pour la production de ce vaccin
US4393133A (en) * 1980-06-12 1983-07-12 The Wistar Institute Of Anatomy And Biology Human hepatoma derived cell line, process for preparation thereof, and uses therefor
US5145782A (en) * 1980-12-08 1992-09-08 The Regents Of The University Of California DNA expression vector suitable for direct expression of a foreign gene
US4446237A (en) * 1981-03-27 1984-05-01 Life Technologies, Inc. Method for detection of a suspect viral deoxyribonucleic acid in an acellular biological fluid
EP0062286A1 (en) * 1981-03-31 1982-10-13 Albert Einstein College Of Medicine Of Yeshiva University Diagnostic test for hepatitis B virus
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
US4769238A (en) 1981-08-04 1988-09-06 The Regents Of The University Of California Synthesis of human virus antigens by yeast
ZW18282A1 (en) 1981-08-31 1983-03-23 Genentech Inc Preparation of polypeptides in vertebrate cell culture
US4803164A (en) * 1981-08-31 1989-02-07 Genentech, Inc. Preparation of hepatitis b surface antigen in yeast
AU8746582A (en) * 1981-09-02 1983-03-10 Biogen N.V. Hepatitis b virus e type antigen
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
US4480040A (en) * 1981-12-03 1984-10-30 The United States Of America As Represented By The Secretary Of Agriculture Sensitive and rapid diagnosis of viroid diseases and viruses
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
USRE35491E (en) * 1982-11-04 1997-04-08 The Regents Of The University Of California Methods and compositions for detecting human tumors
US4699877A (en) * 1982-11-04 1987-10-13 The Regents Of The University Of California Methods and compositions for detecting human tumors
US4820642A (en) * 1983-04-04 1989-04-11 The Regents Of The University Of California Amplified expression vector
FR2560995B1 (fr) * 1984-03-07 1988-02-19 Pasteur Institut Reactifs et necessaires pour le dosage quantitatif d'un acide nucleique viral dans un milieu biologique et procede de dosage de cet acide nucleique viral
US5780036A (en) * 1991-08-26 1998-07-14 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepattis B virus
US6607727B1 (en) 1991-08-26 2003-08-19 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus
ATE199158T1 (de) * 1991-12-23 2001-02-15 Bayer Ag Hbv amplifizierungssonden zur verwendung in hybridisierungssandwichassay in der lösungsphase
US6235288B1 (en) 1992-08-26 2001-05-22 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus
WO2000077179A2 (en) 1999-06-16 2000-12-21 Icos Corporation Human poly(adp-ribose) polymerase 2 materials and methods
CA2427820A1 (en) 2000-11-01 2002-06-13 Elusys Therapeutics, Inc. Method of producing biospecific molecules by protein trans-splicing
CA2605701C (en) 2005-04-29 2015-12-08 Rockefeller University Human micrornas and methods for inhibiting same
RS51840B (en) 2005-09-01 2012-02-29 Celgene Corporation IMMUNOLOGICAL APPLICATIONS OF IMMUNOMODULATORY UNITS FOR VACCINE AND FOR INFECTIOUS DISEASE THERAPY
WO2009002562A2 (en) 2007-06-27 2008-12-31 Marine Polymer Technologies, Inc. Complexes of il-15 and il-15ralpha and uses thereof
US20110262485A1 (en) 2008-08-04 2011-10-27 University Of Miami Sting (stimulator of interferon genes), a regulator of innate immune responses
US8691502B2 (en) 2008-10-31 2014-04-08 Tremrx, Inc. T-cell vaccination with viral vectors via mechanical epidermal disruption
WO2010085660A2 (en) 2009-01-23 2010-07-29 Roger Williams Hospital Viral vectors encoding multiple highly homologous non-viral polypeptides and the use of same
US9216189B2 (en) 2010-01-25 2015-12-22 Icahn School Of Medicine At Mount Sinai Antibodies which bind type I cannabinoid receptor/angiotensis II receptor heteromers
WO2012151272A2 (en) 2011-05-02 2012-11-08 Tremrx, Inc. T-cell vaccination with viral vectors via mechanical epidermal disruption
JP6253596B2 (ja) 2012-02-16 2017-12-27 ザ ペン ステイト リサーチ ファンデーション アシル補酵素ａ：リゾカルジオリピン・アシル基転移酵素１（ａｌｃａｔ１）の発現、機能または活性の阻害物質を同定する方法
CN104869987B (zh) 2012-09-07 2020-10-16 麻省眼耳医院 用于再生毛细胞和/或支持细胞的方法及组合物
ES2747997T3 (es) 2012-10-24 2020-03-12 Novartis Ag Formas de IL-15R alfa, células que expresan formas de IL-15R alfa, y usos terapéuticos de IL-15R alfa y complejos IL-15/IL-15R alfa
US10335460B2 (en) 2014-07-29 2019-07-02 Novartis Ag IL-15 and IL-15Rα heterodimer dose escalation regimens for treating conditions
US10258697B2 (en) 2014-10-29 2019-04-16 Massachusetts Eye And Ear Infirmary Efficient delivery of therapeutic molecules in vitro and in vivo
WO2016069906A1 (en) 2014-10-29 2016-05-06 Massachusetts Eye And Ear Infirmary Efficient delivery of therapeutic molecules to cells of the inner ear
EP3851120A4 (en) 2018-09-11 2022-04-27 Shanghai Public Health Clinical Center Immunogen for broad-spectrum influenza vaccine and application thereof
US11786592B2 (en) 2021-05-19 2023-10-17 The University Of Hong Kong Compositions of cardiolipin adjuvants and methods of use thereof
WO2023077147A2 (en) 2021-11-01 2023-05-04 Pellis Therapeutics, Inc. T-cell vaccines for patients with reduced humoral immunity
WO2023220283A1 (en) 2022-05-12 2023-11-16 Pellis Therapeutics, Inc. Poxvirus adjuvant for t-cell vaccination

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment
DE2712615A1 (de) * 1977-03-18 1978-09-21 Max Planck Gesellschaft Verfahren zur herstellung von filamentoesen phagen als vektor fuer synthetische rekombinate

Also Published As

Publication number Publication date
CH646456A5 (fr) 1984-11-30
OA06416A (fr) 1981-09-30
DE2950995C2 (enrdf_load_stackoverflow) 1991-05-02
DE2950995A1 (de) 1980-07-24
BE880670A (fr) 1980-06-18
FR2444713A1 (fr) 1980-07-18
GB2034323A (en) 1980-06-04
FR2444713B1 (enrdf_load_stackoverflow) 1981-02-06

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Legal Events

Date Code Title Description
CTFF Supplementary protection certificate filed

Free format text: SPC/GB93/162, 930702

CTFG Supplementary protection certificate granted

Free format text: SPC/GB93/162, 930702 SECOND APPLICANT:INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, EXPIRES:YYYYMMDD

CTFW Application to withdraw or offer to surrender a supplementary protection certificate

Free format text: SPC/GB93/162

PE20 Patent expired after termination of 20 years

Effective date: 19991217