GB2027694B - Substituted 4-aryl-2,5-dihydro-furan-2-ones and 4-aryl-1,5-dihydro-2h-pyrrol-2-ones and pharmaceutical compositions containing such compounds - Google Patents

Substituted 4-aryl-2,5-dihydro-furan-2-ones and 4-aryl-1,5-dihydro-2h-pyrrol-2-ones and pharmaceutical compositions containing such compounds

Info

Publication number
GB2027694B
GB2027694B GB7923561A GB7923561A GB2027694B GB 2027694 B GB2027694 B GB 2027694B GB 7923561 A GB7923561 A GB 7923561A GB 7923561 A GB7923561 A GB 7923561A GB 2027694 B GB2027694 B GB 2027694B
Authority
GB
United Kingdom
Prior art keywords
dihydro
aryl
ones
pyrrol
furan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7923561A
Other languages
English (en)
Other versions
GB2027694A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf AG
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19782829414 external-priority patent/DE2829414A1/de
Priority claimed from DE19792912951 external-priority patent/DE2912951A1/de
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Publication of GB2027694A publication Critical patent/GB2027694A/en
Application granted granted Critical
Publication of GB2027694B publication Critical patent/GB2027694B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/38—2-Pyrrolones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58—One oxygen atom, e.g. butenolide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
GB7923561A 1978-07-05 1979-07-05 Substituted 4-aryl-2,5-dihydro-furan-2-ones and 4-aryl-1,5-dihydro-2h-pyrrol-2-ones and pharmaceutical compositions containing such compounds Expired GB2027694B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782829414 DE2829414A1 (de) 1978-07-05 1978-07-05 Substituierte 4-aryl-2,5-dihydrofuran- 2-one und verfahren zu deren herstellung
DE19792912951 DE2912951A1 (de) 1979-03-31 1979-03-31 Substituierte 4-aryl-2,5-dihydro- furan-2-one und 4-aryl-1,5-dihydro-2h- pyrrol-2-one und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
GB2027694A GB2027694A (en) 1980-02-27
GB2027694B true GB2027694B (en) 1983-01-06

Family

ID=25774894

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7923561A Expired GB2027694B (en) 1978-07-05 1979-07-05 Substituted 4-aryl-2,5-dihydro-furan-2-ones and 4-aryl-1,5-dihydro-2h-pyrrol-2-ones and pharmaceutical compositions containing such compounds

Country Status (8)

Country Link
AT (1) AT377984B (fr)
CA (1) CA1133494A (fr)
CH (1) CH641451A5 (fr)
FR (1) FR2430422A1 (fr)
GB (1) GB2027694B (fr)
IT (1) IT1122012B (fr)
NL (1) NL7905218A (fr)
SE (1) SE7905862L (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2356153A (en) * 1941-03-21 1944-08-22 Lilly Co Eli beta-substituted-delta alpha,beta-gamma-butyrolactones and methods of preparing them
DE1920176A1 (de) * 1969-04-21 1970-10-22 Thomae Gmbh Dr K Neues Verfahren zur Herstellung von Hydroxycrotonsaeurelaktonen
FR2132570B1 (fr) * 1971-04-09 1974-08-02 Lipha

Also Published As

Publication number Publication date
IT7924101A0 (it) 1979-07-04
FR2430422B1 (fr) 1982-12-31
ATA466679A (de) 1984-10-15
IT1122012B (it) 1986-04-23
CA1133494A (fr) 1982-10-12
NL7905218A (nl) 1980-01-08
CH641451A5 (de) 1984-02-29
SE7905862L (sv) 1980-01-06
FR2430422A1 (fr) 1980-02-01
AT377984B (de) 1985-05-28
GB2027694A (en) 1980-02-27

Similar Documents

Publication Publication Date Title
DE2963320D1 (en) Ergoline compounds, their preparation and pharmaceutical compositions containing them
ZA791732B (en) Carbazolyl-(4)-oxypropanolamine derivatives,preparation thereof and pharmaceutical compositions containing these compounds
SG3185G (en) Compositions containing 1,3-dimethyl-5-aminoadamantane
IL58123A (en) 4,5-diaryl-2-nitroimidazoles,their preparation and pharmaceutical compositions containing them
IL56992A (en) N-heterocyclyl-4-piperidinamines,their preparation and pharmaceutical compositions containing them
GB2103203B (en) 1,4-dihydropyridines, their preparation and pharmaceutical compositions containing them
IL58478A0 (en) Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines
NZ189684A (en) Substituted 2-phenylimino-imidazolidines pharmaceutical compositions
DE2965287D1 (en) Bis-imidazoles, their preparation and pharmaceutical compositions containing them
IL58415A (en) Substituted octahydro-7-phenylquinolizines,their manufacture and pharmaceutical compositions containing them
ZA792042B (en) Substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof and pharmaceutical compositions containing them
EP0018417A4 (fr) Nouveaux derives de piperidine et compositions pharmaceutiques les contenant.
NZ192021A (en) Pharmaceutical compositions containing aryltrifluoroethanols
IL56686A0 (en) Acylaminoalkyl-syanoguanidines,their preparation and pharmaceutical compositions containing them
IL57891A (en) Alkylthiophenoxyalkylamines,their preparation and pharmaceutical compositions containing them
NZ189899A (en) Dilignols and dilignol-type compounds pharmaceutical compositions
IL56884A0 (en) Jungicidal compositions containing isothiouoniom phosphithes,certain such novel compound and their preparation
IL57754A0 (en) Benzopyranotriazoles,their preparation and pharmaceutical compositions containing them
IL57720A0 (en) Phenylpiperidine derivatives,their preparation and pharmaceutical compositions containing them
IL57854A0 (en) Substituted 2-phenylamino-imidazoline-(2)-derivatives,their preparation and pharmaceutical compositions containing them
IL58229A (en) Substituted benzylidene-benzofuran-3-(2h)-one compounds,their preparation and pharmaceutical compositions containing them
HK12384A (en) Novel veratramides,their preparation and pharmaceutical compositions containing them
IL57882A (en) 2-thiophenecarboxamido-alkyl-mercaptans and pharmaceutical compositions containing them
GB2024818B (en) Phenathrenederivatives, their preparation and pharmaceutical compositions containing them
IL56962A (en) Substituted n-iminomethyl-piperidines,their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee