GB202107994D0 - Treatment of cancer - Google Patents

Treatment of cancer

Info

Publication number
GB202107994D0
GB202107994D0 GBGB2107994.2A GB202107994A GB202107994D0 GB 202107994 D0 GB202107994 D0 GB 202107994D0 GB 202107994 A GB202107994 A GB 202107994A GB 202107994 D0 GB202107994 D0 GB 202107994D0
Authority
GB
United Kingdom
Prior art keywords
cancer
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2107994.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kymab Ltd
Original Assignee
Kymab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kymab Ltd filed Critical Kymab Ltd
Priority to GBGB2107994.2A priority Critical patent/GB202107994D0/en
Publication of GB202107994D0 publication Critical patent/GB202107994D0/en
Priority to CA3221115A priority patent/CA3221115A1/en
Priority to TW111120874A priority patent/TW202313110A/zh
Priority to IL308998A priority patent/IL308998A/en
Priority to EP22731296.4A priority patent/EP4347648A1/en
Priority to AU2022284342A priority patent/AU2022284342A1/en
Priority to PCT/GB2022/051413 priority patent/WO2022254227A1/en
Priority to JP2023574355A priority patent/JP2024520638A/ja
Priority to CN202280040129.8A priority patent/CN117580861A/zh
Priority to KR1020247000037A priority patent/KR20240017054A/ko
Priority to US18/510,228 priority patent/US20240190964A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GBGB2107994.2A 2021-06-04 2021-06-04 Treatment of cancer Ceased GB202107994D0 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
GBGB2107994.2A GB202107994D0 (en) 2021-06-04 2021-06-04 Treatment of cancer
KR1020247000037A KR20240017054A (ko) 2021-06-04 2022-06-06 항-icos 항체를 사용한 pd-l1 음성 또는 저발현 암의 치료
EP22731296.4A EP4347648A1 (en) 2021-06-04 2022-06-06 Treatment of pd-l1 negative or low expressing cancer with anti-icos antibodies
TW111120874A TW202313110A (zh) 2021-06-04 2022-06-06 癌症之治療
IL308998A IL308998A (en) 2021-06-04 2022-06-06 Treatment of PD-L1 negative cancer or cancer with low expression with antibodies against ICOS
CA3221115A CA3221115A1 (en) 2021-06-04 2022-06-06 Treatment of pd-l1 negative or low expressing cancer with anti-icos antibodies
AU2022284342A AU2022284342A1 (en) 2021-06-04 2022-06-06 Treatment of pd-l1 negative or low expressing cancer with anti-icos antibodies
PCT/GB2022/051413 WO2022254227A1 (en) 2021-06-04 2022-06-06 Treatment of pd-l1 negative or low expressing cancer with anti-icos antibodies
JP2023574355A JP2024520638A (ja) 2021-06-04 2022-06-06 抗ｉｃｏｓ抗体によるｐｄ－ｌ１陰性または低発現がんの処置
CN202280040129.8A CN117580861A (zh) 2021-06-04 2022-06-06 用抗icos抗体治疗pd-l1阴性或低表达癌症
US18/510,228 US20240190964A1 (en) 2021-06-04 2023-11-15 Treatment of pd-l1 negative or low expressing cancer with anti-icos antibodies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2107994.2A GB202107994D0 (en) 2021-06-04 2021-06-04 Treatment of cancer

Publications (1)

Publication Number Publication Date
GB202107994D0 true GB202107994D0 (en) 2021-07-21

Family

ID=76838824

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2107994.2A Ceased GB202107994D0 (en) 2021-06-04 2021-06-04 Treatment of cancer

Country Status (11)

Country Link
US (1) US20240190964A1 (https=)
EP (1) EP4347648A1 (https=)
JP (1) JP2024520638A (https=)
KR (1) KR20240017054A (https=)
CN (1) CN117580861A (https=)
AU (1) AU2022284342A1 (https=)
CA (1) CA3221115A1 (https=)
GB (1) GB202107994D0 (https=)
IL (1) IL308998A (https=)
TW (1) TW202313110A (https=)
WO (1) WO2022254227A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11858996B2 (en) * 2016-08-09 2024-01-02 Kymab Limited Anti-ICOS antibodies
CN120400071B (zh) * 2025-04-27 2025-10-21 天典(广东)生物科技有限公司 一种胰蛋白酶抑制剂降解酶突变体及其应用

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