GB201614834D0 - Treatment of dementia - Google Patents

Treatment of dementia

Info

Publication number
GB201614834D0
GB201614834D0 GBGB1614834.8A GB201614834A GB201614834D0 GB 201614834 D0 GB201614834 D0 GB 201614834D0 GB 201614834 A GB201614834 A GB 201614834A GB 201614834 D0 GB201614834 D0 GB 201614834D0
Authority
GB
United Kingdom
Prior art keywords
dementia
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1614834.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wista Laboratories Ltd
Original Assignee
Wista Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wista Laboratories Ltd filed Critical Wista Laboratories Ltd
Priority to GBGB1614834.8A priority Critical patent/GB201614834D0/en
Publication of GB201614834D0 publication Critical patent/GB201614834D0/en
Priority to SI201730630T priority patent/SI3506904T1/sl
Priority to PL17761842T priority patent/PL3506904T3/pl
Priority to JP2019511720A priority patent/JP7066679B2/ja
Priority to CA3034625A priority patent/CA3034625C/en
Priority to KR1020197009175A priority patent/KR102559354B1/ko
Priority to MYPI2019001119A priority patent/MY187564A/en
Priority to PT177618428T priority patent/PT3506904T/pt
Priority to US16/329,611 priority patent/US10842796B2/en
Priority to ES17761842T priority patent/ES2847929T3/es
Priority to AU2017318333A priority patent/AU2017318333B2/en
Priority to SG11201901125TA priority patent/SG11201901125TA/en
Priority to HRP20210162TT priority patent/HRP20210162T1/hr
Priority to PCT/EP2017/071437 priority patent/WO2018041739A1/en
Priority to MX2019002429A priority patent/MX384442B/es
Priority to CN201780067154.4A priority patent/CN109890391B/zh
Priority to EP17761842.8A priority patent/EP3506904B1/en
Priority to DK17761842.8T priority patent/DK3506904T3/da
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Valve Device For Special Equipments (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
GBGB1614834.8A 2016-09-01 2016-09-01 Treatment of dementia Ceased GB201614834D0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
GBGB1614834.8A GB201614834D0 (en) 2016-09-01 2016-09-01 Treatment of dementia
DK17761842.8T DK3506904T3 (da) 2016-09-01 2017-08-25 Behandling af demens
US16/329,611 US10842796B2 (en) 2016-09-01 2017-08-25 Treatment of dementia
AU2017318333A AU2017318333B2 (en) 2016-09-01 2017-08-25 Treatment of dementia
JP2019511720A JP7066679B2 (ja) 2016-09-01 2017-08-25 認知症の処置
CA3034625A CA3034625C (en) 2016-09-01 2017-08-25 Treatment of dementia
KR1020197009175A KR102559354B1 (ko) 2016-09-01 2017-08-25 치매 치료
MYPI2019001119A MY187564A (en) 2016-09-01 2017-08-25 Treatment of dementia
PT177618428T PT3506904T (pt) 2016-09-01 2017-08-25 Tratamento de demência
SI201730630T SI3506904T1 (sl) 2016-09-01 2017-08-25 Zdravljenje demence
ES17761842T ES2847929T3 (es) 2016-09-01 2017-08-25 Tratamiento de la demencia
PL17761842T PL3506904T3 (pl) 2016-09-01 2017-08-25 Leczenie otępienia
SG11201901125TA SG11201901125TA (en) 2016-09-01 2017-08-25 Treatment of dementia
HRP20210162TT HRP20210162T1 (hr) 2016-09-01 2017-08-25 Liječenje demencije
PCT/EP2017/071437 WO2018041739A1 (en) 2016-09-01 2017-08-25 Treatment of dementia
MX2019002429A MX384442B (es) 2016-09-01 2017-08-25 Tratamiento de la demencia.
CN201780067154.4A CN109890391B (zh) 2016-09-01 2017-08-25 痴呆症的治疗
EP17761842.8A EP3506904B1 (en) 2016-09-01 2017-08-25 Treatment of dementia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1614834.8A GB201614834D0 (en) 2016-09-01 2016-09-01 Treatment of dementia

Publications (1)

Publication Number Publication Date
GB201614834D0 true GB201614834D0 (en) 2016-10-19

Family

ID=57139937

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1614834.8A Ceased GB201614834D0 (en) 2016-09-01 2016-09-01 Treatment of dementia

Country Status (17)

Country Link
US (1) US10842796B2 (enExample)
EP (1) EP3506904B1 (enExample)
JP (1) JP7066679B2 (enExample)
KR (1) KR102559354B1 (enExample)
CN (1) CN109890391B (enExample)
AU (1) AU2017318333B2 (enExample)
DK (1) DK3506904T3 (enExample)
ES (1) ES2847929T3 (enExample)
GB (1) GB201614834D0 (enExample)
HR (1) HRP20210162T1 (enExample)
MX (1) MX384442B (enExample)
MY (1) MY187564A (enExample)
PL (1) PL3506904T3 (enExample)
PT (1) PT3506904T (enExample)
SG (1) SG11201901125TA (enExample)
SI (1) SI3506904T1 (enExample)
WO (1) WO2018041739A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104606199B (zh) 2006-03-29 2022-09-13 维斯塔实验室有限公司 3,7-二氨基-10h-吩噻嗪化合物盐及其用途
CN101511803B (zh) 2006-07-11 2012-10-31 维斯塔实验室有限公司 二氨基吩噻嗪*化合物的合成和/或纯化方法
PT3487505T (pt) 2016-07-25 2023-06-07 Wista Lab Ltd Administração e dosagem de diaminofenotiazinas
JP7465861B2 (ja) * 2018-07-26 2024-04-11 ウィスタ ラボラトリーズ リミテッド 集団におけるジアミノフェノチアジンの最適化投与
WO2020048593A1 (en) 2018-09-05 2020-03-12 Wista Laboratories Ltd. Network methods for neurodegenerative diseases
GB201909493D0 (en) 2019-07-01 2019-08-14 Wista Lab Ltd Therapeutic interactions
GB201909454D0 (en) * 2019-07-01 2019-08-14 Wista Lab Ltd Enhancers
GB201909506D0 (en) 2019-07-02 2019-08-14 Wista Lab Ltd Synaptopathies
GB202006659D0 (en) * 2020-05-05 2020-06-17 Wista Lab Ltd Therapeutic treatments
EP4146225B1 (en) * 2020-05-05 2024-10-09 WisTa Laboratories Ltd. Methylthioninium compounds for use in the treatment of hypoxemia
CA3257856A1 (en) 2022-05-31 2023-12-07 Wista Laboratories Ltd. TREATMENT OF NEURODEGENERATIVE DISORDERS USING COMPOUNDS CONTAINING METHYLTHIONINIUM (MT)
US20240115579A1 (en) * 2022-09-22 2024-04-11 Galenicum Health S.L.U. Pharmaceutical compositions and manufacturing methods thereof
EP4342451A1 (en) * 2022-09-22 2024-03-27 Galenicum Health SLU Pharmaceutical compositions and manufacturing methods thereof
EP4651874A2 (en) * 2023-02-21 2025-11-26 Prosetta Biosciences, Inc. Phenothiazinyl compounds and uses

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506197D0 (en) 1995-03-27 1995-05-17 Hoffmann La Roche Inhibition of tau-tau association.
GB0101049D0 (en) 2001-01-15 2001-02-28 Univ Aberdeen Materials and methods relating to protein aggregation in neurodegenerative disease
EP1509232B1 (en) 2002-05-31 2008-11-19 H. Lundbeck A/S A combination of an nmda-antagonist and acetylcholine esterase inhibitors for the treatment of alzheimer's disease
ES2409683T3 (es) 2004-09-23 2013-06-27 Wista Laboratories Ltd. Procedimientos de síntesis química y purificación de compuestos de diaminofenotiazinio que incluyen cloruro de metiltioninio (CMT)
CN104606199B (zh) 2006-03-29 2022-09-13 维斯塔实验室有限公司 3,7-二氨基-10h-吩噻嗪化合物盐及其用途
DK2001556T3 (da) * 2006-03-29 2014-11-10 Wista Lab Ltd Thioninium-forbindelser og anvendelse deraf
FR2899107B1 (fr) * 2006-03-30 2008-06-13 Neurokin Entpr Unipersonnelle Utilisation de la (s)-roscovitine pour la fabrication d'un medicament
CN101511803B (zh) 2006-07-11 2012-10-31 维斯塔实验室有限公司 二氨基吩噻嗪*化合物的合成和/或纯化方法
FR2903696B1 (fr) 2006-07-12 2011-02-11 Provence Technologies Procede de purification de composes diaminophenothiazium
US9034890B2 (en) * 2006-11-15 2015-05-19 Steven A. Rich Combined acetylcholinesterase inhibitor and quaternary ammonium antimuscarinic therapy to alter progression of cognitive diseases
PL2167095T3 (pl) 2007-06-19 2019-11-29 Wista Lab Ltd Związki fenotiazynowe do leczenia łagodnych zaburzeń poznawczych
DK2205245T3 (en) 2007-10-03 2015-09-28 Wista Lab Ltd Therapeutic use of diaminophenothiaziner
EP3378856B1 (en) 2009-09-24 2020-12-02 WisTa Laboratories Ltd. Crystalline methylthioninium chloride hydrates
BR112012006626B8 (pt) 2009-09-24 2021-05-25 Wista Lab Ltd processo para a preparação da forma a pentahidratada e método da secagem da forma a pentahidratada de mtc
CA2827027C (en) 2011-02-11 2019-06-04 Wista Laboratories Ltd. Phenothiazine diaminium salts and their use
CN102936244B (zh) * 2012-12-04 2015-02-04 合肥工业大学 一种他克林-吩噻嗪异二联体类化合物及其制备方法

Also Published As

Publication number Publication date
AU2017318333A1 (en) 2019-04-18
HRP20210162T1 (hr) 2021-03-19
EP3506904B1 (en) 2020-12-09
US20190192530A1 (en) 2019-06-27
SG11201901125TA (en) 2019-03-28
KR20190045273A (ko) 2019-05-02
DK3506904T3 (da) 2021-01-04
SI3506904T1 (sl) 2021-03-31
JP7066679B2 (ja) 2022-05-13
JP2019526571A (ja) 2019-09-19
MX2019002429A (es) 2019-07-08
US10842796B2 (en) 2020-11-24
CN109890391B (zh) 2023-01-31
CN109890391A (zh) 2019-06-14
KR102559354B1 (ko) 2023-07-26
AU2017318333B2 (en) 2023-05-11
MX384442B (es) 2025-03-14
EP3506904A1 (en) 2019-07-10
PL3506904T3 (pl) 2021-07-26
ES2847929T3 (es) 2021-08-04
MY187564A (en) 2021-09-30
PT3506904T (pt) 2021-02-02
CA3034625A1 (en) 2018-03-08
WO2018041739A1 (en) 2018-03-08

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)