GB201614834D0 - Treatment of dementia - Google Patents

Treatment of dementia

Info

Publication number
GB201614834D0
GB201614834D0 GBGB1614834.8A GB201614834A GB201614834D0 GB 201614834 D0 GB201614834 D0 GB 201614834D0 GB 201614834 A GB201614834 A GB 201614834A GB 201614834 D0 GB201614834 D0 GB 201614834D0
Authority
GB
United Kingdom
Prior art keywords
dementia
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1614834.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wista Laboratories Ltd
Original Assignee
Wista Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wista Laboratories Ltd filed Critical Wista Laboratories Ltd
Priority to GBGB1614834.8A priority Critical patent/GB201614834D0/en
Publication of GB201614834D0 publication Critical patent/GB201614834D0/en
Priority to AU2017318333A priority patent/AU2017318333B2/en
Priority to CA3034625A priority patent/CA3034625A1/en
Priority to ES17761842T priority patent/ES2847929T3/es
Priority to JP2019511720A priority patent/JP7066679B2/ja
Priority to PL17761842T priority patent/PL3506904T3/pl
Priority to SI201730630T priority patent/SI3506904T1/sl
Priority to DK17761842.8T priority patent/DK3506904T3/da
Priority to CN201780067154.4A priority patent/CN109890391B/zh
Priority to MX2019002429A priority patent/MX384442B/es
Priority to PCT/EP2017/071437 priority patent/WO2018041739A1/en
Priority to MYPI2019001119A priority patent/MY187564A/en
Priority to KR1020197009175A priority patent/KR102559354B1/ko
Priority to HRP20210162TT priority patent/HRP20210162T1/hr
Priority to PT177618428T priority patent/PT3506904T/pt
Priority to US16/329,611 priority patent/US10842796B2/en
Priority to SG11201901125TA priority patent/SG11201901125TA/en
Priority to EP17761842.8A priority patent/EP3506904B1/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Valve Device For Special Equipments (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
GBGB1614834.8A 2016-09-01 2016-09-01 Treatment of dementia Ceased GB201614834D0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
GBGB1614834.8A GB201614834D0 (en) 2016-09-01 2016-09-01 Treatment of dementia
EP17761842.8A EP3506904B1 (en) 2016-09-01 2017-08-25 Treatment of dementia
CN201780067154.4A CN109890391B (zh) 2016-09-01 2017-08-25 痴呆症的治疗
PCT/EP2017/071437 WO2018041739A1 (en) 2016-09-01 2017-08-25 Treatment of dementia
ES17761842T ES2847929T3 (es) 2016-09-01 2017-08-25 Tratamiento de la demencia
JP2019511720A JP7066679B2 (ja) 2016-09-01 2017-08-25 認知症の処置
PL17761842T PL3506904T3 (pl) 2016-09-01 2017-08-25 Leczenie otępienia
SI201730630T SI3506904T1 (sl) 2016-09-01 2017-08-25 Zdravljenje demence
DK17761842.8T DK3506904T3 (da) 2016-09-01 2017-08-25 Behandling af demens
AU2017318333A AU2017318333B2 (en) 2016-09-01 2017-08-25 Treatment of dementia
MX2019002429A MX384442B (es) 2016-09-01 2017-08-25 Tratamiento de la demencia.
CA3034625A CA3034625A1 (en) 2016-09-01 2017-08-25 Treatment of dementia
MYPI2019001119A MY187564A (en) 2016-09-01 2017-08-25 Treatment of dementia
KR1020197009175A KR102559354B1 (ko) 2016-09-01 2017-08-25 치매 치료
HRP20210162TT HRP20210162T1 (hr) 2016-09-01 2017-08-25 Liječenje demencije
PT177618428T PT3506904T (pt) 2016-09-01 2017-08-25 Tratamento de demência
US16/329,611 US10842796B2 (en) 2016-09-01 2017-08-25 Treatment of dementia
SG11201901125TA SG11201901125TA (en) 2016-09-01 2017-08-25 Treatment of dementia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1614834.8A GB201614834D0 (en) 2016-09-01 2016-09-01 Treatment of dementia

Publications (1)

Publication Number Publication Date
GB201614834D0 true GB201614834D0 (en) 2016-10-19

Family

ID=57139937

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1614834.8A Ceased GB201614834D0 (en) 2016-09-01 2016-09-01 Treatment of dementia

Country Status (18)

Country Link
US (1) US10842796B2 (enExample)
EP (1) EP3506904B1 (enExample)
JP (1) JP7066679B2 (enExample)
KR (1) KR102559354B1 (enExample)
CN (1) CN109890391B (enExample)
AU (1) AU2017318333B2 (enExample)
CA (1) CA3034625A1 (enExample)
DK (1) DK3506904T3 (enExample)
ES (1) ES2847929T3 (enExample)
GB (1) GB201614834D0 (enExample)
HR (1) HRP20210162T1 (enExample)
MX (1) MX384442B (enExample)
MY (1) MY187564A (enExample)
PL (1) PL3506904T3 (enExample)
PT (1) PT3506904T (enExample)
SG (1) SG11201901125TA (enExample)
SI (1) SI3506904T1 (enExample)
WO (1) WO2018041739A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109384741B (zh) 2006-03-29 2023-01-06 维斯塔实验室有限公司 3,7-二氨基-10h-吩噻嗪化合物盐及其用途
HUE030621T2 (en) 2006-07-11 2017-05-29 Wista Lab Ltd Methods for the synthesis and / or purification of diaminophenothiazinium compounds
AU2017301966B2 (en) 2016-07-25 2022-09-22 TauRx Therapeutics Management Ltd Administration and dosage of diaminophenothiazines
EP3826639B1 (en) 2018-07-26 2024-08-21 WisTa Laboratories Ltd. Optimised dosage of diaminophenothiazines in populations
WO2020048593A1 (en) 2018-09-05 2020-03-12 Wista Laboratories Ltd. Network methods for neurodegenerative diseases
GB201909493D0 (en) * 2019-07-01 2019-08-14 Wista Lab Ltd Therapeutic interactions
GB201909454D0 (en) * 2019-07-01 2019-08-14 Wista Lab Ltd Enhancers
GB201909506D0 (en) 2019-07-02 2019-08-14 Wista Lab Ltd Synaptopathies
JP2023524146A (ja) * 2020-05-05 2023-06-08 ウィスタ ラボラトリーズ リミテッド 低酸素血症の治療に使用されるメチルチオニニウム化合物
GB202006659D0 (en) * 2020-05-05 2020-06-17 Wista Lab Ltd Therapeutic treatments
EP4531863A1 (en) 2022-05-31 2025-04-09 WisTa Laboratories Ltd. Treatment of neurodegenerative disorders utilising methylthioninium (mt)-containing compounds
US20240115579A1 (en) * 2022-09-22 2024-04-11 Galenicum Health S.L.U. Pharmaceutical compositions and manufacturing methods thereof
EP4342451A1 (en) * 2022-09-22 2024-03-27 Galenicum Health SLU Pharmaceutical compositions and manufacturing methods thereof
US20240300940A1 (en) * 2023-02-21 2024-09-12 Prosetta Biosciences, Inc. Phenothiazinyl Compounds and Uses

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506197D0 (en) 1995-03-27 1995-05-17 Hoffmann La Roche Inhibition of tau-tau association.
GB0101049D0 (en) 2001-01-15 2001-02-28 Univ Aberdeen Materials and methods relating to protein aggregation in neurodegenerative disease
DE60324788D1 (de) * 2002-05-31 2009-01-02 Lundbeck & Co As H Kombination aus einem nmda-antagonist und acetylcholinesterase-hemmern zur behandlung der alzheimer-krankheit
PT1799662E (pt) 2004-09-23 2013-07-09 Wista Lab Ltd Métodos de síntese química e purificação de compostos de diaminofenotiazínio incluindo cloreto de metiltionínio (mtc)
EP2853293B1 (en) * 2006-03-29 2017-11-22 WisTa Laboratories Ltd. Thioninium compounds and their use
CN109384741B (zh) 2006-03-29 2023-01-06 维斯塔实验室有限公司 3,7-二氨基-10h-吩噻嗪化合物盐及其用途
FR2899107B1 (fr) * 2006-03-30 2008-06-13 Neurokin Entpr Unipersonnelle Utilisation de la (s)-roscovitine pour la fabrication d'un medicament
HUE030621T2 (en) 2006-07-11 2017-05-29 Wista Lab Ltd Methods for the synthesis and / or purification of diaminophenothiazinium compounds
FR2903696B1 (fr) 2006-07-12 2011-02-11 Provence Technologies Procede de purification de composes diaminophenothiazium
US9034890B2 (en) * 2006-11-15 2015-05-19 Steven A. Rich Combined acetylcholinesterase inhibitor and quaternary ammonium antimuscarinic therapy to alter progression of cognitive diseases
CN101820884B (zh) * 2007-06-19 2013-08-28 维斯塔实验室有限公司 用于治疗轻度认知缺损的吩噻嗪化合物
SI2205245T1 (sl) 2007-10-03 2015-10-30 Wista Laboratories Ltd. Terapevtska uporaba diaminofenotiazinov
ES2689029T3 (es) 2009-09-24 2018-11-08 Wista Laboratories Ltd. Hidratos de cloruro de metiltioninio cristalinos - Parte 2
PL2480540T3 (pl) 2009-09-24 2018-05-30 Wista Laboratories Ltd. Pentahydrat chlorku metylotioninowego, jego wytwarzanie i zastosowanie farmaceutyczne
EA025033B1 (ru) * 2011-02-11 2016-11-30 Уиста Лэборэтэриз Лтд. Диаминиевые соли фенотиазина и их применение
CN102936244B (zh) * 2012-12-04 2015-02-04 合肥工业大学 一种他克林-吩噻嗪异二联体类化合物及其制备方法

Also Published As

Publication number Publication date
MX384442B (es) 2025-03-14
DK3506904T3 (da) 2021-01-04
CA3034625A1 (en) 2018-03-08
EP3506904A1 (en) 2019-07-10
CN109890391A (zh) 2019-06-14
SG11201901125TA (en) 2019-03-28
MX2019002429A (es) 2019-07-08
US20190192530A1 (en) 2019-06-27
AU2017318333A1 (en) 2019-04-18
ES2847929T3 (es) 2021-08-04
CN109890391B (zh) 2023-01-31
PL3506904T3 (pl) 2021-07-26
EP3506904B1 (en) 2020-12-09
JP2019526571A (ja) 2019-09-19
SI3506904T1 (sl) 2021-03-31
KR20190045273A (ko) 2019-05-02
KR102559354B1 (ko) 2023-07-26
HRP20210162T1 (hr) 2021-03-19
WO2018041739A1 (en) 2018-03-08
AU2017318333B2 (en) 2023-05-11
US10842796B2 (en) 2020-11-24
MY187564A (en) 2021-09-30
PT3506904T (pt) 2021-02-02
JP7066679B2 (ja) 2022-05-13

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)