GB201520499D0 - Compounds - Google Patents
CompoundsInfo
- Publication number
- GB201520499D0 GB201520499D0 GBGB1520499.3A GB201520499A GB201520499D0 GB 201520499 D0 GB201520499 D0 GB 201520499D0 GB 201520499 A GB201520499 A GB 201520499A GB 201520499 D0 GB201520499 D0 GB 201520499D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1520499.3A GB201520499D0 (en) | 2015-11-20 | 2015-11-20 | Compounds |
| HK18112781.8A HK1253576B (en) | 2015-11-20 | 2016-11-16 | Pyrropyrimidine compounds as mnks inhibitors |
| EP20204385.7A EP3792264B1 (en) | 2015-11-20 | 2016-11-16 | Pyrropyrimidine compounds as mnks inhibitors |
| EP16801015.5A EP3377494B1 (en) | 2015-11-20 | 2016-11-16 | Pyrropyrimidine compounds as mnks inhibitors |
| AU2016355103A AU2016355103B2 (en) | 2015-11-20 | 2016-11-16 | Pyrropyrimidine compounds as MNKs inhibitors |
| ES20204385T ES2972862T3 (es) | 2015-11-20 | 2016-11-16 | Compuestos de pirropirimidina como inhibidores de MNK |
| CA3003554A CA3003554C (en) | 2015-11-20 | 2016-11-16 | Pyrropyrimidine compounds as mnks inhibitors |
| US15/776,574 US10604524B2 (en) | 2015-11-20 | 2016-11-16 | Pyrropyrimidine compounds as MNKs inhibitors |
| CN201680067666.6A CN108368114B (zh) | 2015-11-20 | 2016-11-16 | 作为mnk抑制剂的吡咯并嘧啶化合物 |
| JP2018525743A JP6946290B2 (ja) | 2015-11-20 | 2016-11-16 | Ｍｎｋ阻害剤としてのピロロピリミジン化合物 |
| PCT/GB2016/053579 WO2017085483A1 (en) | 2015-11-20 | 2016-11-16 | Pyrropyrimidine compounds as mnks inhibitors |
| ES16801015T ES2872775T3 (es) | 2015-11-20 | 2016-11-16 | Compuestos de pirropirimidina como inhibidores de MNK |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1520499.3A GB201520499D0 (en) | 2015-11-20 | 2015-11-20 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201520499D0 true GB201520499D0 (en) | 2016-01-06 |
Family
ID=55133105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1520499.3A Ceased GB201520499D0 (en) | 2015-11-20 | 2015-11-20 | Compounds |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10604524B2 (enExample) |
| EP (2) | EP3377494B1 (enExample) |
| JP (1) | JP6946290B2 (enExample) |
| CN (1) | CN108368114B (enExample) |
| AU (1) | AU2016355103B2 (enExample) |
| CA (1) | CA3003554C (enExample) |
| ES (2) | ES2972862T3 (enExample) |
| GB (1) | GB201520499D0 (enExample) |
| WO (1) | WO2017085483A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI713455B (zh) | 2014-06-25 | 2020-12-21 | 美商伊凡克特治療公司 | ＭｎＫ抑制劑及其相關方法 |
| ES2969988T3 (es) | 2017-02-14 | 2024-05-23 | Effector Therapeutics Inc | Inhibidores de Mnk sustituidos con piperidina y métodos relacionados con los mismos |
| CN109020957B (zh) * | 2017-06-12 | 2023-01-13 | 南京天印健华医药科技有限公司 | 作为mnk抑制剂的杂环化合物 |
| WO2020086713A1 (en) | 2018-10-24 | 2020-04-30 | Effector Therapeutics, Inc. | Crystalline forms of mnk inhibitors |
| CN110903286B (zh) * | 2019-12-16 | 2021-09-24 | 沈阳药科大学 | 4,6-双取代吡啶[3,2-d]嘧啶类化合物及其制备和应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
| SK72996A3 (en) * | 1995-06-07 | 1997-04-09 | Pfizer | Heterocyclic ring-fused pyrimidine derivatives and pharmaceutical compositions on their base |
| KR20000057228A (ko) * | 1996-11-27 | 2000-09-15 | 디. 제이. 우드, 스피겔 알렌 제이 | 축합된 비사이클릭 피리미딘 유도체 |
| JP2004509059A (ja) | 1999-06-03 | 2004-03-25 | アボット・ラボラトリーズ | 細胞接着抑制性抗炎症化合物 |
| US20050165029A1 (en) | 2004-01-13 | 2005-07-28 | Ambit Biosciences Corporation | Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases |
| EP1773826A4 (en) | 2004-07-02 | 2009-06-03 | Exelixis Inc | MODULATORS OF C-MET AND THEIR METHOD OF USE |
| TW200730527A (en) * | 2005-12-02 | 2007-08-16 | Takeda Pharmaceuticals Co | Fused heterocyclic compound |
| US8633201B2 (en) * | 2006-04-07 | 2014-01-21 | Boehringer Ingelheim International Gmbh | Thienopyrimidines having Mnk1/Mnk2 inhibiting activity for pharmaceutical compositions |
| EP1889847A1 (en) * | 2006-07-10 | 2008-02-20 | DeveloGen Aktiengesellschaft | Pyrrolopyrimidines for pharmaceutical compositions |
| EP2219649A2 (en) * | 2007-11-22 | 2010-08-25 | Boehringer Ingelheim International Gmbh | Use of mnk inhibitors for the treatment of alzheimer's disease |
| JP5626748B2 (ja) * | 2008-07-02 | 2014-11-19 | キッコーマン株式会社 | ペプチド含有調味料 |
| JP5575274B2 (ja) * | 2010-02-26 | 2014-08-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医薬組成物のためのｍｎｋｌ／ｍｎｋ２阻害活性を有する４−［シクロアルキルオキシ（ヘテロ）アリールアミノ］チエノ「２，３−ｄ］ピリミジン |
| EP2539343B1 (en) | 2010-02-26 | 2015-12-30 | Evotec International GmbH | Thienopyrimidines containing a substituted alkyl group for pharmaceutical compositions |
| ES2653419T3 (es) | 2013-02-01 | 2018-02-07 | Bayer Pharma Aktiengesellschaft | Pirazolopirimidinilamino-indazoles sustituidos |
| US9675612B2 (en) | 2013-03-06 | 2017-06-13 | Bayer Pharma Aktiengesellschaft | Substituted thiazolopyrimidines |
| CN104744446B (zh) * | 2013-12-30 | 2019-06-25 | 广东东阳光药业有限公司 | 杂芳化合物及其在药物中的应用 |
-
2015
- 2015-11-20 GB GBGB1520499.3A patent/GB201520499D0/en not_active Ceased
-
2016
- 2016-11-16 ES ES20204385T patent/ES2972862T3/es active Active
- 2016-11-16 EP EP16801015.5A patent/EP3377494B1/en active Active
- 2016-11-16 CA CA3003554A patent/CA3003554C/en active Active
- 2016-11-16 AU AU2016355103A patent/AU2016355103B2/en not_active Ceased
- 2016-11-16 CN CN201680067666.6A patent/CN108368114B/zh not_active Expired - Fee Related
- 2016-11-16 JP JP2018525743A patent/JP6946290B2/ja not_active Expired - Fee Related
- 2016-11-16 WO PCT/GB2016/053579 patent/WO2017085483A1/en not_active Ceased
- 2016-11-16 ES ES16801015T patent/ES2872775T3/es active Active
- 2016-11-16 EP EP20204385.7A patent/EP3792264B1/en active Active
- 2016-11-16 US US15/776,574 patent/US10604524B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018534316A (ja) | 2018-11-22 |
| JP6946290B2 (ja) | 2021-10-06 |
| EP3792264A1 (en) | 2021-03-17 |
| EP3792264B1 (en) | 2024-01-03 |
| CA3003554A1 (en) | 2017-05-26 |
| CN108368114B (zh) | 2023-10-24 |
| EP3377494A1 (en) | 2018-09-26 |
| CA3003554C (en) | 2023-08-29 |
| AU2016355103B2 (en) | 2021-07-08 |
| AU2016355103A1 (en) | 2018-05-31 |
| HK1253576A1 (en) | 2019-06-21 |
| WO2017085483A1 (en) | 2017-05-26 |
| ES2972862T3 (es) | 2024-06-17 |
| EP3377494B1 (en) | 2021-03-03 |
| US10604524B2 (en) | 2020-03-31 |
| CN108368114A (zh) | 2018-08-03 |
| US20180346469A1 (en) | 2018-12-06 |
| ES2872775T3 (es) | 2021-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |