GB201518674D0 - Method for detecting nuleosomes containing histone modifications and variants - Google Patents
Method for detecting nuleosomes containing histone modifications and variantsInfo
- Publication number
- GB201518674D0 GB201518674D0 GBGB1518674.5A GB201518674A GB201518674D0 GB 201518674 D0 GB201518674 D0 GB 201518674D0 GB 201518674 A GB201518674 A GB 201518674A GB 201518674 D0 GB201518674 D0 GB 201518674D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- nuleosomes
- variants
- detecting
- histone modifications
- containing histone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1518674.5A GB201518674D0 (en) | 2015-10-21 | 2015-10-21 | Method for detecting nuleosomes containing histone modifications and variants |
| EP16787535.0A EP3365681B1 (en) | 2015-10-21 | 2016-10-21 | Method for detecting nucleosomes containing histone modifications and variants |
| CN201680074822.1A CN108496083A (zh) | 2015-10-21 | 2016-10-21 | 用于检测包含组蛋白修饰和变体的核小体的方法 |
| JP2018520476A JP6925328B2 (ja) | 2015-10-21 | 2016-10-21 | ヒストン修飾及びバリアントを含むヌクレオソームを検出するための方法 |
| US15/768,981 US10768182B2 (en) | 2015-10-21 | 2016-10-21 | Method for detecting nucleosomes containing histone modifications and variants |
| PCT/GB2016/053288 WO2017068359A1 (en) | 2015-10-21 | 2016-10-21 | Method for detecting nucleosomes containing histone modifications and variants |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1518674.5A GB201518674D0 (en) | 2015-10-21 | 2015-10-21 | Method for detecting nuleosomes containing histone modifications and variants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201518674D0 true GB201518674D0 (en) | 2015-12-02 |
Family
ID=55131420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1518674.5A Ceased GB201518674D0 (en) | 2015-10-21 | 2015-10-21 | Method for detecting nuleosomes containing histone modifications and variants |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10768182B2 (enExample) |
| EP (1) | EP3365681B1 (enExample) |
| JP (1) | JP6925328B2 (enExample) |
| CN (1) | CN108496083A (enExample) |
| GB (1) | GB201518674D0 (enExample) |
| WO (1) | WO2017068359A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016128383A1 (en) | 2015-02-10 | 2016-08-18 | B.R.A.H.M.S Gmbh | Free histone proteins as biomarkers |
| PL4070111T3 (pl) * | 2019-12-02 | 2025-02-03 | Belgian Volition Srl | Zastosowanie wolnych pozakomórkowych nukleosomsów jako biomarkerów |
| IL300080A (en) | 2020-08-18 | 2023-03-01 | Onchilles Pharma Inc | Processed porcine pancreatic elastase proteins |
| GB202108185D0 (en) | 2021-06-08 | 2021-07-21 | Belgian Volition Sprl | Standardisation of nucleosome assays using biologically derived calibrants |
| CN113480646B (zh) * | 2021-07-01 | 2022-03-15 | 中国科学院生物物理研究所 | 特异性结合h1.4移码突变蛋白的单克隆抗体制备及其应用 |
| GB202117799D0 (en) | 2021-12-09 | 2022-01-26 | Belgian Volition Srl | Method for the detection of blood cancer |
| US20250197944A1 (en) | 2022-03-11 | 2025-06-19 | Belgian Volition Srl | Differential diagnosis method |
| GB202205212D0 (en) | 2022-04-08 | 2022-05-25 | Belgian Volition Sprl | Method for transplant organ health assessment |
| WO2024133225A1 (en) | 2022-12-19 | 2024-06-27 | Belgian Volition Srl | Calibration |
| EP4695610A1 (en) | 2023-04-14 | 2026-02-18 | Belgian Volition SRL | Diagnosis method using cell free nucleosome levels |
| WO2024223947A1 (en) | 2023-04-28 | 2024-10-31 | Belgian Volition Srl | Use of cell free nucleosomes as biomarkers of carcinomas |
| GB202307768D0 (en) | 2023-05-24 | 2023-07-05 | Belgian Volition Srl | Use of cell free nucleosomes as biomarkers |
| GB202310137D0 (en) | 2023-07-03 | 2023-08-16 | Belgian Volition Srl | Method for the detection of cancer |
| WO2025061853A1 (en) | 2023-09-19 | 2025-03-27 | Belgian Volition Srl | Lateral flow test device |
| WO2025094148A1 (en) * | 2023-11-03 | 2025-05-08 | Onchilles Pharma, Inc. | Histone h1 levels as biomarkers for cancer therapy |
| CN117904196B (zh) * | 2024-01-05 | 2024-07-12 | 安徽大学 | 一种非小细胞肺癌组蛋白h1.4赖氨酸乙酰化点突变细胞模型的构建及其应用 |
| WO2025181348A1 (en) | 2024-03-01 | 2025-09-04 | Belgian Volition Srl | Method for determining the origin of circulating dna |
| WO2025253002A1 (en) | 2024-06-07 | 2025-12-11 | Belgian Volition Srl | Sample collection for liquid biopsy |
| WO2026052765A1 (en) | 2024-09-05 | 2026-03-12 | Belgian Volition Srl | Method using nucleosome levels |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0319376D0 (en) * | 2003-08-18 | 2003-09-17 | Chroma Therapeutics Ltd | Histone modification detection |
| US20130078642A1 (en) | 2010-06-03 | 2013-03-28 | Porto Conte Richerche S.R.L. | Biomarkers for lung neuroendocrine tumors |
| GB201115095D0 (en) | 2011-09-01 | 2011-10-19 | Singapore Volition Pte Ltd | Method for detecting nucleosomes containing nucleotides |
| GB201115098D0 (en) * | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes containing histone variants |
| AU2012349855B2 (en) * | 2011-12-07 | 2017-12-07 | Belgian Volition Sprl | Method for detecting nucleosome adducts |
| EP2820129A1 (en) * | 2012-03-02 | 2015-01-07 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| GB201303575D0 (en) | 2013-02-28 | 2013-04-10 | Singapore Volition Pte Ltd | Method for detecting histone modifications in nucleosomes |
-
2015
- 2015-10-21 GB GBGB1518674.5A patent/GB201518674D0/en not_active Ceased
-
2016
- 2016-10-21 CN CN201680074822.1A patent/CN108496083A/zh active Pending
- 2016-10-21 WO PCT/GB2016/053288 patent/WO2017068359A1/en not_active Ceased
- 2016-10-21 EP EP16787535.0A patent/EP3365681B1/en active Active
- 2016-10-21 US US15/768,981 patent/US10768182B2/en active Active
- 2016-10-21 JP JP2018520476A patent/JP6925328B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3365681A1 (en) | 2018-08-29 |
| US20190064183A1 (en) | 2019-02-28 |
| JP6925328B2 (ja) | 2021-08-25 |
| US10768182B2 (en) | 2020-09-08 |
| JP2018536849A (ja) | 2018-12-13 |
| WO2017068359A1 (en) | 2017-04-27 |
| CN108496083A (zh) | 2018-09-04 |
| EP3365681B1 (en) | 2023-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |