GB201509782D0 - Methods and products for fusion protein synthesis - Google Patents
Methods and products for fusion protein synthesisInfo
- Publication number
- GB201509782D0 GB201509782D0 GBGB1509782.7A GB201509782A GB201509782D0 GB 201509782 D0 GB201509782 D0 GB 201509782D0 GB 201509782 A GB201509782 A GB 201509782A GB 201509782 D0 GB201509782 D0 GB 201509782D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- products
- methods
- fusion protein
- protein synthesis
- synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Pulmonology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1509782.7A GB201509782D0 (en) | 2015-06-05 | 2015-06-05 | Methods and products for fusion protein synthesis |
| EP16728359.7A EP3303374B1 (en) | 2015-06-05 | 2016-06-03 | Methods and products for fusion protein synthesis |
| JP2017563189A JP6883529B2 (ja) | 2015-06-05 | 2016-06-03 | 融合タンパク質を合成するための方法および製品 |
| US15/578,486 US10526379B2 (en) | 2015-06-05 | 2016-06-03 | Methods and products for fusion protein synthesis |
| DK16728359.7T DK3303374T3 (da) | 2015-06-05 | 2016-06-03 | FREMGANGSMÅDER OG PRODUKTER til FUSIONSPROTEINSYNTESE |
| PCT/GB2016/051640 WO2016193746A1 (en) | 2015-06-05 | 2016-06-03 | Methods and products for fusion protein synthesis |
| KR1020187000488A KR102818627B1 (ko) | 2015-06-05 | 2016-06-03 | 융합 단백질 합성용 방법 및 생성물 |
| CA2987821A CA2987821C (en) | 2015-06-05 | 2016-06-03 | Methods and products for fusion protein synthesis |
| CN202211548024.1A CN116199733A (zh) | 2015-06-05 | 2016-06-03 | 融合蛋白合成的方法和产品 |
| AU2016272543A AU2016272543B2 (en) | 2015-06-05 | 2016-06-03 | Methods and products for fusion protein synthesis |
| ES16728359T ES2880336T3 (es) | 2015-06-05 | 2016-06-03 | Métodos y productos para la síntesis de proteínas de fusión |
| CN201680037511.8A CN108026148B (zh) | 2015-06-05 | 2016-06-03 | 融合蛋白合成的方法和产品 |
| BR112017026042-5A BR112017026042B1 (pt) | 2015-06-05 | 2016-06-03 | Proteína de fusão e seu método de produção, ligante de peptídeo, par de ligantes de peptídeo e uso dos mesmos, polipeptídeo recombinante ou sintético, molécula de ácido nucleico, vetor, célula hospedeira recombinante e kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1509782.7A GB201509782D0 (en) | 2015-06-05 | 2015-06-05 | Methods and products for fusion protein synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201509782D0 true GB201509782D0 (en) | 2015-07-22 |
Family
ID=53785013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1509782.7A Ceased GB201509782D0 (en) | 2015-06-05 | 2015-06-05 | Methods and products for fusion protein synthesis |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10526379B2 (https=) |
| EP (1) | EP3303374B1 (https=) |
| JP (1) | JP6883529B2 (https=) |
| KR (1) | KR102818627B1 (https=) |
| CN (2) | CN116199733A (https=) |
| AU (1) | AU2016272543B2 (https=) |
| DK (1) | DK3303374T3 (https=) |
| ES (1) | ES2880336T3 (https=) |
| GB (1) | GB201509782D0 (https=) |
| WO (1) | WO2016193746A1 (https=) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016112921A1 (en) | 2015-01-15 | 2016-07-21 | University Of Copenhagen | Virus-like particle with efficient epitope display |
| GB201509782D0 (en) * | 2015-06-05 | 2015-07-22 | Isis Innovation | Methods and products for fusion protein synthesis |
| EP3368068B1 (en) | 2015-10-30 | 2020-11-18 | University of Copenhagen | Virus like particle with efficient epitope display |
| US11119054B2 (en) | 2017-03-16 | 2021-09-14 | The Penn State Research Foundation | Versatile display scaffolds for proteins |
| GB201705750D0 (en) * | 2017-04-10 | 2017-05-24 | Univ Oxford Innovation Ltd | Peptide ligase and use therof |
| GB201706430D0 (en) * | 2017-04-24 | 2017-06-07 | Univ Oxford Innovation Ltd | Proteins and peptide tags with enhanced rate of spontaneous isopeptide bond formation and uses thereof |
| CN107299107A (zh) * | 2017-07-31 | 2017-10-27 | 北京大学 | 一种蛋白质层层组装功能材料的制备方法 |
| US11059868B2 (en) | 2017-10-25 | 2021-07-13 | Abera Bioscience Ab | Display of heterologous molecules on bacterial cells and membrane vesicles |
| EP3774926A1 (en) | 2018-04-05 | 2021-02-17 | Bio-Rad ABD Serotec GmbH | Display systems for proteins of interest |
| CN112638411B (zh) | 2018-05-04 | 2025-03-04 | 斯拜生物技术有限公司 | 疫苗组合物 |
| WO2020041202A1 (en) * | 2018-08-20 | 2020-02-27 | The Regents Of The University Of California | Graphene oxide affinity sample grids for cryo-em |
| CN111073925B (zh) * | 2018-10-19 | 2022-04-26 | 北京大学 | 一种基于无序蛋白偶联酶的高效多肽-多肽偶联系统和方法 |
| GB201819850D0 (en) | 2018-12-05 | 2019-01-23 | Univ Oxford Innovation Ltd | Polypeptide and its use in affinity purification |
| GB201903479D0 (en) * | 2019-03-14 | 2019-05-01 | Univ Oxford Innovation Ltd | Polypeptide with enchanced rate of spontaneous isopeptide bond formation with it's peptide tag partner and uses thereof |
| JP2022526492A (ja) * | 2019-03-18 | 2022-05-25 | バイオ－ラッド エービーディー セロテック ゲーエムベーハー | 複数のｆｃアイソタイプ及びサブクラスに結合した抗原結合フラグメント |
| US20200299358A1 (en) * | 2019-03-18 | 2020-09-24 | Bio-Rad Abd Serotec Gmbh | Antigen binding proteins |
| EP3942079A1 (en) * | 2019-03-18 | 2022-01-26 | Bio-Rad ABD Serotec GmbH | Protection of spytag-containing periplasmic fusion proteins from protease tsp and ompt degradation |
| US12163164B2 (en) | 2019-07-15 | 2024-12-10 | Bio-Rad Laboratories, Inc. | Hybrid reverse transcriptases |
| NL2023863B1 (en) | 2019-09-20 | 2021-05-25 | Univ Griffith | Protein particles and uses thereof |
| CN112646800B (zh) * | 2019-10-11 | 2025-10-17 | 北京科技大学 | 制备固定化酶或固定化蛋白质的方法以及固定化酶或固定化蛋白质 |
| GB201915905D0 (en) | 2019-11-01 | 2019-12-18 | Spybiotech Ltd | Viruses with modified capsid proteins |
| EP3831843A1 (en) * | 2019-12-08 | 2021-06-09 | Royal College Of Surgeons In Ireland | A hemostatic agent and uses thereof |
| EP4135665A2 (en) * | 2020-04-13 | 2023-02-22 | Mantra Bio, Inc. | Modular binding proteins for extracellular vesicles and uses thereof |
| WO2021224451A1 (en) * | 2020-05-07 | 2021-11-11 | Adaptvac Aps | Peptide tags and binding partners |
| EP4176262B1 (en) * | 2020-07-02 | 2025-06-25 | King Abdullah University Of Science And Technology | Nanobody functionalized electrochemical transistors and methods of making and using thereof |
| WO2022076914A1 (en) | 2020-10-09 | 2022-04-14 | 10X Genomics, Inc. | Methods and compositions for profiling immune repertoire |
| US12298314B2 (en) | 2020-10-09 | 2025-05-13 | 10X Genomics, Inc. | Methods and compositions for analyzing target binding of molecules |
| GB202019817D0 (en) | 2020-12-15 | 2021-01-27 | Univ Oxford Innovation Ltd | Ligand-binding polypeptides and uses thereof |
| GB202104104D0 (en) * | 2021-03-24 | 2021-05-05 | Liliumx Ltd | Platform and method |
| GB202104999D0 (en) * | 2021-04-08 | 2021-05-26 | Univ Oxford Innovation Ltd | Polypeptides that interact with peptide tags at loops or termini and uses thereof |
| CN113621031B (zh) * | 2021-04-23 | 2023-05-05 | 中山大学 | 一种利用自发异肽键进行蛋白共价自组装的肽链接头的组合 |
| GB202106361D0 (en) | 2021-05-04 | 2021-06-16 | Spybiotech Ltd | Viral vectored vaccines |
| US20240240203A1 (en) | 2021-05-04 | 2024-07-18 | SpyBiotech Limited | Adenoviral vectors and vaccines thereof |
| WO2023049774A1 (en) * | 2021-09-21 | 2023-03-30 | University Of Washington | Genetically encoded and exogenously triggered protein-protein ligation |
| CN113862235B (zh) * | 2021-09-24 | 2024-07-05 | 苏州近岸蛋白质科技股份有限公司 | 一种嵌合酶及其在体外一步反应合成Cap0 mRNA的用途和方法 |
| GB202117283D0 (en) | 2021-11-30 | 2022-01-12 | Univ Oxford Innovation Ltd | Switchable polypeptide and its use for gentle affinity purification |
| WO2023102156A1 (en) | 2021-12-03 | 2023-06-08 | Wisconsin Alumni Research Foundation | Mutant ace2 proteins and methods of using same |
| US12043862B2 (en) | 2021-12-28 | 2024-07-23 | Encodia, Inc. | High-throughput serotyping and antibody profiling assays |
| CN114672505A (zh) * | 2022-03-15 | 2022-06-28 | 江苏省中国科学院植物研究所 | 一种功能性表达细胞色素p450酶的方法及其应用 |
| CN114732898B (zh) * | 2022-04-01 | 2023-05-09 | 中国人民解放军军事科学院军事医学研究院 | 一种CpG佐剂与抗原定点共价结合方法 |
| WO2024006532A2 (en) * | 2022-06-30 | 2024-01-04 | La Jolla Institute For Immunology | Kari nanoparticle |
| CN116284278B (zh) * | 2022-07-22 | 2025-10-03 | 南京工业大学 | 一种高酯键形成效率分子肽突变体 |
| WO2024064112A2 (en) * | 2022-09-19 | 2024-03-28 | The Rockefeller University | Affinity capturing and directly determining structures of proteins and other materials on superparamagnetic beads by cryo-electron microscopy single-particle analysis |
| JP2025534309A (ja) | 2022-09-28 | 2025-10-15 | ヴァリンク セラピューティクス リミテッド | 多価タンパク質およびスクリーニング法 |
| CN116047055A (zh) * | 2022-11-18 | 2023-05-02 | 常州伯仪生物科技有限公司 | 一种大规模定向标记碱性磷酸酶的方法 |
| CN116165377A (zh) * | 2023-04-21 | 2023-05-26 | 常州伯仪生物科技有限公司 | 一种通过竞争elisa法进行标签蛋白定量的方法 |
| GB202306808D0 (en) | 2023-05-09 | 2023-06-21 | Univ Oxford Innovation Ltd | Method for detecting interactions |
| GB202313175D0 (en) | 2023-08-30 | 2023-10-11 | Univ Oxford Innovation Ltd | A bivalent polypeptide scaffold and uses thereof |
| TW202528546A (zh) | 2023-09-07 | 2025-07-16 | 美商再生元醫藥公司 | 經共價表面修飾之腺相關病毒的生產及純化 |
| GB202315107D0 (en) | 2023-10-02 | 2023-11-15 | Univ Oxford Innovation Ltd | Polypeptides and peptide tags capable of spontaneous isopeptide bond formation at low temperature and low pH and uses thereof |
| TW202540433A (zh) | 2023-11-21 | 2025-10-16 | 美商再生元醫藥公司 | 藉由活體外接合產生共價表面修飾之腺相關病毒及共價表面修飾的腺相關病毒之純化 |
| GB202317925D0 (en) | 2023-11-23 | 2024-01-10 | Spybiotech Ltd | Vaccines |
| WO2025135040A1 (ja) * | 2023-12-18 | 2025-06-26 | 公立大学法人大阪 | イソペプチド結合形成による新規ポリペプチドの作製方法 |
| WO2026050618A1 (en) | 2024-08-29 | 2026-03-05 | Regeneron Pharmaceuticals, Inc. | Polynucleotide constructs and cell lines for recombinant aav production |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU530410B2 (en) | 1978-02-21 | 1983-07-14 | Sintef | Preparing aqueous emulsions |
| US6936252B2 (en) * | 1998-07-27 | 2005-08-30 | Microbial Technics Limited | Streptococcus pneumoniae proteins and nucleic acid molecules |
| ATE361365T1 (de) * | 1998-07-27 | 2007-05-15 | Sanofi Pasteur Ltd | Streptococcus pneumoniae proteine und nukleinsäuren |
| DE10108263A1 (de) * | 2001-02-21 | 2002-09-05 | Max Planck Gesellschaft | Analyse von Modifizierungen und Demodifizierungen von Proteinen mit Ubiquitinverwandten Proteinen mittels FRET (Fluorescence Resonance Energy Transfer) |
| JPWO2004031243A1 (ja) * | 2002-10-01 | 2006-02-02 | 財団法人くまもとテクノ産業財団 | タンパク質ポリマー及びその製造方法 |
| TWI341844B (en) * | 2006-02-02 | 2011-05-11 | Trimeris Inc | Hiv fusion inhibitor peptides with improved biological properties |
| US20110097360A1 (en) * | 2007-05-25 | 2011-04-28 | Claudio Donati | Streptococcus pneumoniae pilus antigens |
| GB0714963D0 (en) * | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| EP2215227A2 (en) * | 2007-11-05 | 2010-08-11 | Promega Corporation | Hybrid fusion reporter and uses thereof |
| GB201002362D0 (en) * | 2010-02-11 | 2010-03-31 | Isis Innovation | Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds |
| FR2973032A1 (fr) | 2011-03-24 | 2012-09-28 | Commissariat Energie Atomique | Peptides aptes a former un complexe covalent et leurs utilisations |
| US20120259101A1 (en) | 2011-04-11 | 2012-10-11 | Li Tan | Isopeptide Bond Formation in Bacillus Species and Uses Thereof |
| EP3008094B1 (en) | 2013-06-14 | 2018-12-26 | Pacific Biosciences Of California, Inc. | Bis-biotinylation tags |
| WO2015156870A2 (en) | 2014-01-15 | 2015-10-15 | Massachusetts Institute Of Technology | Biopolymer-mediated assembly of nanoparticles using genetically encoded proteins |
| GB201509782D0 (en) * | 2015-06-05 | 2015-07-22 | Isis Innovation | Methods and products for fusion protein synthesis |
-
2015
- 2015-06-05 GB GBGB1509782.7A patent/GB201509782D0/en not_active Ceased
-
2016
- 2016-06-03 CN CN202211548024.1A patent/CN116199733A/zh active Pending
- 2016-06-03 KR KR1020187000488A patent/KR102818627B1/ko active Active
- 2016-06-03 ES ES16728359T patent/ES2880336T3/es active Active
- 2016-06-03 AU AU2016272543A patent/AU2016272543B2/en active Active
- 2016-06-03 DK DK16728359.7T patent/DK3303374T3/da active
- 2016-06-03 CN CN201680037511.8A patent/CN108026148B/zh active Active
- 2016-06-03 WO PCT/GB2016/051640 patent/WO2016193746A1/en not_active Ceased
- 2016-06-03 EP EP16728359.7A patent/EP3303374B1/en active Active
- 2016-06-03 US US15/578,486 patent/US10526379B2/en active Active
- 2016-06-03 JP JP2017563189A patent/JP6883529B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20180244730A1 (en) | 2018-08-30 |
| CN108026148A (zh) | 2018-05-11 |
| EP3303374B1 (en) | 2021-03-31 |
| EP3303374A1 (en) | 2018-04-11 |
| KR20180050640A (ko) | 2018-05-15 |
| DK3303374T3 (da) | 2021-07-05 |
| JP2018521640A (ja) | 2018-08-09 |
| ES2880336T3 (es) | 2021-11-24 |
| JP6883529B2 (ja) | 2021-06-09 |
| AU2016272543A1 (en) | 2018-01-04 |
| CN108026148B (zh) | 2022-12-30 |
| WO2016193746A1 (en) | 2016-12-08 |
| US10526379B2 (en) | 2020-01-07 |
| BR112017026042A2 (pt) | 2018-08-14 |
| KR102818627B1 (ko) | 2025-06-10 |
| AU2016272543B2 (en) | 2020-08-13 |
| CA2987821A1 (en) | 2016-12-08 |
| CN116199733A (zh) | 2023-06-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |