GB201506869D0 - Method - Google Patents

Method

Info

Publication number
GB201506869D0
GB201506869D0 GBGB1506869.5A GB201506869A GB201506869D0 GB 201506869 D0 GB201506869 D0 GB 201506869D0 GB 201506869 A GB201506869 A GB 201506869A GB 201506869 D0 GB201506869 D0 GB 201506869D0
Authority
GB
United Kingdom
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1506869.5A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Biopharma SRL
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Priority to GBGB1506869.5A priority Critical patent/GB201506869D0/en
Publication of GB201506869D0 publication Critical patent/GB201506869D0/en
Priority to CA2983537A priority patent/CA2983537A1/en
Priority to US15/568,018 priority patent/US10829565B2/en
Priority to MX2017013419A priority patent/MX2017013419A/es
Priority to BR112017022472A priority patent/BR112017022472A2/pt
Priority to JP2017555395A priority patent/JP6901402B2/ja
Priority to PCT/EP2016/059050 priority patent/WO2016170137A1/en
Priority to EA201792325A priority patent/EA201792325A1/ru
Priority to CN201680031354.XA priority patent/CN107683290B/zh
Priority to SG11201708430VA priority patent/SG11201708430VA/en
Priority to AU2016251960A priority patent/AU2016251960A1/en
Priority to KR1020177033852A priority patent/KR20170138551A/ko
Priority to EP16721103.6A priority patent/EP3286220A1/en
Priority to IL255094A priority patent/IL255094A0/en
Priority to CL2017002677A priority patent/CL2017002677A1/es
Priority to CONC2017/0010845A priority patent/CO2017010845A2/es
Priority to US17/078,130 priority patent/US11834514B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/624—Disulfide-stabilized antibody (dsFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/66—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a swap of domains, e.g. CH3-CH2, VH-CL or VL-CH1

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GBGB1506869.5A 2015-04-22 2015-04-22 Method Ceased GB201506869D0 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
GBGB1506869.5A GB201506869D0 (en) 2015-04-22 2015-04-22 Method
EP16721103.6A EP3286220A1 (en) 2015-04-22 2016-04-22 Method for increasing the percentage of monomeric antibody fab-dsfv multimeric species
CN201680031354.XA CN107683290B (zh) 2015-04-22 2016-04-22 用于增加单体抗体fab-dsfv多聚体种类的百分比的方法
AU2016251960A AU2016251960A1 (en) 2015-04-22 2016-04-22 Method for increasing the percentage of monomeric antibody Fab-dsFv multimeric species
MX2017013419A MX2017013419A (es) 2015-04-22 2016-04-22 Metodo para aumentar el porcentaje de las especies multimericas de fragmento de union a antigeno-fragmento variable de disulfuro (fab-dsfv) del anticuerpo monomerico.
BR112017022472A BR112017022472A2 (pt) 2015-04-22 2016-04-22 método para aumentar a porcentagem de anticorpo monomérico fab-dsfv espécies multiméricas
JP2017555395A JP6901402B2 (ja) 2015-04-22 2016-04-22 単量体抗体Ｆａｂ−ｄｓＦｖ多量体種のパーセンテージを増加させる方法
PCT/EP2016/059050 WO2016170137A1 (en) 2015-04-22 2016-04-22 Method for increasing the percentage of monomeric antibody fab-dsfv multimeric species
EA201792325A EA201792325A1 (ru) 2015-04-22 2016-04-22 Способ увеличения процентного содержания мономерного антитела в fab-dsfv мультимерных частицах
CA2983537A CA2983537A1 (en) 2015-04-22 2016-04-22 Method for increasing the percentage of monomeric antibody fab-dsfv multimeric species
SG11201708430VA SG11201708430VA (en) 2015-04-22 2016-04-22 Method for increasing the percentage of monomeric antibody fab-dsfv multimeric species
US15/568,018 US10829565B2 (en) 2015-04-22 2016-04-22 Method for increasing the percentage of monomeric antibody Fab-dsFv multimeric species
KR1020177033852A KR20170138551A (ko) 2015-04-22 2016-04-22 Fab-dsFv 다량체 종에서 단량체 항체의 백분율을 증가시키는 방법
IL255094A IL255094A0 (en) 2015-04-22 2017-10-17 A method for increasing the percentage of multimeric strains for a monomeric dsfv-fab antibody
CL2017002677A CL2017002677A1 (es) 2015-04-22 2017-10-20 Método para incrementar el porcentaje de anticuerpos monoméricos fab-dsfv de especies multiméricas
CONC2017/0010845A CO2017010845A2 (es) 2015-04-22 2017-10-25 Método para aumentar el porcentaje de las especies multiméricas de fragmento de unión a antígeno-fragmento variable de disulfuro (fab-dsfv) del anticuerpo monomérico
US17/078,130 US11834514B2 (en) 2015-04-22 2020-10-23 Method for increasing the percentage of monomeric antibody Fab-dsFv multimeric species

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1506869.5A GB201506869D0 (en) 2015-04-22 2015-04-22 Method

Publications (1)

Publication Number Publication Date
GB201506869D0 true GB201506869D0 (en) 2015-06-03

Family

ID=53299018

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1506869.5A Ceased GB201506869D0 (en) 2015-04-22 2015-04-22 Method

Country Status (16)

Country Link
US (2) US10829565B2 (https=)
EP (1) EP3286220A1 (https=)
JP (1) JP6901402B2 (https=)
KR (1) KR20170138551A (https=)
CN (1) CN107683290B (https=)
AU (1) AU2016251960A1 (https=)
BR (1) BR112017022472A2 (https=)
CA (1) CA2983537A1 (https=)
CL (1) CL2017002677A1 (https=)
CO (1) CO2017010845A2 (https=)
EA (1) EA201792325A1 (https=)
GB (1) GB201506869D0 (https=)
IL (1) IL255094A0 (https=)
MX (1) MX2017013419A (https=)
SG (1) SG11201708430VA (https=)
WO (1) WO2016170137A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201223276D0 (en) * 2012-12-21 2013-02-06 Ucb Pharma Sa Antibodies and methods of producing same
GB201411320D0 (en) 2014-06-25 2014-08-06 Ucb Biopharma Sprl Antibody construct
GB201506868D0 (en) 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method for protein purification
GB201506870D0 (en) * 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method
GB201506869D0 (en) * 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method
DK3551664T3 (da) * 2016-12-09 2021-05-03 Ose Immunotherapeutics Antistoffer og polypeptider rettet mod cd127

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GB201506868D0 (en) 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method for protein purification
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Also Published As

Publication number Publication date
SG11201708430VA (en) 2017-11-29
CN107683290B (zh) 2022-01-04
EA201792325A1 (ru) 2018-04-30
IL255094A0 (en) 2017-12-31
CO2017010845A2 (es) 2018-03-20
JP6901402B2 (ja) 2021-07-14
CL2017002677A1 (es) 2018-03-23
EP3286220A1 (en) 2018-02-28
CA2983537A1 (en) 2016-10-27
JP2018515453A (ja) 2018-06-14
BR112017022472A2 (pt) 2018-07-17
WO2016170137A1 (en) 2016-10-27
KR20170138551A (ko) 2017-12-15
AU2016251960A1 (en) 2017-11-02
CN107683290A (zh) 2018-02-09
US20180142039A1 (en) 2018-05-24
US20210079120A1 (en) 2021-03-18
US11834514B2 (en) 2023-12-05
US10829565B2 (en) 2020-11-10
MX2017013419A (es) 2018-02-09

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