GB201321242D0 - Immunogenic compound - Google Patents

Immunogenic compound

Info

Publication number
GB201321242D0
GB201321242D0 GBGB1321242.8A GB201321242A GB201321242D0 GB 201321242 D0 GB201321242 D0 GB 201321242D0 GB 201321242 A GB201321242 A GB 201321242A GB 201321242 D0 GB201321242 D0 GB 201321242D0
Authority
GB
United Kingdom
Prior art keywords
immunogenic compound
immunogenic
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1321242.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Altimmune UK Ltd
Original Assignee
Immune Targeting Systems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immune Targeting Systems Ltd filed Critical Immune Targeting Systems Ltd
Priority to GBGB1321242.8A priority Critical patent/GB201321242D0/en
Publication of GB201321242D0 publication Critical patent/GB201321242D0/en
Priority to CA2931933A priority patent/CA2931933A1/en
Priority to EP14809960.9A priority patent/EP3077052A1/en
Priority to US15/100,800 priority patent/US9962453B2/en
Priority to BR112016012528A priority patent/BR112016012528A2/pt
Priority to CN201480071742.1A priority patent/CN105873638A/zh
Priority to PCT/GB2014/053577 priority patent/WO2015082905A1/en
Priority to EA201691146A priority patent/EA201691146A1/ru
Priority to JP2016555933A priority patent/JP6792452B2/ja
Priority to KR1020167017734A priority patent/KR102356869B1/ko
Priority to US15/968,839 priority patent/US10434183B2/en
Priority to US16/595,311 priority patent/US10849984B2/en
Priority to JP2020185572A priority patent/JP7095053B2/ja
Priority to US17/091,106 priority patent/US20210145975A1/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GBGB1321242.8A 2013-12-02 2013-12-02 Immunogenic compound Ceased GB201321242D0 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
GBGB1321242.8A GB201321242D0 (en) 2013-12-02 2013-12-02 Immunogenic compound
KR1020167017734A KR102356869B1 (ko) 2013-12-02 2014-12-02 면역원성 화합물
PCT/GB2014/053577 WO2015082905A1 (en) 2013-12-02 2014-12-02 Immunogenic compound
JP2016555933A JP6792452B2 (ja) 2013-12-02 2014-12-02 免疫原性化合物
US15/100,800 US9962453B2 (en) 2013-12-02 2014-12-02 Immunogenic compound
BR112016012528A BR112016012528A2 (pt) 2013-12-02 2014-12-02 composto imunogênico
CN201480071742.1A CN105873638A (zh) 2013-12-02 2014-12-02 免疫原性化合物
CA2931933A CA2931933A1 (en) 2013-12-02 2014-12-02 Immunogenic compound
EA201691146A EA201691146A1 (ru) 2013-12-02 2014-12-02 Иммуногенное соединение
EP14809960.9A EP3077052A1 (en) 2013-12-02 2014-12-02 Immunogenic compound
US15/968,839 US10434183B2 (en) 2013-12-02 2018-05-02 Immunogenic compound
US16/595,311 US10849984B2 (en) 2013-12-02 2019-10-07 Immunogenic compound
JP2020185572A JP7095053B2 (ja) 2013-12-02 2020-11-06 免疫原性化合物
US17/091,106 US20210145975A1 (en) 2013-12-02 2020-11-06 Immunogenic compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1321242.8A GB201321242D0 (en) 2013-12-02 2013-12-02 Immunogenic compound

Publications (1)

Publication Number Publication Date
GB201321242D0 true GB201321242D0 (en) 2014-01-15

Family

ID=49979653

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1321242.8A Ceased GB201321242D0 (en) 2013-12-02 2013-12-02 Immunogenic compound

Country Status (10)

Country Link
US (4) US9962453B2 (https=)
EP (1) EP3077052A1 (https=)
JP (2) JP6792452B2 (https=)
KR (1) KR102356869B1 (https=)
CN (1) CN105873638A (https=)
BR (1) BR112016012528A2 (https=)
CA (1) CA2931933A1 (https=)
EA (1) EA201691146A1 (https=)
GB (1) GB201321242D0 (https=)
WO (1) WO2015082905A1 (https=)

Families Citing this family (19)

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Publication number Priority date Publication date Assignee Title
WO2015077717A1 (en) 2013-11-25 2015-05-28 The Broad Institute Inc. Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
GB201321242D0 (en) * 2013-12-02 2014-01-15 Immune Targeting Systems Its Ltd Immunogenic compound
WO2015085147A1 (en) 2013-12-05 2015-06-11 The Broad Institute Inc. Polymorphic gene typing and somatic change detection using sequencing data
KR20230076867A (ko) 2013-12-20 2023-05-31 더 브로드 인스티튜트, 인코퍼레이티드 신생항원 백신과의 병용 요법
EP3234130B1 (en) 2014-12-19 2020-11-25 The Broad Institute, Inc. Methods for profiling the t-cell- receptor repertoire
US10975442B2 (en) 2014-12-19 2021-04-13 Massachusetts Institute Of Technology Molecular biomarkers for cancer immunotherapy
CN109843327B (zh) 2016-07-07 2022-05-13 小利兰·斯坦福大学托管委员会 抗体佐剂缀合物
US11464854B2 (en) * 2017-03-23 2022-10-11 Children's Medical Center Corporation Methods and compositions relating to adjuvants
WO2018187515A1 (en) 2017-04-04 2018-10-11 Avidea Technologies, Inc. Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response
ES2951817T3 (es) 2017-08-22 2023-10-25 Dynavax Tech Corp Derivados de imidazoquinolina de cadena alquílica modificada como agonistas de TLR7/8 y usos de los mismos
US10722591B2 (en) 2017-11-14 2020-07-28 Dynavax Technologies Corporation Cleavable conjugates of TLR7/8 agonist compounds, methods for preparation, and uses thereof
KR20250078621A (ko) * 2018-07-10 2025-06-02 세퀴러스 피티와이 리미티드 응집체의 제거
WO2020190725A1 (en) 2019-03-15 2020-09-24 Bolt Biotherapeutics, Inc. Immunoconjugates targeting her2
WO2020205996A2 (en) * 2019-04-01 2020-10-08 Altimmune Uk Ltd Locally acting toll-like receptor 7 (tlr7) and/or tlr8 agonist immunotherapy compounds and their uses
WO2023085956A1 (en) * 2021-11-09 2023-05-19 Avalia Immunotherapies Limited Novel therapeutic vaccines
US20250360205A1 (en) * 2022-06-09 2025-11-27 Academia Sinica Nod1 modulators and uses thereof
US12531162B1 (en) * 2023-05-31 2026-01-20 Northeastern University Multi-dimensional phenotypic space for genotype to phenotype mapping and intelligent design of cancer drug therapies using a deep learning net
US12562256B2 (en) * 2023-11-07 2026-02-24 New York University Systems, methods and computer-accessible medium for identifying target pairs for CAR-T therapy
KR102784104B1 (ko) * 2024-04-04 2025-03-24 대한민국(방위사업청장) 이미퀴모드 및 Nod2 수용체 자극 성분 또는 박테리아를 포함하는 면역 어쥬번트

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US4801575A (en) 1986-07-30 1989-01-31 The Regents Of The University Of California Chimeric peptides for neuropeptide delivery through the blood-brain barrier
US5294605A (en) 1990-07-19 1994-03-15 The Scripps Research Institute Amphiphilic peptide compositions and analogues thereof
FR2744123B1 (fr) * 1996-01-26 1998-04-17 Carelli Claude Marcel Henri Molecules biologiquement actives plus particulierement peptidiques ayant un effet potentialisateur de l'activite biologique de l'hormone de croissance
ES2312659T3 (es) 2001-11-29 2009-03-01 3M Innovative Properties Company Formulaciones farmaceuticas que comprenden un modificador de la respuesta inmune.
DK1545597T3 (da) 2002-08-15 2011-01-31 3M Innovative Properties Co Immunstimulerende sammensætninger og fremgangsmåde til stimulering af en immunrespons
CA2545825A1 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Hydroxylamine substituted imidazo ring compounds
GB0408164D0 (en) 2004-04-13 2004-05-19 Immune Targeting Systems Ltd Antigen delivery vectors and constructs
GB0716992D0 (en) 2007-08-31 2007-10-10 Immune Targeting Systems Its L Influenza antigen delivery vectors and constructs
CA2605808A1 (en) 2005-04-25 2006-11-02 3M Innovative Properties Company Immunostimulatory compositions
CN101790380B (zh) 2007-02-07 2013-07-10 加利福尼亚大学董事会 合成tlr激动剂的缀合物及其应用
ES2532896T5 (es) * 2008-05-14 2018-03-20 Immatics Biotechnologies Gmbh Péptidos del MHC de clase II novedosos y potentes derivados de survivina y neurocan
TR201802083T4 (tr) 2008-10-24 2018-03-21 Glaxosmithkline Biologicals Sa Lipidatlı imidazokinolin türevleri.
EP2387421A1 (en) * 2009-01-14 2011-11-23 SKU Asset Management GmbH Compounds comprising n-formyl-methionine residues and tumor-targeting peptides
JP2013512859A (ja) 2009-12-03 2013-04-18 大日本住友製薬株式会社 トール様受容体(tlr)を介して作用するイミダゾキノリン
US8916162B2 (en) 2010-02-20 2014-12-23 Alexey Gennadievich Zdanovsky Botulinum neurotoxin antigenic compositions and methods
US9242980B2 (en) 2010-08-17 2016-01-26 3M Innovative Properties Company Lipidated immune response modifier compound compositions, formulations, and methods
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WO2012113413A1 (en) * 2011-02-21 2012-08-30 Curevac Gmbh Vaccine composition comprising complexed immunostimulatory nucleic acids and antigens packaged with disulfide-linked polyethyleneglycol/peptide conjugates
US8728486B2 (en) 2011-05-18 2014-05-20 University Of Kansas Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds
JP6460789B2 (ja) 2011-06-03 2019-01-30 スリーエム イノベイティブ プロパティズ カンパニー ポリエチレングリコールセグメントを有するヘテロ2官能性リンカー及び該リンカーから調製された免疫反応調節複合体
GB201321242D0 (en) * 2013-12-02 2014-01-15 Immune Targeting Systems Its Ltd Immunogenic compound

Also Published As

Publication number Publication date
US20190125889A1 (en) 2019-05-02
WO2015082905A1 (en) 2015-06-11
US9962453B2 (en) 2018-05-08
JP6792452B2 (ja) 2020-11-25
US20200038519A1 (en) 2020-02-06
US10849984B2 (en) 2020-12-01
US10434183B2 (en) 2019-10-08
US20210145975A1 (en) 2021-05-20
BR112016012528A2 (pt) 2017-09-26
US20160310603A1 (en) 2016-10-27
JP2021020967A (ja) 2021-02-18
JP7095053B2 (ja) 2022-07-04
EA201691146A1 (ru) 2016-12-30
KR102356869B1 (ko) 2022-01-27
JP2016540050A (ja) 2016-12-22
EP3077052A1 (en) 2016-10-12
KR20160113104A (ko) 2016-09-28
CN105873638A (zh) 2016-08-17
CA2931933A1 (en) 2015-06-11

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)