GB201018518D0 - Novel endolysin - Google Patents
Novel endolysinInfo
- Publication number
- GB201018518D0 GB201018518D0 GBGB1018518.9A GB201018518A GB201018518D0 GB 201018518 D0 GB201018518 D0 GB 201018518D0 GB 201018518 A GB201018518 A GB 201018518A GB 201018518 D0 GB201018518 D0 GB 201018518D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- polypeptide
- relates
- present
- fusion protein
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 title abstract 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N lysine Chemical compound NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title abstract 2
- 102000037865 fusion proteins Human genes 0.000 abstract 5
- 108020001507 fusion proteins Proteins 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 239000012634 fragment Substances 0.000 abstract 4
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 230000002265 prevention Effects 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000011109 contamination Methods 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000027096 gram-negative bacterial infections Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011012 sanitization Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2462—Lysozyme (3.2.1.17)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
- A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
- A23B2/729—Organic compounds; Microorganisms; Enzymes
- A23B2/783—Microorganisms; Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01017—Lysozyme (3.2.1.17)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/01028—N-Acetylmuramoyl-L-alanine amidase (3.5.1.28)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Food Science & Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Polymers & Plastics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Cosmetics (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1018518.9A GB201018518D0 (en) | 2010-11-03 | 2010-11-03 | Novel endolysin |
| BR112013010844A BR112013010844A2 (pt) | 2010-11-03 | 2011-11-03 | nova endolisina |
| EP20110778880 EP2635676B1 (en) | 2010-11-03 | 2011-11-03 | Novel endolysin |
| CN2011800531787A CN103201381A (zh) | 2010-11-03 | 2011-11-03 | 新的细胞内溶素 |
| JP2013537132A JP2014500714A (ja) | 2010-11-03 | 2011-11-03 | 新規エンドリシン |
| US13/883,240 US20140017224A1 (en) | 2010-11-03 | 2011-11-03 | Novel endolysin |
| PCT/EP2011/069336 WO2012059545A1 (en) | 2010-11-03 | 2011-11-03 | Novel endolysin |
| TW100140109A TW201300539A (zh) | 2010-11-03 | 2011-11-03 | 新型內溶素 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1018518.9A GB201018518D0 (en) | 2010-11-03 | 2010-11-03 | Novel endolysin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201018518D0 true GB201018518D0 (en) | 2010-12-15 |
Family
ID=43401687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1018518.9A Ceased GB201018518D0 (en) | 2010-11-03 | 2010-11-03 | Novel endolysin |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20140017224A1 (https=) |
| EP (1) | EP2635676B1 (https=) |
| JP (1) | JP2014500714A (https=) |
| CN (1) | CN103201381A (https=) |
| BR (1) | BR112013010844A2 (https=) |
| GB (1) | GB201018518D0 (https=) |
| TW (1) | TW201300539A (https=) |
| WO (1) | WO2012059545A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013024421A1 (en) * | 2011-08-12 | 2013-02-21 | Universidade Do Minho | Peptides and derivatives thereof for detection and control of salmonella |
| RU2547584C2 (ru) * | 2012-12-05 | 2015-04-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Гидролаза пептидогликана, экспрессионная плазмида, содержащая фрагмент днк, кодирующий гидролазу пептидогликана, бактерия-продуцент и способ микробиологического синтеза гидролазы пептидогликана |
| WO2015070911A1 (en) * | 2013-11-14 | 2015-05-21 | Lysando Ag | Modified kz144 endolysin sequence |
| EP3105322B1 (en) | 2014-02-14 | 2018-12-12 | Lysando AG | Antimicrobial agents |
| US10588980B2 (en) * | 2014-06-23 | 2020-03-17 | Novartis Ag | Fatty acids and their use in conjugation to biomolecules |
| CN105062992B (zh) * | 2015-07-20 | 2018-05-11 | 昆明理工大学 | 一种细胞内溶素和编码此细胞内溶素的多核苷酸 |
| WO2017203471A1 (en) * | 2016-05-27 | 2017-11-30 | Sasinapas Co., Ltd. | Endolysin variant |
| CN110300760B (zh) * | 2016-12-16 | 2023-10-20 | 米尼奥大学 | 新的内溶素 |
| WO2019118632A1 (en) * | 2017-12-12 | 2019-06-20 | Contrafect Corporation | Identification of lysins and derivatives thereof with bacterial activity against pseudomonas aeruginosa |
| AU2019276253A1 (en) | 2018-05-30 | 2020-11-26 | Lysando Ag | Novel antimicrobial proteins |
| MX2021013491A (es) * | 2019-05-08 | 2022-02-21 | Phagomed Biopharma Gmbh | Nuevas endolisinas de gardnerella y usos de las mismas. |
| CA3171721A1 (en) | 2020-03-19 | 2021-09-23 | Fritz Eichenseher | A stabilized protein of interest |
| CN116410329A (zh) * | 2021-12-30 | 2023-07-11 | 上海高科生物工程有限公司 | 一种c末端修饰的杂合抗菌蛋白及其药物组合物和应用 |
| WO2023139605A1 (en) * | 2022-01-20 | 2023-07-27 | Techinvention Lifecare Pvt. Ltd. | Lysin polypeptides and compositions thereof against urinary tract infection caused by drug-resistant gram- negative bacteria |
| CN114807104B (zh) * | 2022-04-11 | 2024-02-20 | 西南大学 | 肺炎克雷伯菌噬菌体裂解酶及其制备方法和应用 |
| WO2024241070A1 (en) | 2023-05-22 | 2024-11-28 | L'oreal | Cosmetic composition comprising an endolysin and a polyvinyl alcohol |
| FR3149202B1 (fr) | 2023-06-02 | 2026-04-10 | Oreal | Composition cosmétique comprenant une endolysine dérivée de phage de Staphylococcus aureus et une huile. |
| FR3149205B1 (fr) | 2023-06-02 | 2026-04-24 | Loreal | Composition cosmétique comprenant une endolysine et un agent de charge organique |
| FR3149209B1 (fr) | 2023-06-02 | 2026-04-03 | Oreal | Composition cosmétique comprenant une endolysine dérivée de phage de Staphylococcus aureus et un alcool aromatique |
| FR3149203B1 (fr) | 2023-06-02 | 2026-03-13 | Oreal | Composition anhydre comprenant une endolysine et de l’hydroxypropylmethylcellulose et/ou du pullulane |
| FR3149206B1 (fr) | 2023-06-02 | 2026-03-13 | Oreal | Composition cosmétique aqueuse comprenant une endolysine et du tréhalose |
| FR3149208B1 (fr) | 2023-06-02 | 2026-03-20 | Oreal | Composition cosmétique, notamment aqueuse, comprenant une endolysine et un pullulane |
| FR3149207B1 (fr) | 2023-06-02 | 2026-03-13 | Oreal | Composition cosmétique comprenant une endolysine et un composé de formule (I) |
| FR3152395A1 (fr) | 2023-08-28 | 2025-03-07 | L'oreal | Composition cosmétique comprenant une endolysine dérivée de phage de Staphylococcus aureus et la 4-hydroxyacetophenone |
| FR3149204B1 (fr) | 2023-06-02 | 2026-02-13 | Oreal | Composition cosmétique comprenant une endolysine et un tensioactif non ionique comprenant un résidu carbohydrate |
| EP4719330A1 (en) | 2023-06-02 | 2026-04-08 | L'oreal | Cosmetic composition comprising an endolysin derived from a staphylococcus aureus phage and an aromatic alcohol |
| CN116536289B (zh) * | 2023-06-21 | 2023-09-15 | 中国农业科学院生物技术研究所 | 具有溶菌活性的几丁质酶及其突变体和应用 |
| FR3152394B1 (fr) | 2023-08-28 | 2026-04-24 | Loreal | Composition cosmétique comprenant une endolysine et des particules d’aérogel de silice hydrophobe |
| FR3152396A1 (fr) | 2023-08-28 | 2025-03-07 | L'oreal | Composition cosmétique comprenant une endolysine dérivée de phage de Staphylococcus aureus et un polyhydroxyalcane |
| FR3152393B1 (fr) | 2023-08-28 | 2026-04-24 | Loreal | Composition cosmétique comprenant une endolysine dérivée d’un phage de Staphylococcus aureus et une charge minérale |
| WO2025093666A1 (en) | 2023-11-01 | 2025-05-08 | University Of Copenhagen | Treatment of lymphoma |
| WO2026052743A1 (en) | 2024-09-04 | 2026-03-12 | Micreos Human Health B.V. | Reduction of trans-epidermal water loss by a polypeptide with antibacterial properties |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8816693D0 (en) | 1988-07-13 | 1988-08-17 | Agricultural & Food Res | Viral enzyme & gene |
| GB0815484D0 (en) | 2008-08-26 | 2008-10-01 | Univ Leuven Kath | Antibacterial agents |
-
2010
- 2010-11-03 GB GBGB1018518.9A patent/GB201018518D0/en not_active Ceased
-
2011
- 2011-11-03 CN CN2011800531787A patent/CN103201381A/zh active Pending
- 2011-11-03 EP EP20110778880 patent/EP2635676B1/en not_active Not-in-force
- 2011-11-03 BR BR112013010844A patent/BR112013010844A2/pt not_active IP Right Cessation
- 2011-11-03 WO PCT/EP2011/069336 patent/WO2012059545A1/en not_active Ceased
- 2011-11-03 JP JP2013537132A patent/JP2014500714A/ja active Pending
- 2011-11-03 TW TW100140109A patent/TW201300539A/zh unknown
- 2011-11-03 US US13/883,240 patent/US20140017224A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2635676B1 (en) | 2015-04-22 |
| US20140017224A1 (en) | 2014-01-16 |
| CN103201381A (zh) | 2013-07-10 |
| JP2014500714A (ja) | 2014-01-16 |
| TW201300539A (zh) | 2013-01-01 |
| BR112013010844A2 (pt) | 2019-09-24 |
| WO2012059545A1 (en) | 2012-05-10 |
| EP2635676A1 (en) | 2013-09-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |