EA201991233A1 - Новый эндолизин - Google Patents

Новый эндолизин

Info

Publication number
EA201991233A1
EA201991233A1 EA201991233A EA201991233A EA201991233A1 EA 201991233 A1 EA201991233 A1 EA 201991233A1 EA 201991233 A EA201991233 A EA 201991233A EA 201991233 A EA201991233 A EA 201991233A EA 201991233 A1 EA201991233 A1 EA 201991233A1
Authority
EA
Eurasian Patent Office
Prior art keywords
polypeptide
relates
present
nucleic acid
acid molecules
Prior art date
Application number
EA201991233A
Other languages
English (en)
Inventor
Уго Александре Мендес Де Оливейра
Хоана Сесилия Валенте Де Родригес Асередо
Original Assignee
Универсидаде До Мино
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Универсидаде До Мино filed Critical Универсидаде До Мино
Publication of EA201991233A1 publication Critical patent/EA201991233A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462—Lysozyme (3.2.1.17)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01017—Lysozyme (3.2.1.17)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3571—Microorganisms; Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/524—Preservatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Animal Husbandry (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение относится к полипептиду с активностью эндолизина и аминокислотными последовательностями, соответствующими SEQ ID NO: 1, и к его фрагментам или производным. Кроме того, настоящее изобретение относится к молекулам нуклеиновой кислоты, кодирующим указанный полипептид, векторам, содержащим указанные молекулы нуклеиновой кислоты, и клеткам-хозяевам, содержащим указанные молекулы нуклеиновой кислоты или указанные векторы. В дополнение к этому настоящее изобретение относится к указанному полипептиду для применения в качестве лекарственного средства, в частности для лечения или профилактики грамотрицательных бактериальных инфекций, в качестве средств диагностики, в качестве косметического средства или в качестве средства для санитарной обработки. Настоящее изобретение также относится к применению указанного полипептида для устранения или предотвращения бактериального загрязнения, в частности загрязнения грамотрицательными бактериями, пищевых продуктов, оборудования для производства пищевых продуктов, предприятий по производству пищевых продуктов, поверхностей, находящихся в контакте с пищевыми продуктами, медицинских устройств, поверхностей в больницах и врачебных кабинетах. Кроме того, настоящее изобретение относится к фармацевтической композиции, содержащей указанный полипептид.
EA201991233A 2016-12-16 2017-12-18 Новый эндолизин EA201991233A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16204770 2016-12-16
PCT/EP2017/083326 WO2018109229A1 (en) 2016-12-16 2017-12-18 Novel endolysin

Publications (1)

Publication Number Publication Date
EA201991233A1 true EA201991233A1 (ru) 2020-01-13

Family

ID=57714394

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201991233A EA201991233A1 (ru) 2016-12-16 2017-12-18 Новый эндолизин

Country Status (9)

Country Link
US (1) US20190330609A1 (ru)
EP (1) EP3555121B1 (ru)
JP (1) JP7033596B2 (ru)
KR (1) KR102503567B1 (ru)
CN (1) CN110300760B (ru)
AU (1) AU2017375050B2 (ru)
CA (1) CA3045387A1 (ru)
EA (1) EA201991233A1 (ru)
WO (1) WO2018109229A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6615682B2 (ja) 2016-04-12 2019-12-04 デノラ・ペルメレック株式会社 アルカリ水電解用陽極及びアルカリ水電解用陽極の製造方法
AU2019276253A1 (en) * 2018-05-30 2020-11-26 Lysando Ag Novel antimicrobial proteins
US20210198645A1 (en) * 2018-05-30 2021-07-01 Lysando Ag Novel antimicrobial fusion proteins
KR102228999B1 (ko) * 2020-08-27 2021-03-18 주식회사 라이센텍 폴리펩타이드 변이체 및 이를 포함하는 그람음성균에 대한 항생제
JP2023526388A (ja) * 2020-05-22 2023-06-21 ライセンテク カンパニー リミテッド 新規なポリペプチド、融合ポリペプチド、およびこれを含むグラム陰性菌に対する抗生物質

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0815484D0 (en) * 2008-08-26 2008-10-01 Univ Leuven Kath Antibacterial agents
KR20170024129A (ko) * 2009-06-26 2017-03-06 카톨리에케 유니버시테이트 루벤 항균제
MX2012002216A (es) * 2009-08-24 2012-04-10 Univ Leuven Kath Nueva endolisina obpgplys.
MX340520B (es) * 2010-04-27 2016-07-12 Lysando Ag * Metodo de reduccion de biopeliculas.
GB201018518D0 (en) * 2010-11-03 2010-12-15 Univ Leuven Kath Novel endolysin

Also Published As

Publication number Publication date
US20190330609A1 (en) 2019-10-31
CN110300760B (zh) 2023-10-20
AU2017375050A1 (en) 2019-06-06
CN110300760A (zh) 2019-10-01
EP3555121B1 (en) 2021-09-22
CA3045387A1 (en) 2018-06-21
KR102503567B1 (ko) 2023-02-24
KR20190110094A (ko) 2019-09-27
WO2018109229A1 (en) 2018-06-21
AU2017375050B2 (en) 2021-07-22
JP2020504602A (ja) 2020-02-13
JP7033596B2 (ja) 2022-03-10
EP3555121A1 (en) 2019-10-23

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