GB2009180B - 25-alkylcholestrerol derivatives - Google Patents

25-alkylcholestrerol derivatives

Info

Publication number
GB2009180B
GB2009180B GB7834881A GB7834881A GB2009180B GB 2009180 B GB2009180 B GB 2009180B GB 7834881 A GB7834881 A GB 7834881A GB 7834881 A GB7834881 A GB 7834881A GB 2009180 B GB2009180 B GB 2009180B
Authority
GB
United Kingdom
Prior art keywords
alkylcholestrerol
derivatives
alkylcholestrerol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7834881A
Other languages
English (en)
Other versions
GB2009180A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of GB2009180A publication Critical patent/GB2009180A/en
Application granted granted Critical
Publication of GB2009180B publication Critical patent/GB2009180B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB7834881A 1977-08-29 1978-08-29 25-alkylcholestrerol derivatives Expired GB2009180B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82838577A 1977-08-29 1977-08-29

Publications (2)

Publication Number Publication Date
GB2009180A GB2009180A (en) 1979-06-13
GB2009180B true GB2009180B (en) 1982-05-26

Family

ID=25251653

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7834881A Expired GB2009180B (en) 1977-08-29 1978-08-29 25-alkylcholestrerol derivatives

Country Status (9)

Country Link
JP (1) JPS5448751A (de)
AU (1) AU520334B2 (de)
CA (1) CA1113086A (de)
CH (1) CH643566A5 (de)
DE (1) DE2837414A1 (de)
ES (1) ES472877A1 (de)
FR (1) FR2401935A1 (de)
GB (1) GB2009180B (de)
IT (1) IT1106121B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4225525A (en) * 1979-02-08 1980-09-30 Hoffmann-La Roche Inc. Vitamin D3 metabolite derivatives
US4230626A (en) * 1979-07-30 1980-10-28 G. D. Searle & Co. 25-Halocholest-5-ene-3β,22-diols and esters thereof
US4329295A (en) * 1981-06-29 1982-05-11 G. D. Searle & Co. 24-Cyclopropylcholene-3β, 22-diols and esters thereof
US4348328A (en) * 1981-11-09 1982-09-07 G.D. Searle & Co. 25-Substituted-5α-cholestane-3β,22S-diol
IL105050A0 (en) * 1992-03-27 1993-07-08 Lilly Co Eli Steroid derivatives
US6518262B1 (en) 1999-03-09 2003-02-11 Akzo Nobel N.V. 22R-hydroxycholesta-8, 14-diene derivatives for the inhibition of meiosis
JP2005508281A (ja) * 2001-02-08 2005-03-31 ザ ユニバーシティー オブ シカゴ ステロイド誘導体
US7078396B2 (en) 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
JP2013500986A (ja) 2009-07-29 2013-01-10 ザ・ユニバーシティ・オブ・シカゴ 肝臓ｘ受容体アゴニスト

Also Published As

Publication number Publication date
CA1113086A (en) 1981-11-24
IT7850879A0 (it) 1978-08-28
DE2837414A1 (de) 1979-03-08
ES472877A1 (es) 1979-02-16
AU520334B2 (en) 1982-01-28
AU3931878A (en) 1980-03-06
GB2009180A (en) 1979-06-13
IT1106121B (it) 1985-11-11
DE2837414C2 (de) 1987-09-03
JPS5448751A (en) 1979-04-17
FR2401935B1 (de) 1981-07-10
FR2401935A1 (fr) 1979-03-30
CH643566A5 (de) 1984-06-15
JPS6259720B2 (de) 1987-12-12

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee