GB1598127A - Benzoxazine carboxamides having lipogenesis-inhibiting properties - Google Patents

Benzoxazine carboxamides having lipogenesis-inhibiting properties Download PDF

Info

Publication number
GB1598127A
GB1598127A GB31589/78A GB3158978A GB1598127A GB 1598127 A GB1598127 A GB 1598127A GB 31589/78 A GB31589/78 A GB 31589/78A GB 3158978 A GB3158978 A GB 3158978A GB 1598127 A GB1598127 A GB 1598127A
Authority
GB
United Kingdom
Prior art keywords
ether
solvent
mixture
benzoxazine
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB31589/78A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shell Internationale Research Maatschappij BV
Original Assignee
Shell Internationale Research Maatschappij BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/778,535 external-priority patent/US4118507A/en
Priority claimed from US05/779,648 external-priority patent/US4103021A/en
Application filed by Shell Internationale Research Maatschappij BV filed Critical Shell Internationale Research Maatschappij BV
Publication of GB1598127A publication Critical patent/GB1598127A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB31589/78A 1977-03-17 1978-03-15 Benzoxazine carboxamides having lipogenesis-inhibiting properties Expired GB1598127A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77853477A 1977-03-17 1977-03-17
US77881677A 1977-03-17 1977-03-17
US05/778,535 US4118507A (en) 1977-03-17 1977-03-17 Benzodioxincarboxamide lipogenesis inhibitors
US05/779,648 US4103021A (en) 1977-03-21 1977-03-21 Method of lowering blood lipid levels in mammals
US79175877A 1977-04-28 1977-04-28

Publications (1)

Publication Number Publication Date
GB1598127A true GB1598127A (en) 1981-09-16

Family

ID=27542199

Family Applications (3)

Application Number Title Priority Date Filing Date
GB10303/78A Expired GB1598126A (en) 1977-03-17 1978-03-15 Lipogenesis-inhibiting compositions
GB31590/78A Expired GB1598128A (en) 1977-03-17 1978-03-15 Benzopyran carboxamides having lipogenesis-inhibiting properties
GB31589/78A Expired GB1598127A (en) 1977-03-17 1978-03-15 Benzoxazine carboxamides having lipogenesis-inhibiting properties

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB10303/78A Expired GB1598126A (en) 1977-03-17 1978-03-15 Lipogenesis-inhibiting compositions
GB31590/78A Expired GB1598128A (en) 1977-03-17 1978-03-15 Benzopyran carboxamides having lipogenesis-inhibiting properties

Country Status (11)

Country Link
JP (1) JPS53116377A (xx)
BE (1) BE864918A (xx)
DD (1) DD137714A5 (xx)
DE (1) DE2811236A1 (xx)
DK (1) DK117478A (xx)
FR (1) FR2424741A1 (xx)
GB (3) GB1598126A (xx)
IE (1) IE46676B1 (xx)
LU (1) LU79238A1 (xx)
NL (1) NL7802921A (xx)
PL (1) PL127781B1 (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205079A (en) * 1978-10-16 1980-05-27 Shell Oil Company Benzodioxincarboxamides
US4208424A (en) * 1979-04-26 1980-06-17 Shell Oil Company Lipogenesis inhibition by certain esters of substituted benzodioxincarboxylic acids
EP0019955A1 (en) * 1979-05-16 1980-12-10 Shell Internationale Researchmaatschappij B.V. Benzofurancarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions
FR2763335B1 (fr) * 1997-05-16 2000-11-24 Adir Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
DD137714A5 (de) 1979-09-19
GB1598126A (en) 1981-09-16
BE864918A (fr) 1978-09-15
IE46676B1 (en) 1983-08-24
GB1598128A (en) 1981-09-16
DE2811236A1 (de) 1978-09-28
NL7802921A (nl) 1978-09-19
IE780532L (en) 1978-09-17
FR2424741A1 (fr) 1979-11-30
DK117478A (da) 1978-09-18
LU79238A1 (fr) 1978-10-17
JPS53116377A (en) 1978-10-11
PL205322A1 (pl) 1979-06-04
PL127781B1 (en) 1983-11-30

Similar Documents

Publication Publication Date Title
Royer et al. Biologically active derivatives of gossypol: synthesis and antimalarial activities of peri-acylated gossylic nitriles
FI68398B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tetrazolylalkoxikarbostyrilderivat
EP0022317B1 (en) 2-oxo-benzothiazoline, benzoxazoline or indoline derivatives, their preparation, and pharmaceutical compositions comprising such derivatives
US4889871A (en) Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives
KR960000852B1 (ko) 퀴놀린형 메발로노락톤
SU1597100A3 (ru) Способ получени производных бензимидазола
KR100191774B1 (ko) 피라졸로[1,5-알파] 피리미딘 유도체 및 이것을 함유하는 항염증제
WO1992000011A2 (en) Leukotriene b4 antagonists
SE455422B (sv) Kinolonforeningar, forfarande for framstellning derav samt terapeutiska kompositioner innehallande dem
US4988682A (en) Myo-inositol analogs and method for their use
GB1598127A (en) Benzoxazine carboxamides having lipogenesis-inhibiting properties
EP0145010A2 (en) Carbostyril derivatives
EP0115142B1 (en) Chroman compounds
CA1168233A (en) Thioalkanoyl amino acids
US4785018A (en) Glycine derivatives
Salman et al. Studies in antifertility agents. 50. Stereoselective binding of d-and l-centchromans to estrogen receptors and their antifertility activity
Holmes et al. The chemistry of heterocyclic quinones. I. the direct oxidation of 6-hydroxycarbostyrils to carbostyril-5, 6-quinones
US4252818A (en) Novel benzopyran derivatives
US4521607A (en) Chromanyl glycines
EP0004270B1 (en) Streptovaricin c derivatives, a process for their preparation and antiviral compositions containing them
US4937390A (en) Compound useful for the production of 3-deoxy-3-fluoro-myo-inositol
GB2106516A (en) Anthranilic acid esters
US4180572A (en) Lipogenesis control by esters of benzoxazinecarboxylic acids
JPS61143334A (ja) ５，８−ジヒドロキシ−１，４−ナフトキノン誘導体
CA1140856A (en) Lipogenesis inhibiting composition and process for its preparation

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee