FR2424741A1 - Compositions biologiquement actives contre la formation de lipides et de cholesterol chez les mammiferes - Google Patents

Compositions biologiquement actives contre la formation de lipides et de cholesterol chez les mammiferes

Info

Publication number
FR2424741A1
FR2424741A1 FR7807462A FR7807462A FR2424741A1 FR 2424741 A1 FR2424741 A1 FR 2424741A1 FR 7807462 A FR7807462 A FR 7807462A FR 7807462 A FR7807462 A FR 7807462A FR 2424741 A1 FR2424741 A1 FR 2424741A1
Authority
FR
France
Prior art keywords
cholesterol
mammals
formation
biologically active
fat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7807462A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shell Internationale Research Maatschappij BV
Original Assignee
Shell Internationale Research Maatschappij BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/778,535 external-priority patent/US4118507A/en
Priority claimed from US05/779,648 external-priority patent/US4103021A/en
Application filed by Shell Internationale Research Maatschappij BV filed Critical Shell Internationale Research Maatschappij BV
Publication of FR2424741A1 publication Critical patent/FR2424741A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPOSITIONS BIOLOGIQUEMENT ACTIVES CONTRE LA FORMATION DE LIPIDES ET DE CHOLESTEROL CHEZ LES MAMMIFERES. LE CONSTITUANT ACTIF EST UN COMPOSE BICYCLIQUE AROMATISE SUBSTITUE DANS LEQUEL UN DES NOYAUX EST UNE STRUCTURE A NOYAU HETEROCYCLIQUE CONTENANT DE L'OXYGENE. PLUS PARTICULIEREMENT, LE CONSTITUANT ACTIF EST UN COMPOSE DE LA FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE X EST
FR7807462A 1977-03-17 1978-03-15 Compositions biologiquement actives contre la formation de lipides et de cholesterol chez les mammiferes Withdrawn FR2424741A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77881677A 1977-03-17 1977-03-17
US77853477A 1977-03-17 1977-03-17
US05/778,535 US4118507A (en) 1977-03-17 1977-03-17 Benzodioxincarboxamide lipogenesis inhibitors
US05/779,648 US4103021A (en) 1977-03-21 1977-03-21 Method of lowering blood lipid levels in mammals
US79175877A 1977-04-28 1977-04-28

Publications (1)

Publication Number Publication Date
FR2424741A1 true FR2424741A1 (fr) 1979-11-30

Family

ID=27542199

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7807462A Withdrawn FR2424741A1 (fr) 1977-03-17 1978-03-15 Compositions biologiquement actives contre la formation de lipides et de cholesterol chez les mammiferes

Country Status (11)

Country Link
JP (1) JPS53116377A (fr)
BE (1) BE864918A (fr)
DD (1) DD137714A5 (fr)
DE (1) DE2811236A1 (fr)
DK (1) DK117478A (fr)
FR (1) FR2424741A1 (fr)
GB (3) GB1598127A (fr)
IE (1) IE46676B1 (fr)
LU (1) LU79238A1 (fr)
NL (1) NL7802921A (fr)
PL (1) PL127781B1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763335A1 (fr) * 1997-05-16 1998-11-20 Adir Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202818A (en) * 1978-10-16 1980-05-13 Shell Oil Company Lipogenesis inhibition by certain esters of substituted benzodioxincarboxylic acids
US4208424A (en) * 1979-04-26 1980-06-17 Shell Oil Company Lipogenesis inhibition by certain esters of substituted benzodioxincarboxylic acids
EP0019955A1 (fr) * 1979-05-16 1980-12-10 Shell Internationale Researchmaatschappij B.V. Dérivés d'acide benzofuranne-carboxylique, leur préparation et leur utilisation dans des compositions inhibant la lipogenèse

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF MEDICINAL CHEMISTRY, vol. 17, no. 1, 1974, pages 41-45, Washington, US; N.J. LEWIS et al.: "Differential effects of benzodioxane, chroman, and dihydrobenzofuran analogs of clofibrate on various parameters of hepatic drug metabolism" *
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 77, 1955, pages 5373-5374, Washington, US; J. KOO et. al.: "Derivatives of 1,4-benzodioxan. I. 1,4-Benzodioxan-2-carboxamides" *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763335A1 (fr) * 1997-05-16 1998-11-20 Adir Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO1998052935A1 (fr) * 1997-05-16 1998-11-26 Adir Et Compagnie Composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
NL7802921A (nl) 1978-09-19
GB1598126A (en) 1981-09-16
GB1598127A (en) 1981-09-16
DD137714A5 (de) 1979-09-19
GB1598128A (en) 1981-09-16
DK117478A (da) 1978-09-18
JPS53116377A (en) 1978-10-11
BE864918A (fr) 1978-09-15
LU79238A1 (fr) 1978-10-17
PL205322A1 (pl) 1979-06-04
PL127781B1 (en) 1983-11-30
IE46676B1 (en) 1983-08-24
DE2811236A1 (de) 1978-09-28
IE780532L (en) 1978-09-17

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Legal Events

Date Code Title Description
ST Notification of lapse