GB1597140A - Tetralines - Google Patents

Tetralines Download PDF

Info

Publication number
GB1597140A
GB1597140A GB50477/77A GB5047777A GB1597140A GB 1597140 A GB1597140 A GB 1597140A GB 50477/77 A GB50477/77 A GB 50477/77A GB 5047777 A GB5047777 A GB 5047777A GB 1597140 A GB1597140 A GB 1597140A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
compound
carbon atoms
group
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB50477/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1597140A publication Critical patent/GB1597140A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
GB50477/77A 1976-12-07 1977-12-05 Tetralines Expired GB1597140A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1535376 1976-12-07
CH8277 1977-01-05

Publications (1)

Publication Number Publication Date
GB1597140A true GB1597140A (en) 1981-09-03

Family

ID=25683446

Family Applications (1)

Application Number Title Priority Date Filing Date
GB50477/77A Expired GB1597140A (en) 1976-12-07 1977-12-05 Tetralines

Country Status (17)

Country Link
JP (1) JPS5384955A (US20020095090A1-20020718-M00002.png)
AT (1) AT366361B (US20020095090A1-20020718-M00002.png)
CA (1) CA1105475A (US20020095090A1-20020718-M00002.png)
DE (1) DE2752659A1 (US20020095090A1-20020718-M00002.png)
DK (1) DK527877A (US20020095090A1-20020718-M00002.png)
ES (1) ES464747A1 (US20020095090A1-20020718-M00002.png)
FI (1) FI773595A (US20020095090A1-20020718-M00002.png)
FR (1) FR2373513A1 (US20020095090A1-20020718-M00002.png)
GB (1) GB1597140A (US20020095090A1-20020718-M00002.png)
IE (1) IE45929B1 (US20020095090A1-20020718-M00002.png)
IL (1) IL53533A (US20020095090A1-20020718-M00002.png)
NL (1) NL7713364A (US20020095090A1-20020718-M00002.png)
NZ (1) NZ185884A (US20020095090A1-20020718-M00002.png)
PH (1) PH13932A (US20020095090A1-20020718-M00002.png)
PT (1) PT67365B (US20020095090A1-20020718-M00002.png)
SE (1) SE7713471L (US20020095090A1-20020718-M00002.png)
SU (1) SU927110A3 (US20020095090A1-20020718-M00002.png)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448990A (en) * 1982-11-16 1984-05-15 Eli Lilly And Company Hydroxyaminotetralincarboxamides
US4500545A (en) * 1982-11-16 1985-02-19 Eli Lilly And Company Hydroxyaminotetralincarboxamides
GB2157950A (en) * 1984-05-04 1985-11-06 Nelson Res & Dev Selective D-2 dopamine receptor agonist
US4564628A (en) * 1983-01-03 1986-01-14 Nelson Research & Development Co. Substituted 2-aminotetralins
US4657925A (en) * 1984-08-13 1987-04-14 Nelson Research & Development Co. Method and compositions for reducing the intraocular pressure of mammals
WO1987005602A1 (en) * 1986-03-17 1987-09-24 Nelson Research And Development Company Substituted 2-aminotetralins
US4743618A (en) * 1983-01-03 1988-05-10 Nelson Research & Development Co. Substituted 2-aminotetralins
EP0334538A1 (en) 1988-03-25 1989-09-27 The Upjohn Company Therapeutically useful tetralin derivatives
US5177112A (en) * 1983-01-03 1993-01-05 Whitby Research, Inc. Substituted 2-aminotetralins
US5180746A (en) * 1989-02-17 1993-01-19 Takeda Chemical Industries, Ltd. Aralkylamine compounds
US5214156A (en) * 1988-03-25 1993-05-25 The Upjohn Company Therapeutically useful tetralin derivatives
US5225596A (en) * 1989-01-09 1993-07-06 The Upjohn Company Halo substituted aminotetralins

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS639500B2 (US20020095090A1-20020718-M00002.png) * 1978-07-14 1988-02-29 Amerikan Hosupitaru Sapurai Corp
US4314082A (en) * 1978-07-14 1982-02-02 American Hospital Supply Corporation Derivatives of 2-amino-6,7-dihydroxytetrahydro naphthalene (ADTN)
DE3062971D1 (en) 1979-09-14 1983-06-09 Sandoz Ag Derivatives of tetraline, their preparation and medicaments containing these compounds
EP0033789B1 (en) * 1980-01-30 1984-03-07 American Hospital Supply Corporation 2-alpha-methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene, its salts, and a process for preparation thereof
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
AU8455082A (en) * 1981-05-11 1982-12-07 Folk Lars-Erik Arvidsson Therapeutically useful tetralin derivatives iii,processes forpreparation and pharmaceutical preparations for such compounds
US4559359A (en) * 1981-06-23 1985-12-17 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4578403A (en) * 1981-06-23 1986-03-25 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4455317A (en) * 1981-06-23 1984-06-19 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4402974A (en) 1981-06-23 1983-09-06 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4454154A (en) * 1981-06-23 1984-06-12 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
IT1218322B (it) * 1982-06-10 1990-04-12 Chiesi Farma Spa Derivati di 1,2,3,4-tetraidronaftalene,procedimento di preparazione e relative composizioni farmaceutiche
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
AU650106B2 (en) * 1991-03-07 1994-06-09 Zeria Pharmaceutical Co., Ltd. Trialkylamine derivative and ameliorant for digestive tract movement containing the same
PT923542E (pt) * 1996-05-31 2003-12-31 Upjohn Co Aminas ciclicas substituidas no arilo como ligandos selectivos de dopamina d3
IT1294931B1 (it) * 1997-09-22 1999-04-23 Sigma Tau Ind Farmaceuti Derivati della 2-amminotetralina procedimento per la loro preparazione e composizioni farmaceutiche che li contengono, attive nella
AR054363A1 (es) * 2005-05-23 2007-06-20 Astrazeneca Ab Compuestos que exhiben actividad moduladora en el receptor 5-hidroxi-triptamina 6
JP5643467B2 (ja) * 2011-06-27 2014-12-17 シャンドン リュイェ ファーマシューティカル カンパニー リミテッドＳｈａｎ Ｄｏｎｇ Ｌｕｙｅ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． 窒素置換のアミノ−５，６，７，８−テトラヒドロナフトールの工業的製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1017359A (en) * 1972-07-03 1977-09-13 Frederic P. Hauck Substituted cyclic polymethylene phenols

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500545A (en) * 1982-11-16 1985-02-19 Eli Lilly And Company Hydroxyaminotetralincarboxamides
US4448990A (en) * 1982-11-16 1984-05-15 Eli Lilly And Company Hydroxyaminotetralincarboxamides
US4743618A (en) * 1983-01-03 1988-05-10 Nelson Research & Development Co. Substituted 2-aminotetralins
US4564628A (en) * 1983-01-03 1986-01-14 Nelson Research & Development Co. Substituted 2-aminotetralins
US5177112A (en) * 1983-01-03 1993-01-05 Whitby Research, Inc. Substituted 2-aminotetralins
GB2157950A (en) * 1984-05-04 1985-11-06 Nelson Res & Dev Selective D-2 dopamine receptor agonist
US4657925A (en) * 1984-08-13 1987-04-14 Nelson Research & Development Co. Method and compositions for reducing the intraocular pressure of mammals
US4722933A (en) * 1985-12-20 1988-02-02 Nelson Research & Development Co. Substituted 2-aminotetralins
AU601961B2 (en) * 1985-12-20 1990-09-27 Whitby Research, Inc. Method for reducing the intraocular pressure of mammals
WO1987005602A1 (en) * 1986-03-17 1987-09-24 Nelson Research And Development Company Substituted 2-aminotetralins
EP0334538A1 (en) 1988-03-25 1989-09-27 The Upjohn Company Therapeutically useful tetralin derivatives
US5214156A (en) * 1988-03-25 1993-05-25 The Upjohn Company Therapeutically useful tetralin derivatives
US5225596A (en) * 1989-01-09 1993-07-06 The Upjohn Company Halo substituted aminotetralins
US5180746A (en) * 1989-02-17 1993-01-19 Takeda Chemical Industries, Ltd. Aralkylamine compounds

Also Published As

Publication number Publication date
PH13932A (en) 1980-11-04
JPS6214540B2 (US20020095090A1-20020718-M00002.png) 1987-04-02
DK527877A (da) 1978-06-08
AT366361B (de) 1982-04-13
PT67365B (fr) 1979-09-20
SU927110A3 (ru) 1982-05-07
NZ185884A (en) 1980-04-28
IE45929B1 (en) 1982-12-29
FR2373513B1 (US20020095090A1-20020718-M00002.png) 1980-08-22
IL53533A0 (en) 1978-03-10
DE2752659A1 (de) 1978-06-08
NL7713364A (nl) 1978-06-09
JPS5384955A (en) 1978-07-26
SE7713471L (sv) 1978-06-08
FI773595A (fi) 1978-06-08
CA1105475A (en) 1981-07-21
IL53533A (en) 1982-07-30
FR2373513A1 (fr) 1978-07-07
PT67365A (fr) 1978-01-01
IE45929L (en) 1978-06-07
ES464747A1 (es) 1979-01-01
ATA871977A (de) 1981-08-15

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Legal Events

Date Code Title Description
429A Application made for amendment of specification (sect. 29/1949)
429H Application (made) for amendment of specification now open to opposition (sect. 29/1949)
429D Case decided by the comptroller ** specification amended (sect. 29/1949)
PS Patent sealed [section 19, patents act 1949]
SP Amendment (slips) printed
PCNP Patent ceased through non-payment of renewal fee
PCPE Delete 'patent ceased' from journal

Free format text: 4924,PAGE 2290

PCNP Patent ceased through non-payment of renewal fee