GB1595233A - Production of an antibiotic - Google Patents
Production of an antibiotic Download PDFInfo
- Publication number
- GB1595233A GB1595233A GB47324/77A GB4732477A GB1595233A GB 1595233 A GB1595233 A GB 1595233A GB 47324/77 A GB47324/77 A GB 47324/77A GB 4732477 A GB4732477 A GB 4732477A GB 1595233 A GB1595233 A GB 1595233A
- Authority
- GB
- United Kingdom
- Prior art keywords
- fractions
- antibiotic
- deionized water
- combined
- column
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 16
- 235000015097 nutrients Nutrition 0.000 claims abstract description 16
- 241000958211 Streptomyces flavogriseus Species 0.000 claims abstract description 11
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- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
- C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74295876A | 1976-11-17 | 1976-11-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1595233A true GB1595233A (en) | 1981-08-12 |
Family
ID=24986929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB47324/77A Expired GB1595233A (en) | 1976-11-17 | 1977-11-14 | Production of an antibiotic |
Country Status (10)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ190994A (en) | 1978-07-24 | 1981-10-19 | Merck & Co Inc | Z-2-acylamino-3-monosubstituted propenoates |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1483142A (en) * | 1975-03-15 | 1977-08-17 | Beecham Group Ltd | Streptomycetal antibiotic |
| CH633554A5 (en) * | 1975-11-21 | 1982-12-15 | Merck & Co Inc | Process for the preparation of novel thienamycin derivatives. |
-
1977
- 1977-11-02 DK DK487977A patent/DK487977A/da unknown
- 1977-11-02 NL NL7712092A patent/NL7712092A/xx not_active Application Discontinuation
- 1977-11-03 SE SE7712430A patent/SE433621B/xx not_active IP Right Cessation
- 1977-11-08 ES ES463973A patent/ES463973A1/es not_active Expired
- 1977-11-11 PT PT67268A patent/PT67268B/pt unknown
- 1977-11-14 GB GB47324/77A patent/GB1595233A/en not_active Expired
- 1977-11-16 CH CH1401477A patent/CH634104A5/de not_active IP Right Cessation
- 1977-11-16 FR FR7734457A patent/FR2371448A1/fr active Granted
- 1977-11-16 DE DE19772751303 patent/DE2751303A1/de not_active Ceased
- 1977-11-17 JP JP13735677A patent/JPS5363397A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6310998B2 (enrdf_load_stackoverflow) | 1988-03-10 |
| DE2751303A1 (de) | 1978-05-18 |
| PT67268A (en) | 1977-12-01 |
| NL7712092A (nl) | 1978-05-19 |
| SE433621B (sv) | 1984-06-04 |
| SE7712430L (sv) | 1978-05-18 |
| PT67268B (en) | 1979-10-08 |
| DK487977A (da) | 1978-05-18 |
| ES463973A1 (es) | 1978-11-16 |
| JPS5363397A (en) | 1978-06-06 |
| FR2371448A1 (fr) | 1978-06-16 |
| CH634104A5 (en) | 1983-01-14 |
| FR2371448B1 (enrdf_load_stackoverflow) | 1980-03-14 |
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| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee | ||
| PCNP | Patent ceased through non-payment of renewal fee |