FR2371448A1 - Nouveaux b-lactames antibiotiques - Google Patents

Nouveaux b-lactames antibiotiques

Info

Publication number
FR2371448A1
FR2371448A1 FR7734457A FR7734457A FR2371448A1 FR 2371448 A1 FR2371448 A1 FR 2371448A1 FR 7734457 A FR7734457 A FR 7734457A FR 7734457 A FR7734457 A FR 7734457A FR 2371448 A1 FR2371448 A1 FR 2371448A1
Authority
FR
France
Prior art keywords
lactams
new antibiotic
antibiotic
new
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7734457A
Other languages
English (en)
Other versions
FR2371448B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2371448A1 publication Critical patent/FR2371448A1/fr
Application granted granted Critical
Publication of FR2371448B1 publication Critical patent/FR2371448B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention concerne un nouvel antibiotique. Il s'agit d'un composé ayant la structure suivante :
FR7734457A 1976-11-17 1977-11-16 Nouveaux b-lactames antibiotiques Granted FR2371448A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74295876A 1976-11-17 1976-11-17

Publications (2)

Publication Number Publication Date
FR2371448A1 true FR2371448A1 (fr) 1978-06-16
FR2371448B1 FR2371448B1 (fr) 1980-03-14

Family

ID=24986929

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7734457A Granted FR2371448A1 (fr) 1976-11-17 1977-11-16 Nouveaux b-lactames antibiotiques

Country Status (10)

Country Link
JP (1) JPS5363397A (fr)
CH (1) CH634104A5 (fr)
DE (1) DE2751303A1 (fr)
DK (1) DK487977A (fr)
ES (1) ES463973A1 (fr)
FR (1) FR2371448A1 (fr)
GB (1) GB1595233A (fr)
NL (1) NL7712092A (fr)
PT (1) PT67268B (fr)
SE (1) SE433621B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0010573A1 (fr) 1978-07-24 1980-05-14 Merck & Co. Inc. Acides Z-2-acylamino-propéniques monosubstitués en position 3 et leurs esters et sels et procédés pour leur préparation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2304351A1 (fr) * 1975-03-15 1976-10-15 Beecham Group Ltd Nouvel antibiotique
FR2332015A1 (fr) * 1975-11-21 1977-06-17 Merck & Co Inc Derives o-,n- et carboxyles de thienamycine utiles comme antibiotiques

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2304351A1 (fr) * 1975-03-15 1976-10-15 Beecham Group Ltd Nouvel antibiotique
FR2332015A1 (fr) * 1975-11-21 1977-06-17 Merck & Co Inc Derives o-,n- et carboxyles de thienamycine utiles comme antibiotiques

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0010573A1 (fr) 1978-07-24 1980-05-14 Merck & Co. Inc. Acides Z-2-acylamino-propéniques monosubstitués en position 3 et leurs esters et sels et procédés pour leur préparation

Also Published As

Publication number Publication date
GB1595233A (en) 1981-08-12
ES463973A1 (es) 1978-11-16
PT67268A (en) 1977-12-01
JPS5363397A (en) 1978-06-06
DE2751303A1 (de) 1978-05-18
JPS6310998B2 (fr) 1988-03-10
CH634104A5 (en) 1983-01-14
FR2371448B1 (fr) 1980-03-14
SE7712430L (sv) 1978-05-18
NL7712092A (nl) 1978-05-19
SE433621B (sv) 1984-06-04
DK487977A (da) 1978-05-18
PT67268B (en) 1979-10-08

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Legal Events

Date Code Title Description
ST Notification of lapse